Regulation Of Osteoclast Differentiation And Function By The PKC Pathway.
Funder
National Health and Medical Research Council
Funding Amount
$424,189.00
Summary
Developing strategies to control the formation of osteoclasts which underlines many disorders such as osteoporosis and osteoarthritis has been a major focus of bone research.The proposed research examines the fundamental role of Protein Kinase C (PKC) in bone resorption.This work will help elucidate the role of PKC in osteoclast formation;define the physiological role of PKC in bone structure and bone resorption in vivo and develop the treatment of bone disorders.