Improving Pain And Movement Outcomes In Symptomatic Knee Osteoarthritis
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
People fear getting painful knee osteoarthritis (OA) more than any other disease – it is seen as progressive and incurable. It often stops people from moving and staying healthy, resulting in an enormous burden on sufferers and the health care system. This program of research aims to understand what brain & nervous system processes might underlie these pain and movement problems and whether new brain-targeting treatment helps. This will allow us to better match treatment to what patients need.
The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuil ....The Australian historic shipwreck protection project: the in situ preservation and reburial of a colonial trader - Clarence (1850). The project will use cutting-edge technology to study and preserve an early colonial shipwreck at risk and develop a world-class strategy for the reburial and preservation of endangered historic shipwrecks. The project will help develop new national policy and technical guidelines for site managers of historic shipwrecks and offer new insights into colonial shipbuilding.Read moreRead less
GABA(B) Receptor Modulation Of Gastrointestinal Function In Health And Disease By Alpha-Conotoxins
Funder
National Health and Medical Research Council
Funding Amount
$689,050.00
Summary
Chronic visceral pain is a common and debilitating condition arising from numerous diseases that affect our internal organs. There is a desperate need for more information about the mechanisms responsible for signalling chronic visceral pain to provide therapies and potentially find a cure for it. Our research focuses on ?-conotoxins (small peptides from marine cone snail venom) as novel potential therapeutic agents for the treatment of chronic visceral pain.
Impact of industrially based endocrine disrupting chemicals on aquatic biota. Endocrine disrupting chemicals (EDCs) are a serious threat to aquatic organisms, livestock and humans. EDCs are present in water discharged from sewage treatment plants and in leachate from contaminated land. This project will determine the impact of EDCs from contaminated landfill on aquatic animals. It will also identify the chemicals responsible for biological impact by developing new bio-assays suitable for industr ....Impact of industrially based endocrine disrupting chemicals on aquatic biota. Endocrine disrupting chemicals (EDCs) are a serious threat to aquatic organisms, livestock and humans. EDCs are present in water discharged from sewage treatment plants and in leachate from contaminated land. This project will determine the impact of EDCs from contaminated landfill on aquatic animals. It will also identify the chemicals responsible for biological impact by developing new bio-assays suitable for industrial, scientific and regulatory authority applications. This research has wide-ranging relevance and value to Australian State and Federal regulators and industries because of the ubiquity of sewage treatment plants and contaminated leachate from landfills.Read moreRead less
Quantitative metrics for determining aquifer ecosystem state. Clean groundwater comes from dirty surface water by way of biological purification. This project will develop quantitative ways to assess groundwater ecosystems to ensure the sustainable extraction of water and maintenance of these crucial ecosystems.
Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australi ....Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australians. The project is significant because it adopts a sector-wide view to systematically define social risk, co-create a social risk management framework and implement it via a new social risk management toolkit. This should lessen harm to communities, reduce delays and costs and benefit national infrastructure delivery.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100141
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality c ....High-resolution ITRAX XRF core scanning facility for global change research. This facility will enable researchers to obtain high-resolution geochemical profiles in the study of environmental change and climate variability. It will provide archive data on the variation of density and chemical element composition along sediment and soil cores, rock cores, wood samples, speleothems and corals. These archives contain important information such as human activity, climate variability, water quality changes, pollution histories, recent geomorphological change, land-use change, introduction of invasive species and the occurrence of bushfires. A better understanding of the occurrence and timing of these major environmental issues is of national and regional importance.Read moreRead less