Potassium Channel Regulation Of Bacterial-driven Gastrointestinal Disease
Funder
National Health and Medical Research Council
Funding Amount
$576,000.00
Summary
Helicobacter pylori infections cause a chronic inflammation which in some people results in stomach cancer or ulcers. We have used a mouse with natural resistance to H. pylori gastritis to identify a completely novel regulator of the pathology induced by this infection. In this project, we will examine the mechanism by which this regulator protects against disease in mice, and examine its significance in the susceptibility of people to gastric cancer.