Psychiatric Disorders, Psychotropic Agents And Bone Health: From Benchtop To Bedside.
Funder
National Health and Medical Research Council
Funding Amount
$447,744.00
Summary
Just under half of all people with a psychiatric disorder have a chronic physical illness. One common and neglected comorbidity is osteoporosis. Dr Williams has brought together a multi-disciplinary team of researchers and clinicians that are gathering laboratory through to clinical evidence regarding the interplay between psychiatric disorders, the medication used to treat these disorders and bone health with the aim of informing clinical practice and guiding clinical choice.
Inflammatory Cytokines As Risk Factors For The Development Of Both Depression And Osteoporosis In Men
Funder
National Health and Medical Research Council
Funding Amount
$381,091.00
Summary
Both depression and osteoporosis impose a substantial public health burden on society and there is now research to suggest that these conditions are related. This study will examine a potential common mechanism, systemic inflammation, which may underlie both diseases. It will focus on markers of systemic inflammation, examine their association to both depression and bone fragility and determine what role they play in explaining the relationship between the disorders.
It is widely accepted that just under half of all people with bipolar disorder have a chronic physical illness. The one neglected comorbidity is osteoporosis. In this project, the association between bipolar disorder and bone fragility will be examined. Additionally, a potential common mechanism, systemic inflammation, which may underlie both diseases, will be investigated as a potential mediator of the relationship.