Separating The Adverse Neurodevelopmental Consequences Of Mechanical Ventilation And Postnatal Steroids In Preterm Lambs
Funder
National Health and Medical Research Council
Funding Amount
$1,752,863.00
Summary
Extremely premature infants often develop severe breathing difficulties and need the help of a machine to breathe. Certain steroids help to mature the lung and allow the baby to breathe on his own without help. However, both steroids and long periods on breathing machines may interfere with normal brain development. This study will help doctors to weigh up the long-term risks and benefits of giving a baby steroids to help them breathe on their own versus continuing mechanical ventilation without ....Extremely premature infants often develop severe breathing difficulties and need the help of a machine to breathe. Certain steroids help to mature the lung and allow the baby to breathe on his own without help. However, both steroids and long periods on breathing machines may interfere with normal brain development. This study will help doctors to weigh up the long-term risks and benefits of giving a baby steroids to help them breathe on their own versus continuing mechanical ventilation without steroids.Read moreRead less
Enhanced Control Of Hypertension And Thrombolysis Stroke Study (ENCHANTED)
Funder
National Health and Medical Research Council
Funding Amount
$4,408,568.00
Summary
This is an international multi-centre randomised controlled trial that is evaluating two approaches to improve the benefits, safety and costs associated with the treatment with the clot-busting drug in patients with acute stroke due to blocked blood vessel. The study aims to determine whether a slightly lower dose of the clot busting drug and more intensive control of elevated blood pressure will improve the chances of a patient recovering from this serious illness.