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Exploring Resistance Of Plasmodium Vivax To Antimalarial Drugs: A Retrospective And Prospective Study
Funder
National Health and Medical Research Council
Funding Amount
$439,230.00
Summary
Although previously considered a 'benign' form of the disease, vivax malaria is increasingly recognised as a cause of complications and even death. Unfortunately, the parasite is developing resistance to conventional drugs. Papua New Guinea was where resistance to chloroquine was first detected and other drugs are following suit. We plan to examine the parasite genes involved in this process, including before and after the introduction of a new strategy in PNG, artemisinin combination therapy.
Mapping Plasmodium Falciparum Population Structure And The Source Of Outbreaks In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$534,786.00
Summary
Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effec ....Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effective.Read moreRead less