Genes to phenotype: Exploiting the marsupial model. This research will exploit one of Australia's finest natural resources, its marsupial fauna. The features of marsupial reproduction and development provide a unique opportunity to answer fundamental biological questions. This research will show how the minor differences in key developmental genes that have arisen in their 100 million year isolation give rise to the characteristic differences in developmental timing and reproduction between mar ....Genes to phenotype: Exploiting the marsupial model. This research will exploit one of Australia's finest natural resources, its marsupial fauna. The features of marsupial reproduction and development provide a unique opportunity to answer fundamental biological questions. This research will show how the minor differences in key developmental genes that have arisen in their 100 million year isolation give rise to the characteristic differences in developmental timing and reproduction between marsupials and other mammals. The focus on reproduction and development will also provide invaluable knowledge to underpin efforts to conserve our endangered species and to control those that are overabundant.Read moreRead less
Domestic air quality: towards the setting of guidelines. Air quality standards have been developed to protect human health. Although people spend most of their time indoors there are no standards and only a few guidelines for indoor air pollution (IAP). The aim of this study is to investigate the levels of IAP that may worsen asthma in children. Childhood asthma will be used as a health indicator due to its high prevalence, cost to the healthcare system and implications for respiratory morbidity ....Domestic air quality: towards the setting of guidelines. Air quality standards have been developed to protect human health. Although people spend most of their time indoors there are no standards and only a few guidelines for indoor air pollution (IAP). The aim of this study is to investigate the levels of IAP that may worsen asthma in children. Childhood asthma will be used as a health indicator due to its high prevalence, cost to the healthcare system and implications for respiratory morbidity in adult life. We expect to identify levels of IAP that will represent a health risk as well as the factors that may contribute to increased IAP in homes.Read moreRead less
Gravitational-wave astrophysics of binary black holes. Do black holes live alone, or form lasting gravitational partnerships? This question is of immense significance to astronomers. The emerging field of gravitational-wave astronomy is set to provide the answers. This project aims to develop innovative strategies to search for black hole pairs using leading technologies built with Australian expertise.
Testing pulsar emission models and general relativity at pico arcsecond resolution. A holographic technique has been pioneered that harnesses scattering in interstellar space to resolve the emission from pulsars at a resolution of 50 pico-arcseconds, six orders of magnitude finer than has been achieved by conventional radio astronomical interferometry. This project will directly measure the size of the emission regions in a set of pulsars, and hence resolve the 40-year old debate regarding the s ....Testing pulsar emission models and general relativity at pico arcsecond resolution. A holographic technique has been pioneered that harnesses scattering in interstellar space to resolve the emission from pulsars at a resolution of 50 pico-arcseconds, six orders of magnitude finer than has been achieved by conventional radio astronomical interferometry. This project will directly measure the size of the emission regions in a set of pulsars, and hence resolve the 40-year old debate regarding the site of their radio emission. The project will also apply the technique to binary pulsar systems to provide a new test of General Relativity.Read moreRead less
Controlling parametric instabilities in advanced GW detectors. This project aims to solve the problem of parametric instability in gravitational wave detectors to support an international large-scale physics experiment. The project is part of Australia’s participation in the new advanced LIGO (Laser Interferometer Gravitational-Wave Observatory) gravitational wave detectors that have been designed to achieve the first detection of gravitational waves. A 2005 prediction made by the project leader ....Controlling parametric instabilities in advanced GW detectors. This project aims to solve the problem of parametric instability in gravitational wave detectors to support an international large-scale physics experiment. The project is part of Australia’s participation in the new advanced LIGO (Laser Interferometer Gravitational-Wave Observatory) gravitational wave detectors that have been designed to achieve the first detection of gravitational waves. A 2005 prediction made by the project leaders that the detectors would experience acoustic instabilities was confirmed during detector commissioning in 2014. The project team plans to work closely with the detector designers and commissioners to solve this problem and allow the detectors to achieve their target sensitivity.Read moreRead less
Extrinsic Control of Mammalian Germ Cell Delineation. Australia is a leader in the recent exciting breakthroughs in reproduction and development, such as cloning and embryonic stem cell propagation, and understanding how germ cells are specified would help us understand the biology underlying specification and developmental potential of all cells. This research will continue to contribute to maintaining Australia's high reputation in advances in reproductive biology. In addition, a greater under ....Extrinsic Control of Mammalian Germ Cell Delineation. Australia is a leader in the recent exciting breakthroughs in reproduction and development, such as cloning and embryonic stem cell propagation, and understanding how germ cells are specified would help us understand the biology underlying specification and developmental potential of all cells. This research will continue to contribute to maintaining Australia's high reputation in advances in reproductive biology. In addition, a greater understanding of marsupial reproduction is a high priority for Australia in the 21st century, with its current unacceptably high rate of mammalian extinctions, for 'we cannot conserve until we comprehend' (Short, 1985).The results therefore are of great potential benefit to society.
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Psychosocial and economic impacts of rare diseases on Australian children, families and health professionals. Rare childhood diseases have enormous impacts on children and families; health services, and health professionals. This project will enable Australia to lead the international research effort by using a coordinated approach to study the impacts of rare diseases in order to improve psychosocial, health and economic outcomes for children and families.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100008
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
Australian Seismic Imaging Array. The project aims to create a facility for developing techniques for imaging the deep earth and the surface motion in ambient seismic waves created by wind, waves and human activity. The techniques will enable sources of seismic vibrations to be identified and suppressed, and will allow mapping techniques to be developed for monitoring and discovery of resources such as ground water. Gravitational wave researchers will benefit from the ability to suppress seismic ....Australian Seismic Imaging Array. The project aims to create a facility for developing techniques for imaging the deep earth and the surface motion in ambient seismic waves created by wind, waves and human activity. The techniques will enable sources of seismic vibrations to be identified and suppressed, and will allow mapping techniques to be developed for monitoring and discovery of resources such as ground water. Gravitational wave researchers will benefit from the ability to suppress seismic vibrations, while geophysicists will benefit from new techniques and training. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100129
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
Equipment and instrumentation for breaking the quantum measurement barrier. This equipment will support Australia's partnership in the international effort to detect gravitational waves, which would allow the first direct observation of black holes and mark the beginning of exploration of the gravitational wave spectrum.
Three-Mode interactions and optical springs in high power optical cavities. Gravitational waves are tiny vibrations of space and time which carry vast energy. They will allow the first direct observation of black holes. To make frequent detections this project will harness the force of intense laser light, and use this force to improve the sensitivity of gravitational wave detectors.