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Renal Artery Denervation Performed With Noncontact Circumferential Endovascular Ablation Using A Novel Microwave Catheter
Funder
National Health and Medical Research Council
Funding Amount
$90,967.00
Summary
High blood pressure is a common medical condition leading to death and disability. Some people with high blood pressure do not respond to medical treatment due to abnormal signals from the kidneys that tell the body to increase the blood pressure. We have designed a microwave catheter that can be placed inside the kidney artery and used to heat the kidney nerves around it to stop the relay of these messages. This will lower blood pressure for people who cannot control it with medications alone.
Mechanisms Of Retinal Functional Hyperaemia In Humans With And Without Type 1 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$117,526.00
Summary
Fenofibrate has been shown to reduce the progression of diabetic retinopathy (DR) in patients with type 2 diabetes by up to 40%, however the mechanisms behind this result are poorly understood. This research will investigate measures of local and systemic endothelial dysfunction and levels of lipids and lipoproteins to determine how fenofibrate affects the progression of DR in patients with type 2 diabetes and in doing so form the basis of further basic and clinical research.
Molecular Basis For Female Age-associated Decline In Oocyte Quality And Fertility
Funder
National Health and Medical Research Council
Funding Amount
$71,792.00
Summary
Many women cannot have children because of suboptimal egg quality, often due to ageing. In order for novel strategies to be developed for improving egg quality, it will first be important to understand how key factors in eggs are regulated. This project will use state-of-the-art techniques to interrogate a pivotal pathway we have discovered in eggs that could be responsible for age-related decline and could hold the key to new approaches for rejuvenating eggs.
An Exploration Of Cerebral Palsy Aetiology: Assisted Reproductive Technology And Congenital Anomalies
Funder
National Health and Medical Research Council
Funding Amount
$89,420.00
Summary
Cerebral palsy (CP) is the most common physical disability of childhood, describing a group of permanent disorders of movement caused by damage to the developing brain. The causes of CP are poorly understood for most people. This study will explore and quantify the impact of two known risk factors on CP: assisted reproductive technology and congenital anomalies. When these causes of CP are better understood, possibilities for prevention of this disability can be sought.