Reduction Of Chronic Post-surgical Pain With Ketamine - ROCKet Study
Funder
National Health and Medical Research Council
Funding Amount
$4,823,395.00
Summary
Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.
Physical, Lifestyle And Psychosocial Determinants Of Spinal Pain Development In Adolescents
Funder
National Health and Medical Research Council
Funding Amount
$682,800.00
Summary
This project aims to understand the development of back and neck pain in adolescence. By the age of 16 around half of all adolescents have suffered back pain and one third have suffered neck pain. For many adolescents this pain is disabling and over a third of sufferers miss school, miss recreation and seek medical help. The current understanding of back and neck pain in adolescence is quite limited - restricting the effectiveness of initiatives to prevent adolescents having to suffer spinal pai ....This project aims to understand the development of back and neck pain in adolescence. By the age of 16 around half of all adolescents have suffered back pain and one third have suffered neck pain. For many adolescents this pain is disabling and over a third of sufferers miss school, miss recreation and seek medical help. The current understanding of back and neck pain in adolescence is quite limited - restricting the effectiveness of initiatives to prevent adolescents having to suffer spinal pain and of treatment of those adolescents unlucky enough to have an episode. Better understanding and interventions for adolescent spinal pain will also have longer term implications by reducing adult spinal pain. Four out of 5 adults will experience spinal pain. In the USA treating adult back pain is the 4th largest health care cost. Many adults with chronic back pain had their first episode during adolescence. A better understanding of spinal pain in adolescence may help prevent it developing into a lifelong disability. We will collect information from 2,000 adolescents on their experience of back and neck pain and on potential physical, lifestyle and psychosocial risk factors. We believe factors such as their posture, muscle capacity, TV and computer use, mental health and social situation all combine to influence whether a person develops back or neck pain. The project is unique as it will not only collect a broad range of information during adolescence, but will also make use of a large database of health, developmental and psychosocial information already collected from these children since birth. With a better understanding of the development of spinal pain we will be able to develop guidelines to help prevent these problems. We will also be able to develop better treatment plans for sub-groups of adolescents with a particular combination of risk factors. Together these initiatives will assist in understanding and breaking the pathway to chronic spinal pain.Read moreRead less
Optimising biodegradation and removal of organic and inorganic pollutants in wastewater using constructed wetlands. The urgency of water recycling is dictated by drying climate and rapid expansion of population in Australia. Constructed wetlands are environmentally-benign way to purify wastewater by removing inorganics and facilitating biodegradation of organic pollutants, thus producing recycled water that can be used in a variety of fit-for-purpose applications. This project will produce a dec ....Optimising biodegradation and removal of organic and inorganic pollutants in wastewater using constructed wetlands. The urgency of water recycling is dictated by drying climate and rapid expansion of population in Australia. Constructed wetlands are environmentally-benign way to purify wastewater by removing inorganics and facilitating biodegradation of organic pollutants, thus producing recycled water that can be used in a variety of fit-for-purpose applications. This project will produce a decision-support system for optimising wetland performance in removing inorganics and biodegrading organic pollutants from wastewater, thus enhancing water recycling and reuse in this drying continent of ours.Read moreRead less
The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuil ....The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuilding.Read moreRead less
Rates, Patterns And Determinants Of Alcohol’s Harm To Others: A Cross-national Comparative Study
Funder
National Health and Medical Research Council
Funding Amount
$305,856.00
Summary
Alcohol causes harms to drinkers, and others around them, including spouses, children, family, friends, workmates and strangers. Australian and New Zealand work on alcohol’s harm to others is being replicated by the WHO in 7 countries (Chile, Nigeria, Sri Lanka, India, Thailand, Laos and Vietnam). We aim to analyse datasets from nine countries and compare the magnitude and patterning of problems across and within cultures – identifying opportunities for reducing harm from others’ drinking.
Technology is changing the lives of Australians. We need to understand the impact on health to gain the benefits with minimal harm. This fellowship will support a program of internationally leading research drawing together ergonomics, physiotherapy and physical activity expertise. Example projects include the impact of electronic games on children’s activity, walking workstations to increase physical activity of office workers and a family-based program for overweight adolescents.
Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.
A National Population-based Study Of Rheumatic Heart Disease In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$877,826.00
Summary
Whilst overall a rare disease, Indigenous peoples have disproportionately high rates of rheumatic heart disease (RHD). This study explores the prevalence and distribution of RHD in pregnancy in Australia and New Zealand. It details current management, diagnostic and referral process and risk factors. Key attributes of culturally safe models of care for RHD in pregnancy are explored, particularly as they relate to Indigenous women. Findings will inform policy, guidelines and education resources.
Arsenic and copper cycling in the soil-plant continuum in water-limited mining environments. This project will characterise cycling of arsenic and copper in the landscape after gold mining and will establish environmental risk-assessment framework. The results of this project will improve rehabilitation of mining-affected areas.