Synthetic and theoretical studies of metal complexes containing carbon-rich ligands. Previous studies in my group, in conjunction with synthetic and theoretical chemistry groups at the Université de Rennes 1, France, have delineated the properties of a series of complexes containing carbon chains linking two metal centres. Having achieved a partial understanding of the features which result in good electronic communication between the metal centres via the carbon chain, the present proposal see ....Synthetic and theoretical studies of metal complexes containing carbon-rich ligands. Previous studies in my group, in conjunction with synthetic and theoretical chemistry groups at the Université de Rennes 1, France, have delineated the properties of a series of complexes containing carbon chains linking two metal centres. Having achieved a partial understanding of the features which result in good electronic communication between the metal centres via the carbon chain, the present proposal seeks to extend this collaboration to further studies which will generate related compounds in which actual eletron exchange can occur, i.e. leading to oxidation/reduction, by using compounds in which two or more different metal centres are present. This may lead to development of nano devices, e.g. molecular-scale switches. If one of the centres is activated by light, a photo-active sensor may result.Read moreRead less
Studies of metal compounds containing carbon chains - approaches to novel materials. There is an increasing need to design functional devices on the molecular scale ("nanotechnology"). We are developing the chemistry of compounds which contain chains of up to 12 carbon atoms to allow electronic communication between metal centres attached to each end. This projects seeks to extend this work, to discover new and more effective compounds, and to develop the associated chemistry to provide synthese ....Studies of metal compounds containing carbon chains - approaches to novel materials. There is an increasing need to design functional devices on the molecular scale ("nanotechnology"). We are developing the chemistry of compounds which contain chains of up to 12 carbon atoms to allow electronic communication between metal centres attached to each end. This projects seeks to extend this work, to discover new and more effective compounds, and to develop the associated chemistry to provide syntheses of novel compounds of potential use in the fine chemicals industry. Extensive collaboration with French colleagues exists and will continue.Read moreRead less
All-carbon molecules in metal complexes - novel materials and intermediates. An important requirement for the future is new materials with unusual properties that can be controlled. The need for ever smaller electronic devices requires knowledge about appropriate properties (particularly electronic) of molecules designed to model devices such as wires, switches, etc. This work seeks to design, measure and evaluate such molecules, which are based on chains of carbon atoms linking metal centres ....All-carbon molecules in metal complexes - novel materials and intermediates. An important requirement for the future is new materials with unusual properties that can be controlled. The need for ever smaller electronic devices requires knowledge about appropriate properties (particularly electronic) of molecules designed to model devices such as wires, switches, etc. This work seeks to design, measure and evaluate such molecules, which are based on chains of carbon atoms linking metal centres which can gain or lose electrons readily. As the electronic structure changes, so do the physical (photo, solid-state) and chemical properties (reactivity). Improved understanding of these features will benefit development of advanced technology and new materials.Read moreRead less
Universal immunogenic reagents for the detection of latent fingermarks. This project will deliver the first antibody reagents for the routine detection of natural fingermarks. This will assist law enforcement agencies to provide a safer society through improved crime clearance, as they will be able to enhance and detect fingermarks that otherwise remain undetected with current techniques (e.g. fingermarks on human skin).
Mechanisms for Pyrite Oxidation Control in Acid Mine Drainage. The annual costs of acid rock drainage (ARD) management at operating sites in Australia are $120M p.a.; over 15 years, a total cost of $1.8 billion for the whole industry. There are limitations to the ability of existing systems to cope with high capacity ARD, to the long-term effectiveness of these systems and high potential costs/liability of remediation. The value of the project outcomes to industry and government will be in reduc ....Mechanisms for Pyrite Oxidation Control in Acid Mine Drainage. The annual costs of acid rock drainage (ARD) management at operating sites in Australia are $120M p.a.; over 15 years, a total cost of $1.8 billion for the whole industry. There are limitations to the ability of existing systems to cope with high capacity ARD, to the long-term effectiveness of these systems and high potential costs/liability of remediation. The value of the project outcomes to industry and government will be in reduction of ARD release, well-understood long-term outcomes, reduced cost of treatments and improved control. The scale of these savings is in the tens of $M p.a. but also in potential improvements in environment (acid and toxic metals in streams), health and social quality of life in mining areas and towns.Read moreRead less
Evaluation of reaction mechanisms and products in acid rock drainage treatments. There are more than 54 sites in Australia managing major ARD wastes (either >10% of the waste or >10M tonnes) with another 62 sites with less ARD. At operating sites, the annual costs are $60M p.a.; over 15 years, a total cost of $900M for the whole industry. The value of the project outcomes to industry (and government) in reduction of acid and toxic metal release and reduced cost of treatments is potentially in th ....Evaluation of reaction mechanisms and products in acid rock drainage treatments. There are more than 54 sites in Australia managing major ARD wastes (either >10% of the waste or >10M tonnes) with another 62 sites with less ARD. At operating sites, the annual costs are $60M p.a.; over 15 years, a total cost of $900M for the whole industry. The value of the project outcomes to industry (and government) in reduction of acid and toxic metal release and reduced cost of treatments is potentially in the tens of $M p.a.. Improvements in environmental and social quality of life in mining areas and towns will also result from improved treatment.Read moreRead less
Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lip ....Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.Read moreRead less
Towards a Molecular-Scale Understanding of Sorption of Organic Pollutants to Soil. The toxicity, mobility and persistence of organic pollutants in soils are in large part controlled by their sorption to soil organic matter. The chemical nature or quality of the organic matter affects not only the amount of chemical sorbed, but also the reversibility of sorption and the rate of sorption and desorption. Until now, only bulk measures of soil organic matter chemistry have been considered in sorption ....Towards a Molecular-Scale Understanding of Sorption of Organic Pollutants to Soil. The toxicity, mobility and persistence of organic pollutants in soils are in large part controlled by their sorption to soil organic matter. The chemical nature or quality of the organic matter affects not only the amount of chemical sorbed, but also the reversibility of sorption and the rate of sorption and desorption. Until now, only bulk measures of soil organic matter chemistry have been considered in sorption studies. This project introduces novel spectroscopic techniques that for the first time identify the chemical environment of sorbed molecules at the molecular scale. This will enable better prediction of pollutant transport and degradation.Read moreRead less
Short- and long-term mitigation strategies for acid and metalliferous drainage control from iron ore mine wastes. Acid and metalliferous drainage from mine wastes, caused by oxidation of sulfide minerals, particularly pyrite, are a critical environmental issue worldwide. Although options to retard sulfide oxidation exist, including encapsulation methods, chemical additives and inhibition of iron-oxidising bacteria, these suffer from long-term instability. The project aims to investigate mechanis ....Short- and long-term mitigation strategies for acid and metalliferous drainage control from iron ore mine wastes. Acid and metalliferous drainage from mine wastes, caused by oxidation of sulfide minerals, particularly pyrite, are a critical environmental issue worldwide. Although options to retard sulfide oxidation exist, including encapsulation methods, chemical additives and inhibition of iron-oxidising bacteria, these suffer from long-term instability. The project aims to investigate mechanistic approaches, using readily available mineralogical materials, to provide passivating conditions resulting in slowed oxidation rates. The project’s focus is on treatments for wastes from iron ore deposits which are of high economic significance to Australia. The outcome aims to be a treatment ‘pathway’ enabling practical waste rock treatment over the acid forming time-profile.Read moreRead less
Long-term acid rock and tailings drainage mitigation through source control. Effective long-term management of acid rock drainage (ARD) from sulfidic mine wastes in current, exhausted and legacy mine sites is of critical importance to communities and for sustainable mining. An optimised geochemical and microbial multi-barrier approach to long-term reduction of ARD to environmentally acceptable rates will be developed by this project.