Design and Analysis of Optimal Algorithms for Automated Perimetry. Australian demographic studies reveal that visual impairment contributes significantly to disability in the elderly. Glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, however recent studies estimate 50% of Australians with glaucoma are undiagnosed. Automated perimetry is used to detect and track such vision loss, but perimetry algorithms perform poorly. This project will design ....Design and Analysis of Optimal Algorithms for Automated Perimetry. Australian demographic studies reveal that visual impairment contributes significantly to disability in the elderly. Glaucoma, the second leading cause of blindness in developed nations, may be slowed if detected early, however recent studies estimate 50% of Australians with glaucoma are undiagnosed. Automated perimetry is used to detect and track such vision loss, but perimetry algorithms perform poorly. This project will design and analyse new algorithms with superior accuracy and efficiency, improving detection and monitoring of vision loss. Enhanced tools for community vision screening will also result, crucial for the ARC's priority goals of ?ageing well, ageing productively? and ?preventative healthcare?Read moreRead less
A comparative study of the laser-tissue interaction between solid state 213nm vs excimer gas 193nm laser systems. We will carry out a comparative study of the latest technological developments in laser vision correction surgery. We will compare the biological effects of a new solid state laser operating at 213nm and a traditional excimer gas laser operating at 193nm. For each laser type, long-term scarring, cytotoxicity, mutagenicity and free radical production will be studied in relevant in viv ....A comparative study of the laser-tissue interaction between solid state 213nm vs excimer gas 193nm laser systems. We will carry out a comparative study of the latest technological developments in laser vision correction surgery. We will compare the biological effects of a new solid state laser operating at 213nm and a traditional excimer gas laser operating at 193nm. For each laser type, long-term scarring, cytotoxicity, mutagenicity and free radical production will be studied in relevant in vivo and in vitro animal models. Furthermore, optimization of the irradiation protocol for the solid state laser will lead to the development of a wide range of biological applications.Read moreRead less