Immunological And Respiratory Effects Among Workers Exposed To Engineered Nanoparticles
Funder
National Health and Medical Research Council
Funding Amount
$513,507.00
Summary
Laboratory studies suggest that nanoparticles can easily enter the body and may cause more damage than similar, larger particles but human data are lacking. We propose to study the health of nanoparticle-exposed workers and unexposed workers, and compare biomarkers of inflammation in the blood and the respiratory system at the start and end of the shift, end of the working week and after 1 year’s further exposure to nanoparticles.
A Phase Two Clinical Trial Of A Program Delivered By Aboriginal Health Workers To Prevent Early Childhood Caries In Aboriginal Children.
Funder
National Health and Medical Research Council
Funding Amount
$553,905.00
Summary
The severe impact of early childhood dental caries on Aboriginal children highlights the need for the development of evidence-based community oral health strategies which are appropriate to the needs and resources of Aboriginal families and their health care services. This study responds to this need through the evaluation of a family centred oral health strategy developed in consultation with Aboriginal Community Controlled Health Services which is delivered by Aboriginal Health Workers.
Vitamin D Supplementation To Prevent Respiratory Infections Among Indigenous Children In The Northern Territory: A Randomised Controlled Trial.
Funder
National Health and Medical Research Council
Funding Amount
$3,164,379.00
Summary
Acute respiratory infections remain unacceptably common among Indigenous children in the Northern Territory. Most Indigenous infants are born with suboptimal vitamin D levels and this is associated with an increased risk of ARI. We propose to conduct a clinical trial to determine whether daily vitamin D supplementation, during the third trimester of pregnancy and early infancy, can reduce the risk of infant ARI during the first 12 months of life.
A Novel Multi-gene Marker Blood Test To Increase Community Participation In Colorectal Cancer Screening.
Funder
National Health and Medical Research Council
Funding Amount
$581,116.00
Summary
Bowel cancer screening programs are vital for early detection and prevention, but participation with the traditional faecal testing mode is less than 35%. Reasons include dislike or unsuitability for faecal testing. These barriers could be overcome and participation could increase using a different sampling mode for the screening test. We have developed a blood test for bowel cancer and will investigate if people who will not screen with the stool test will screen with the blood test instead.
Fall Prevention And Physical Activity Promotion For Older Adults: Cluster Trial Of Effectiveness And Cost-effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$1,291,950.00
Summary
This cluster randomised controlled trial will establish the impact on physical activity and falls of an intervention program that targets both physical activity and falls using assessment, advice and health coaching. The trial will involve 60 established groups of older people, recruited from local chapters of community organisations including Probus, the Older Women’s Network, registered clubs and church groups (estimated average group size of 10; total n = 600).
My Baby's Movements: A Stepped Wedged Cluster Randomised Trial Of Maternal Awareness And Reporting Of Decreased Fetal Movements To Reduce Stillbirth
Funder
National Health and Medical Research Council
Funding Amount
$1,431,444.00
Summary
Stillbirth is devastating for parents and families. Many stillbirths occur late in pregnancy due to deteriorating health of the baby that can be detected by the mother through a decrease in the baby’s movements. 'My Baby's Movements’ is a personalised, user-controlled and interactive mobile phone tool provided as part of routine care to pregnant women to promote general awareness of their baby’s movements. This trial aims to reduce stillbirth rates by early reporting of decreased movements.
A Longitudinal Controlled Study To Prevent Early Childhood Caries From Ages 0-6 Years In A Disadvantaged Community In Queensland
Funder
National Health and Medical Research Council
Funding Amount
$695,788.00
Summary
Rampant dental decay in young children is very difficult to prevent. The study will follow a group of high risk children from birth to 6 years of age to test the effectiveness of antibacterial and remineralising agents to prevent dental decay. Our early results showed that these agents have good potential for removing decay-causing bacteria and preventing dental cavities. We expect our long term results will yield valuable information for dental prevention for young children worldwide.
Minimally Invasive Approach To Manage Early Childhood Caries In Aboriginal Preschoolers
Funder
National Health and Medical Research Council
Funding Amount
$1,488,220.00
Summary
The treatment of dental decay in young children is often undertaken in a hospital, which is costly and risky. A treatment approach tested among a non-Aboriginal preschool population in WA, using hand instruments only and without the use of local anaesthesia, showed nearly a ten-fold reduction in the need for specialist dental care. This study will test the effectiveness of dental treatment of preschool children in rural and remote Aboriginal communities, using the alternative approach.
Better Methods To Collect Self-report Data On Alcohol Use Behaviours From Aboriginal And Torres Strait Islander Australians
Funder
National Health and Medical Research Council
Funding Amount
$2,211,435.00
Summary
This project will develop, refine and trial a tablet computer tool for assessing drinking among Aboriginal and Torres Strait Islander Australians. This tool will ‘speak’ to the person (in local language if needed) and use an engaging touchscreen display; it will add up amount consumed if a person shares alcohol or drinks from non-standard containers. The tool will help provide accurate survey data for service planning and community feedback, and can be adapted for healthcare screening.
Preventing Chronic Disease In Patients With Low Health Literacy Using E-health And Teamwork In Primary Health Care.
Funder
National Health and Medical Research Council
Funding Amount
$1,264,893.00
Summary
This study will evaluate whether an innovative intervention tailored to patients’ health literacy improves preventive care for vulnerable and disadvantaged patients in general practice. It will use e-health to support practice nurses to reduce their patients’ risk of chronic disease.