Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The pr ....Is Calcium part of the mechanism used in glucose signalling in embryogenesis. A vital stage in the development of the embryo is formation of the blastocyst about 4 days after conception. For this to happen the embryo must receive glucose from the mother. We believe that rather being used by the embryo to generate energy, this glucose acts as a signal to switch on the developmental pathway leading to blastocyst formation. Without this signal there is no blastocyst and the pregnancy fails. The project investigates this signal mechanism. The results will advance understanding of the mechanisms regulating development and in particular link the mother's nutritive status to her fertility during very early pregnancy.Read moreRead less