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Prediction Of Oral Appliance Treatment Outcome In Obstructive Sleep Apnoea
Funder
National Health and Medical Research Council
Funding Amount
$280,200.00
Summary
Obstructive sleep apnoea (OSA) is a very common disorder, affecting approximately 2% of women and 4% of men in the middle-aged workforce . It is characterised by repetitive, complete or partial closure of the throat passage during sleep, resulting in sleep disturbance and low oxygen levels. OSA is recognised as a serious public health problem. There is growing evidence supporting the use of oral appliances to treat OSA. It is thought that these work by enlarging the throat passage, but this rema ....Obstructive sleep apnoea (OSA) is a very common disorder, affecting approximately 2% of women and 4% of men in the middle-aged workforce . It is characterised by repetitive, complete or partial closure of the throat passage during sleep, resulting in sleep disturbance and low oxygen levels. OSA is recognised as a serious public health problem. There is growing evidence supporting the use of oral appliances to treat OSA. It is thought that these work by enlarging the throat passage, but this remains uncertain. The aim of this project is to gain a better understanding of how such appliances work, so as to be able to predict which patients will particularly benefit from this form of treatment.Read moreRead less
The Impact Of Declining Tooth Loss On Oral Health Status And Dental Care Utilisation
Funder
National Health and Medical Research Council
Funding Amount
$144,375.00
Summary
Improved oral health has been well documented in Australia. Over recent decades the average number of decayed teeth among children has decreased. Among adults, the percentage with no natural teeth has also exhibited a decrease over time. While increased retention of natural teeth is an indicator of improved oral health status within the population, there may be some unexpected consequences of this success. Improved oral health has been associated with increased rather then decreased use of servi ....Improved oral health has been well documented in Australia. Over recent decades the average number of decayed teeth among children has decreased. Among adults, the percentage with no natural teeth has also exhibited a decrease over time. While increased retention of natural teeth is an indicator of improved oral health status within the population, there may be some unexpected consequences of this success. Improved oral health has been associated with increased rather then decreased use of services. Improvements in oral health manifested in the form of greater tooth retention, coupled with demographic trends towards growth in the population, may lead to an increased risk of oral disease with flow on effects on need and demand for care. Findings from one cross-sectional study in the USA have shown that people who retained higher numbers of teeth had more periodontal disease and dental caries experience, and reported a past pattern of visiting the dentist more frequently. The specific aims of this project are to examine the association of the number of natural teeth among middle-aged Australians with their oral health status, treatment needs and subsequent use of dental services. The outcome of this project will provide answers to two research questions. Firstly, it will see whether the retention of more teeth among adults is associated with higher levels of oral disease. Secondly, by following people over time it will be able to detect whether those who are retaining more teeth into adult age ranges have higher levels of use of dental services than their counterparts with fewer teeth. The answers to both of these research questions has significance for policy and planning in the area of dental public health by providing evidence as to the size and direction of expected future demand for and use of dental services in Australia.Read moreRead less
Randomised Control Trial Of Effectiveness Of Silver Fluoride In Managing Deciduous Dental Caries In Remote Aboriginal Communities
Funder
National Health and Medical Research Council
Funding Amount
$695,220.00
Summary
This study seeks to test a non-invasive treatment for dental decay in young children which may prevent the progression of the decay further into the tooth. This treatment is currently used in some areas. Dental decay is very common in young children in remote communities where access to dental care is often limited. The treatment may reduce pain and oral and facial infections sometimes leading to hospitalisation.
Bisphosphonate Use, Oral Flora, Saliva, Gingival Crevicular Fluid And Bone Markers In Patients With Jaw Osteonecrosis
Funder
National Health and Medical Research Council
Funding Amount
$121,751.00
Summary
Bisphosphonates are used in patients with bones that break easily due to conditions such as osteoporosis. Recent research suggests a possible association between these drugs and jaw bone breakdown called jaw osteonecrosis - a devastating condition with no current effective treatment. It is unclear why this condition affects only jaw bones. This study seeks to investigate if bacteria in the mouth, gum disease and saliva are involved in jaw osteonecrosis, which can then help to improve management.
The CCRE for Oral Health will focus on the prevention and treatment of oral diseases and disorders and their clinical consequences. Research will emphasise three areas of clinical care that are critical to the management of oral health, systemic health and general well-being: 1.Primary prevention to prevent disease onset 2. Diagnosis and risk prediction for oral conditions 3. Clinical intervention
Caries Initiation Across Childhood To Adulthood By Exposure To Water Fluoridation
Funder
National Health and Medical Research Council
Funding Amount
$198,297.00
Summary
This research program is expected to contribute to filling significant gaps in the understanding of factors determining the oral health of Australian children and young adults. The purpose of the project is to develop a better understanding of the outcome of long-term exposure to fluoridated water among young adults.
The South Australian Dental Longitudinal Study has been the first comprehensive dental longitudinal study of older adults to be conducted in Australia. Participants were aged 60+ years at the 1991 baseline data collection, and were a random sample of community-dwelling older adults in urban Adelaide and rural Mount Gambier. The 11-year follow-up data collection will build upon the previous study findings to provide important and new information about the onset and progression of oral diseases in ....The South Australian Dental Longitudinal Study has been the first comprehensive dental longitudinal study of older adults to be conducted in Australia. Participants were aged 60+ years at the 1991 baseline data collection, and were a random sample of community-dwelling older adults in urban Adelaide and rural Mount Gambier. The 11-year follow-up data collection will build upon the previous study findings to provide important and new information about the onset and progression of oral diseases in older Australians. It will also assist with the identification of general health and other characteristics (socio-demographic, medical, functional, cognitive, nutritional, swallowing, dental history, oral hygiene care, financial, social support and oral disorder social impact characteristics) that are associated with oral diseases in various groups of older adults. Groups of older adults within the study include those who are healthy and living in the community, those who are frail and use support services, and those who have moved into residential care. This information will assist both private and public health sectors, dental professionals and other health professionals with the identification of those older adults who are at high risk for developing oral diseases, such as those with dementia, those with physical disabilities, and those living in residential care. This 11-year data collection will be one of only 4 similar international studies currently being conducted, and will provide important comparison data for future studies of older Australians.Read moreRead less
Squamous Cell Carcinomas Of The Head And Neck: Exploring The Role Of Human Papillomavirus Infection
Funder
National Health and Medical Research Council
Funding Amount
$217,213.00
Summary
Human papillomavirus (HPV) is the major cause of cervical cancer and the cause of 5% of all human cancers. HPV has recently also been associated with oral cancer, especially in patients younger than 50 years of age. In this project we will investigate how common HPV infection is in oral cancers in Australia. In these patients we will also investigate mutations in genes that have been found to play a critical role to clear persistent HPV infections and how cells respond to HPV infection.