Chemical Synthesis and Biological Evaluation of Analogues of Platencin, a New-generation Antibiotic. The just discovered natural product platencin displays potent and broad spectrum anti-bacterial activity. It may represent the precursor of a new class of drugs to replace current anti-infective agents which are becoming alarmingly less effective as bacterial resistance increases dramatically. For this reason, platencin has been described as a once in a generation discovery. This study will explo ....Chemical Synthesis and Biological Evaluation of Analogues of Platencin, a New-generation Antibiotic. The just discovered natural product platencin displays potent and broad spectrum anti-bacterial activity. It may represent the precursor of a new class of drugs to replace current anti-infective agents which are becoming alarmingly less effective as bacterial resistance increases dramatically. For this reason, platencin has been described as a once in a generation discovery. This study will exploit two sophisticated new synthetic techniques for the purposes of making analogues of platencin that will be screened by the industry partner, Biota, for anti-bacterial properties. New drug candidates capable of treating especially dangerous infections such as methicillin resistant staphyllococcus aureus (MRSA) should thus emerge.Read moreRead less
Aboriginal and non-Aboriginal sex-offenders in Australia: Assessing risk for practice and policy. A key priority of Australian governments is to improve community safety through reducing the risk of sex offenders re-offending after release from prison. This project will assess the validity of tools used to predict the risk of sexual offender recidivism and identify alternate risk assessment tools for Indigenous and non-Indigenous sex offenders.
Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent co ....Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent corruption and other integrity violations; coordinate the work of integrity institutions; ensure their accountability; and measure the effectiveness of integrity and anti-corruption policy settings. This research is expected to contribute to better evaluation of integrity policies worldwide.Read moreRead less
Missing girls: From childhood runaways to criminalised women. This study examines the link between girls declared ‘missing’ and their trajectory into the criminal justice system, expanding the Australian knowledge base along with providing a clear, tangible practice framework to prevent the drift into youth and adult criminal justice systems. By addressing concerns of practitioners and policy makers this significant research increases the visibility of a marginalised groups, exploring individual ....Missing girls: From childhood runaways to criminalised women. This study examines the link between girls declared ‘missing’ and their trajectory into the criminal justice system, expanding the Australian knowledge base along with providing a clear, tangible practice framework to prevent the drift into youth and adult criminal justice systems. By addressing concerns of practitioners and policy makers this significant research increases the visibility of a marginalised groups, exploring individual and systemic impacts of missing girls entering the criminal justice and welfare systems. Findings of this research will detail opportunities for early intervention for service providers in addition to rich empirical data to better inform policy makers and service developers targeting at risk young people. Read moreRead less
Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems ....Optimising illicit dark net marketplace interventions. Optimising illicit dark net marketplace interventions. This project aims to develop and test a series of interventions to disrupt identify theft activities, and design an operational risk framework that will aid law enforcement agencies and organisations to timely and appropriately intervene in cyber space. The buying and selling of identity credentials via dark net forums is a significant and growing problem. This research— based on systems analyses of dark net forums, and bringing together researchers, practitioners, theories and methods from human factors, sociotechnical systems, criminology, and cyber security—is expected to increase understanding of the dark net and improve ways of disrupting identity theft and trading.Read moreRead less
Building an integrated system for Australian bushfire prevention. Building an integrated system for Australian bushfire prevention. This project aims to develop a comprehensive approach to prevent arson. Bushfires are a serious issue in Australia, made worse by climate change; since most of these fires are started by people, it is important to prevent arson. Building on previous work, this project intends to improve community responses, and build a model to predict risk and improve data sharing. ....Building an integrated system for Australian bushfire prevention. Building an integrated system for Australian bushfire prevention. This project aims to develop a comprehensive approach to prevent arson. Bushfires are a serious issue in Australia, made worse by climate change; since most of these fires are started by people, it is important to prevent arson. Building on previous work, this project intends to improve community responses, and build a model to predict risk and improve data sharing. The intended outcome is an all-risks approach to arson prevention and community engagement. This research should reduce the incidence of arson in Australia, and also be useful overseas.Read moreRead less
Targeted crime: policing and social inclusion. This project will undertake a criminological study of the policing of targeted incidents and crime, that is, incidents and crimes motivated by bias, prejudice or hatred towards members of particular groups, communities and individuals. It will develop a best practice policing framework for targeted crimes and incidents.
Indigenous Justice Reports: new narratives and practices in sentencing. This project engages a participatory action research model to assess the impact of Indigenous Justice Reports in criminal sentencing on sentence practices and outcomes for Indigenous women. It introduces Indigenous Reports for Indigenous women in Victorian Koori Courts and expands their availability in Queensland Murri Courts. Its comparative research approach identifies how place-based factors influence the process and impa ....Indigenous Justice Reports: new narratives and practices in sentencing. This project engages a participatory action research model to assess the impact of Indigenous Justice Reports in criminal sentencing on sentence practices and outcomes for Indigenous women. It introduces Indigenous Reports for Indigenous women in Victorian Koori Courts and expands their availability in Queensland Murri Courts. Its comparative research approach identifies how place-based factors influence the process and impact of Indigenous Reports on sentencing. This project seeks to improve sentencing processes and outcomes for Indigenous defendants by providing courts with reports that address personal and community circumstances of Indigenous women, provide relevant sentencing options and are accompanied with appropriate supports.Read moreRead less
Improved Landfill Barrier Design for Changing Climates. The proposed research project will develop advanced methods and guidelines for practising engineers for improved engineering and design of waste containment barrier systems, leading to improved protection of groundwater resources and the environment and sustainable development of the country. The project will contribute to the priority area of building an environmentally sustainable Australia with a specific focus on water as a critical re ....Improved Landfill Barrier Design for Changing Climates. The proposed research project will develop advanced methods and guidelines for practising engineers for improved engineering and design of waste containment barrier systems, leading to improved protection of groundwater resources and the environment and sustainable development of the country. The project will contribute to the priority area of building an environmentally sustainable Australia with a specific focus on water as a critical resource.Read moreRead less
DIsrupting Child Exploitation - the DICE project. Child sexual exploitation is an insidious social problem which impacts the most vulnerable children and young people in Australia. The DICE project (Disrupting Child Sexual Exploitation) aims to develop a multi-agency response which pivots the focus of intervention to the sexual exploitation predators who target vulnerable young people in statutory care. Previous interventions have prioritised protecting (and controlling) the young people, with l ....DIsrupting Child Exploitation - the DICE project. Child sexual exploitation is an insidious social problem which impacts the most vulnerable children and young people in Australia. The DICE project (Disrupting Child Sexual Exploitation) aims to develop a multi-agency response which pivots the focus of intervention to the sexual exploitation predators who target vulnerable young people in statutory care. Previous interventions have prioritised protecting (and controlling) the young people, with limited success. Through a trauma informed approach which supports young people, combined with disruptive police strategies targeting perpetrators, and co-ordinated multiagency working, it is anticipated that there will be measurable changes to the protection of vulnerable young people. Read moreRead less