Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directiona ....Relationship of retinal directionality to human retinal anatomy variations. This project aims to improve measurement of retinal directionality, which is the reduction in brightness when a light beam’s entry into the human eye is shifted from the centre to the edge of the pupil. This influences retinal image quality and can be used to measure changes in shape of the peripheral eye. This project will apply advanced technologies in holography, and heads-up displays to explore how retinal directionality changes during accommodation (focusing). The expected outcome is improved understanding of retinal stretching changes during focusing. The benefit is that the project will lead to advancements in retinal imaging.Read moreRead less
Removing the blinkers: a wider study of the human eye. Peripheral aberrations, wide-field retinal imaging and optical parameters. This project will study peripheral (side vision) optics of the human eye and its role in the limits of visual performance. This will improve ocular measurements and contribute towards improved diagnosis and treatment of ocular diseases and short-sightedness.
Advanced methods for intraocular imaging. The ability to image the retina of the human eye at high resolution is fundamental to improving understanding of ocular physiology, ocular optics and disease diagnosis. This project applies the relatively new application of active optics to vision science. This project will investigate the advantages of using new beam shaping techniques for characterising the optics of the eye, improving retinal imagery and improving fixation stability. This project will ....Advanced methods for intraocular imaging. The ability to image the retina of the human eye at high resolution is fundamental to improving understanding of ocular physiology, ocular optics and disease diagnosis. This project applies the relatively new application of active optics to vision science. This project will investigate the advantages of using new beam shaping techniques for characterising the optics of the eye, improving retinal imagery and improving fixation stability. This project will achieve three-dimensional holography of human eyes and develop holography plates for correcting the aberrations of eyes. Expected outcomes are not-before experienced resolution images of the retina and better understanding of the optical characteristics of the refractive surfaces and media in the eye.Read moreRead less
Do sex steroids regulate tear lipid production in human meibomian glands? This project aims to determine whether production of tear film lipids by meibomian gland cells is regulated by sex steroids. The tear film is essential to eyesight. It protects and nourishes the eye surface to maintain transparency to enable light to reach the retina. To guarantee these functions, exquisite control of tear film composition is required, including the outer lipid layer. Sex hormones, including oestrogen, may ....Do sex steroids regulate tear lipid production in human meibomian glands? This project aims to determine whether production of tear film lipids by meibomian gland cells is regulated by sex steroids. The tear film is essential to eyesight. It protects and nourishes the eye surface to maintain transparency to enable light to reach the retina. To guarantee these functions, exquisite control of tear film composition is required, including the outer lipid layer. Sex hormones, including oestrogen, may control production of the lipid layer by meibomian glands in the eyelid, but this has not been confirmed in humans. This project aims to show whether meibomian glands produce sex hormones, which then control production of tear lipids. This new knowledge will improve our understanding of how the tear film maintains clear vision.Read moreRead less