Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understandi ....Dynamic Mechano-Microscopy for use in Mechanobiology . We will develop an innovative microscope that will enable new discoveries in biology. Most microscopes form images of a sample's optical properties, instead we will image a sample's mechanical properties. The reason our novel approach is needed is that cell behaviour depends on the stiffness of it's environment, but current microscopes are unable to image this. Our microscope will provide insights in biology that can improve our understanding of cells, the building blocks of life. We will achieve this by: 1. Developing a microscope that combines microscopic resolution with rapid imaging; 2: Developing the capability to image both within the cell and its surrounding environment; and 3. Using our microscope to make discoveries in biology.Read moreRead less
Control of Instabilities in Advanced Gravitational Wave Detectors. Gravitational wave technology from UWA has already given rise to significant spin-offs including sapphire oscillators for radar applications and vibration isolators for airborne mineral exploration. This project will lead to techniques for increasing the sensitivity of already extraordinary sensitive instruments, and could have applications in many areas. The project will strengthen Australia's role in the world wide quest to det ....Control of Instabilities in Advanced Gravitational Wave Detectors. Gravitational wave technology from UWA has already given rise to significant spin-offs including sapphire oscillators for radar applications and vibration isolators for airborne mineral exploration. This project will lead to techniques for increasing the sensitivity of already extraordinary sensitive instruments, and could have applications in many areas. The project will strengthen Australia's role in the world wide quest to detect gravitational waves, which is one of the most significant and challenging human endeavours. The project will use the superb national research facility at Gingin. Its content contributes to the Eureka Prize winning Gravity Discovery Centre also located at the site, which is a major centre for science education.Read moreRead less
In vivo mechano-microscopy: a discovery platform for cell mechanics. This project aims to develop a platform for quantitative 3-D imaging of cell elasticity in tissue which may make possible new discoveries in cell mechanics. Mechanical properties, in concert with chemical properties, act to determine the function and behaviour of cells, and play a vital role in diseases such as cancer. Measurement of the mechanical properties of the cell in its native tissue environment, currently not possible, ....In vivo mechano-microscopy: a discovery platform for cell mechanics. This project aims to develop a platform for quantitative 3-D imaging of cell elasticity in tissue which may make possible new discoveries in cell mechanics. Mechanical properties, in concert with chemical properties, act to determine the function and behaviour of cells, and play a vital role in diseases such as cancer. Measurement of the mechanical properties of the cell in its native tissue environment, currently not possible, could accelerate the understanding of cell mechanics. This project plans to develop in vivo mechano-microscopy by combining innovations in optical microscopy, micro-mechanical loading, and computational methods. It then plans to demonstrate its capability by producing the first 3-D elasticity maps of skeletal muscle cells in living animals.Read moreRead less
Experiments with Advanced Isolation Systems, Suspension and Test Masses Using ACIGA's High Optical Power Test Facility. This proposal will allow experimental verification of the performcane of of sapphire test masses and their associated isolation and suspension system in ACIGA's high optical power test facility at Gingin. The work will contribute to the worldwide effort to increase the sensitivity of laser interferometers to the level where known sources of gravitational waves can be detected ....Experiments with Advanced Isolation Systems, Suspension and Test Masses Using ACIGA's High Optical Power Test Facility. This proposal will allow experimental verification of the performcane of of sapphire test masses and their associated isolation and suspension system in ACIGA's high optical power test facility at Gingin. The work will contribute to the worldwide effort to increase the sensitivity of laser interferometers to the level where known sources of gravitational waves can be detected at a reasonable rate.Read moreRead less
Worldwide Collaboration for the Creation of New Frequency Standards, and their Application to testing the Foundations of Physics. Frequency standards are crucial for the highest precision scientific measurements as well as in modern communication and information technology (C&IT). Having already achieved world-best performance for short-term frequency stability, our research team is seeking support to participate in a broad international program with three particular objectives:
(i) create ne ....Worldwide Collaboration for the Creation of New Frequency Standards, and their Application to testing the Foundations of Physics. Frequency standards are crucial for the highest precision scientific measurements as well as in modern communication and information technology (C&IT). Having already achieved world-best performance for short-term frequency stability, our research team is seeking support to participate in a broad international program with three particular objectives:
(i) create new frequency standards based on laser-cooled atoms,
(ii) develop femtosecond laser technology for generating low noise microwave and optical signals,
(iii) develop microwave technology suitable for operation in space.
Improved frequency standards will allow decisive measurements on several fundamental scientific questions, as well as leading to commercial applications in C&IT.
Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989747
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Ultrafast Dynamics Measurement Facility for the Physical, Biochemical, and Materials Sciences. The term "ultrafast revolution" describes the transformations in science due to ultrafast laser technology. Today, ultrafast lasers are used in surgery, nanomaterial fabrication, biomedical imaging, spectroscopic investigations, and new applications are still emerging. This facility will draw together leading chemists, physicists, and engineers to investigate key ultrafast processes and phenomena in th ....Ultrafast Dynamics Measurement Facility for the Physical, Biochemical, and Materials Sciences. The term "ultrafast revolution" describes the transformations in science due to ultrafast laser technology. Today, ultrafast lasers are used in surgery, nanomaterial fabrication, biomedical imaging, spectroscopic investigations, and new applications are still emerging. This facility will draw together leading chemists, physicists, and engineers to investigate key ultrafast processes and phenomena in the physical, biochemical and material sciences. This is of strategic importance to keep Australia at the global forefront for scientific endeavours, supporting new research and commercial opportunities. This facility will also produce highly trained graduates, who will find employment in industry throughout Australia and globally.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100099
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
A complete near-field scanning optical microscope for advanced characterisation of novel and functional materials. This near-field optical scanning microscope will be unique in Australia and will substantially enhance national research capabilities in functional materials, nanotechnology, biotechnology and chemistry. It will create a platform to advance Australian research to new levels in pharmaceuticals, nanomaterials and energy storage materials.
International collaboration in gravitational wave data analysis, simulations and third generation detectors. The project brings together seven outstanding international researchers into close collaboration with an Australian team to develop new techniques for finding gravitational wave signals in the vast archive of data they have helped to collect, as well as developing and testing theory for improved detectors that operate with sensitivity beyond the limits set by classical physics. The projec ....International collaboration in gravitational wave data analysis, simulations and third generation detectors. The project brings together seven outstanding international researchers into close collaboration with an Australian team to develop new techniques for finding gravitational wave signals in the vast archive of data they have helped to collect, as well as developing and testing theory for improved detectors that operate with sensitivity beyond the limits set by classical physics. The project will utilize a state of the art supercomputer and the superb national facility for high power laser interferometry at Gingin, Western Australia. Read moreRead less
Precision measurement to test fundamental physics. This project gives the University of Western Australia the opportunity to lead some of the world's best tests on fundamental physics by implementing their novel precision technology. It will also strengthen their collaboration between elite metrological institutes, including Paris Observatory, Ecole Normale Superior and Humboldt University.
Developing New Clocks for Australia: Testing the Assumptions of Modern Physics. Clocks lie at the heart of all precise measurement devices; for example, they are the crucial elements in modern navigation and telecommunications systems. This project will develop three new clocks for Australia: a laser clock at the leading edge of technology, a novel and compact clock with commercial potential, and a microwave clock for use in the next generation of satellites. The performance advantage conferre ....Developing New Clocks for Australia: Testing the Assumptions of Modern Physics. Clocks lie at the heart of all precise measurement devices; for example, they are the crucial elements in modern navigation and telecommunications systems. This project will develop three new clocks for Australia: a laser clock at the leading edge of technology, a novel and compact clock with commercial potential, and a microwave clock for use in the next generation of satellites. The performance advantage conferred by our new devices can deliver economic benefits while also giving the possibility for scrutinizing the laws of physics for evidence that there is something beyond our present formulation.Read moreRead less