A Sequential Multiple Assignment Randomised Trial (SMART) Of Nursing Interventions To Reduce Pain Associated With Chemotherapy Induced Peripheral Neuropathy
Funder
National Health and Medical Research Council
Funding Amount
$713,418.00
Summary
Modern chemotherapy treatments can result in damage to the peripheral nerves, resulting in a condition called peripheral neuropathy. This condition is characterised by a range of sensory and functional changes that can cause pain and reduced ability to perform daily activities. This project will test various non-pharmacological pain management measures to determine if they are effective in improving the quality of life of patients who experience this problem.
GABA(B) Receptor Modulation Of Gastrointestinal Function In Health And Disease By Alpha-Conotoxins
Funder
National Health and Medical Research Council
Funding Amount
$689,050.00
Summary
Chronic visceral pain is a common and debilitating condition arising from numerous diseases that affect our internal organs. There is a desperate need for more information about the mechanisms responsible for signalling chronic visceral pain to provide therapies and potentially find a cure for it. Our research focuses on ?-conotoxins (small peptides from marine cone snail venom) as novel potential therapeutic agents for the treatment of chronic visceral pain.
The role of the immune system in pain is emerging from recent discoveries, and may hold the key to novel pain treatments. Most people experience brief gut infections from food or contagion without long-term consequences. Many others suffer symptoms for years afterwards - probably the best example of immune-based pain. Our project investigates how immune cells communicate with sensory nerves, and how these communications change from both angles after gut infection or inflammation.
Transient Receptor Potential Channels (TRPs) As Transducers And Targets In Primary Visceral Afferents
Funder
National Health and Medical Research Council
Funding Amount
$669,130.00
Summary
Transient receptor potential, or TRP channels, are involved in generating many of the sensations we perceive, such as heat, cold, touch and pain. Some TRP channels are specialized to signal pain from visceral organs, which we must investigate if we are to find treatments for visceral pain, which are currently lacking.
Special Research Initiatives - Grant ID: SR0354804
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impac ....ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impacts of contaminated soil and wastes, and land remediation. By facilitating communication, the network enhances national and international research coordination, interaction with regulators, end-users, industry, and other stakeholders, achievement of critical mass for new initiatives, enhances research training and contributes to a critical National Priority.Read moreRead less
Local government, mining companies and resources development in regional Australia: meeting the governance challenge. Sustainable regional development and continuing growth of the resources sector are key national priorities. The current resources boom is placing significant pressure on the physical, social and governance infrastructure of mining-intensive regions. Unless these issues can be better managed, new resource projects risk being delayed or deferred and the trend to fly-in fly-out oper ....Local government, mining companies and resources development in regional Australia: meeting the governance challenge. Sustainable regional development and continuing growth of the resources sector are key national priorities. The current resources boom is placing significant pressure on the physical, social and governance infrastructure of mining-intensive regions. Unless these issues can be better managed, new resource projects risk being delayed or deferred and the trend to fly-in fly-out operations will be accelerated, with deleterious consequences for sustainable regional growth. This project will contribute to a more effective response to these challenges by investigating the changing nature of local level governance in mining intensive regions and how these arrangements can be improved.Read moreRead less
A screening human health risk assessment for developing coal seam gas water resources in Queensland, Australia. Due to its rich coal seam deposits, Queensland is projected to become Australia's leading coal seam gas (CSG) producer, contributing significantly to the State's economy and national "clean" energy targets. Over a 30 year period, it is estimated that Queensland's CSG industry could also create by-product water of sufficient volume to beneficially augment the State's future water supply ....A screening human health risk assessment for developing coal seam gas water resources in Queensland, Australia. Due to its rich coal seam deposits, Queensland is projected to become Australia's leading coal seam gas (CSG) producer, contributing significantly to the State's economy and national "clean" energy targets. Over a 30 year period, it is estimated that Queensland's CSG industry could also create by-product water of sufficient volume to beneficially augment the State's future water supply demands. The proposed screening Health Risk Assessment will evaluate the relative risks associated with human exposure to raw and treated CSG by-product water contaminants, informing public debate on this matter, and guide policy development within the complex multi-sector regulatory framework in place for CSG water resource development in Queensland.Read moreRead less
Cycle Aware: Driving with Bikes. This project focuses on the education and training required by drivers to interact safely with cyclists. It uses two ontologically diverse methodologies to examine how Australian drivers become cyclist aware and the education and training necessary to foster safe driver–cyclist interactions. The project aims to provide a critical knowledge base for state and territory driver education policies and a cycle-aware module for learner drivers. These outcomes are inten ....Cycle Aware: Driving with Bikes. This project focuses on the education and training required by drivers to interact safely with cyclists. It uses two ontologically diverse methodologies to examine how Australian drivers become cyclist aware and the education and training necessary to foster safe driver–cyclist interactions. The project aims to provide a critical knowledge base for state and territory driver education policies and a cycle-aware module for learner drivers. These outcomes are intended to reduce cyclist road trauma and on-road tensions between cyclists and drivers, and to improve opportunities for active travel to tackle the growing issue of inactivity.Read moreRead less
Water Scarcity and rural social hardship - can water markets alleviate the problem? Present review of water resources within catchments of the Murray-Darling Basin will result in reduced access to water for consumptive use with consequential significant socio-economic and community impacts. Water markets are seen as major instruments to assist farmers in managing this process and thereby minimize the impact within rural communities. However, research has identified several barriers to trade an ....Water Scarcity and rural social hardship - can water markets alleviate the problem? Present review of water resources within catchments of the Murray-Darling Basin will result in reduced access to water for consumptive use with consequential significant socio-economic and community impacts. Water markets are seen as major instruments to assist farmers in managing this process and thereby minimize the impact within rural communities. However, research has identified several barriers to trade and several future research needs. This project addresses five of these issues by providing insight into three community barriers to trade as well as a framework for ongoing monitoring, analyses and reporting of market outcomes and impacts to assist adaptive policy development.Read moreRead less
Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australi ....Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australians. The project is significant because it adopts a sector-wide view to systematically define social risk, co-create a social risk management framework and implement it via a new social risk management toolkit. This should lessen harm to communities, reduce delays and costs and benefit national infrastructure delivery.Read moreRead less