The Role Of Protein Oxidation And Isomerization Pathways In The Pathogenesis Of Neisseria Meningitidis
Funder
National Health and Medical Research Council
Funding Amount
$264,816.00
Summary
Neisseria meningitidis causes meningococcal disease. It lives on the surface of the nasopharynx and in certain circumstances, can invade into the bloodstream causing sepsis. This is a complicated process, which involves many proteins produced by the bacteria. Many of these proteins contain a special covalent bond, the disulphide bond, which allows them to function properly. We are investigating how these disulphide bonds are put into proteins.