Human identification, ancient DNA and genomics. This project aims to develop and apply a novel targeted sequence capture and high throughput DNA sequencing approach to simultaneously type thousands of informative identity, ancestry and phenotype markers in a single assay to facilitate identification of unknown suspects and missing persons. DNA based human identification is both critical and central to criminal and coronial investigations, disaster-victim and missing persons identification, repat ....Human identification, ancient DNA and genomics. This project aims to develop and apply a novel targeted sequence capture and high throughput DNA sequencing approach to simultaneously type thousands of informative identity, ancestry and phenotype markers in a single assay to facilitate identification of unknown suspects and missing persons. DNA based human identification is both critical and central to criminal and coronial investigations, disaster-victim and missing persons identification, repatriation of war dead and counter-terrorism operations. Persistent technological and conceptual issues associated with the application of standard procedures to trace degraded DNA, or when profiles have no match in DNA databases, limit their application to real-world human identification problems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100154
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
The Advanced DNA Identification and Forensics Facility. The advanced DNA identification and forensics facility:
The project aims to establish a national integrated facility for cutting-edge forensic genetic research, resources and expertise in wildlife, forest and environmental DNA identification to improve our capacity to identify unknown biological material. The project’s goal will be to enhance synergies between academic research, service delivery and forensic application of DNA identificati ....The Advanced DNA Identification and Forensics Facility. The advanced DNA identification and forensics facility:
The project aims to establish a national integrated facility for cutting-edge forensic genetic research, resources and expertise in wildlife, forest and environmental DNA identification to improve our capacity to identify unknown biological material. The project’s goal will be to enhance synergies between academic research, service delivery and forensic application of DNA identification technologies, addressing vital questions such as: From which individual or species did this material originate? Where in the world is it from? Is it legal? The proposed facility may deliver applied outcomes for government, the criminal justice system, and industry, such as improved pest and threatened species identification; biosecurity, prosecutions of wildlife crime and illegal logging; and missing person and disaster victim identification.Read moreRead less
Meta-modelling of ecological, evolutionary and climatic systems dynamics. This project aims to improve forecasts of the response of biodiversity to future climate change and so improve on-ground conservation management. Using dynamic systems modelling, tested against field data from a wide variety of case studies, the project models will integrate a variety of biological and geophysical inputs to produce more realistic forecasts of change.
Systems modelling for synergistic ecological-climate dynamics. The project aims to improve forecasts of the response of biodiversity to future climate change and so improve on-ground conservation management. A systems modelling framework will be developed and tested against real-world data to integrate a wide variety of biological and geophysical inputs and so produce more realistic predictions.
Integrating models with molecular 'logbooks' to better forecast extinction risk from climate change. Current forecasts indicate that human-driven climate change will likely cause widespread biodiversity loss. However, climatic shifts during the Quaternary (2.6 million years ago to present), similar in magnitude to those projected for the 21st century, did not apparently cause extensive extinctions (with the exception of the megafauna). This project aims to use models linked to past responses imp ....Integrating models with molecular 'logbooks' to better forecast extinction risk from climate change. Current forecasts indicate that human-driven climate change will likely cause widespread biodiversity loss. However, climatic shifts during the Quaternary (2.6 million years ago to present), similar in magnitude to those projected for the 21st century, did not apparently cause extensive extinctions (with the exception of the megafauna). This project aims to use models linked to past responses imprinted in species’ genes to resolve whether the disparity between observed and predicted extinction rates comes from models over-predicting species loss due to climate change. It will use this genetic-demographic approach to improve predictions of biodiversity responses to global change by establishing the biological and environmental determinants of extinction.Read moreRead less
Reconstructing mechanisms of range contraction to avert species extinctions. This project aims to integrate biotic information from fossils and ancient DNA of vertebrates into computational models to establish ecological processes that drive the structure and dynamics of geographical ranges and regulate the severity of species extinction rates from global change. This approach is likely to improve theory on dynamic species borders and expected outcomes include providing a framework for better al ....Reconstructing mechanisms of range contraction to avert species extinctions. This project aims to integrate biotic information from fossils and ancient DNA of vertebrates into computational models to establish ecological processes that drive the structure and dynamics of geographical ranges and regulate the severity of species extinction rates from global change. This approach is likely to improve theory on dynamic species borders and expected outcomes include providing a framework for better allocating resources for endangered species in Australia and beyond. This will have significant benefits, such as providing the first mechanistic explanations for the principal drivers of mega-fauna extinctions during the late Pleistocene and Holocene.Read moreRead less