The Assessment And Treatment Of Cardiovascular Risk Factors,diabetes And Insulin Resistance In Polycystic Ovary Syndrome
Funder
National Health and Medical Research Council
Funding Amount
$304,047.00
Summary
Cardiovascular disease (CVD) and Type II Diabetes Mellitus (T2DM) are major health burdens in Australia. T2DM is increased and CVD may be increased in polycystic ovary syndrome (PCOS), a condition present in 10% of women and 30% of obese reproductive aged women. We aim to explore risk factors for CVD and T2DM in women with PCOS and to assess the effect of treatment strategies on metabolic and reproductive features in PCOS. This is crucial for reducing disease risk in this common condition.
Adrenal Cushings:natural History And Genetic Analysis Of Inherited Forms, And Prevalence In High Risk Groups.
Funder
National Health and Medical Research Council
Funding Amount
$100,381.00
Summary
This study aims to diagnose early Cushing's in certain high risk groups - before debilitating complications have developed which increase mortality. Early treatment normalises life expectancy and improves quality of life. We aim to discover the genetic cause of inherited Cushing's. This will allow a genetic test to be developed - so gene carriers can be carefully followed for onset of symptoms of Cushing's and those who are not carriers can be reassured.