Optically-driven micromachines and microtools. The use of optical forces to trap and manipulate microscopic particles has developed from a novelty into a widely used versatile research tool - optical tweezers. New advances, such as the application and optical measurement of optical torque, have been brought to the brink of practical application. We will apply these methods to the development and production of micromachines of unprecedently small size, and the development of new medical diagnosti ....Optically-driven micromachines and microtools. The use of optical forces to trap and manipulate microscopic particles has developed from a novelty into a widely used versatile research tool - optical tweezers. New advances, such as the application and optical measurement of optical torque, have been brought to the brink of practical application. We will apply these methods to the development and production of micromachines of unprecedently small size, and the development of new medical diagnostic techniques, and industrial and research tools.Read moreRead less
Probing new physics with atomic parity violation. This project aims to provide a new level of rigour in tests of the standard model of particle physics at low energies, and to reveal or more tightly constrain new particles or forces. This will involve the development of state-of-the-art atomic theory techniques and collaboration with world-leading experimental groups. The expected outcomes and benefits include a breakthrough in the precision of atomic theory calculations, new insights into nucle ....Probing new physics with atomic parity violation. This project aims to provide a new level of rigour in tests of the standard model of particle physics at low energies, and to reveal or more tightly constrain new particles or forces. This will involve the development of state-of-the-art atomic theory techniques and collaboration with world-leading experimental groups. The expected outcomes and benefits include a breakthrough in the precision of atomic theory calculations, new insights into nuclear magnetic structure, improved determination of fundamental particle physics parameters, stronger ties with the international experimental community, enhancing Australian leadership and expertise, and high-level training of the next generation of scientists.Read moreRead less
Control of light in space and time in multimode optical fibres. This project aims to create devices to measure and manipulate the spatial and temporal properties of light. The ability to control or measure the spatial and/or temporal properties of light is a fundamental feature of many applications, including biomedical imaging, astronomy, telecommunications, high-power lasers and quantum computing. This project will develop five prototype systems to control the spatiotemporal properties of ligh ....Control of light in space and time in multimode optical fibres. This project aims to create devices to measure and manipulate the spatial and temporal properties of light. The ability to control or measure the spatial and/or temporal properties of light is a fundamental feature of many applications, including biomedical imaging, astronomy, telecommunications, high-power lasers and quantum computing. This project will develop five prototype systems to control the spatiotemporal properties of light in ways that were previously not possible. This would affect fundamental and applied applications where the inability to sufficiently control light’s spatial and/or temporal properties is an impediment. Examples include imaging deep into ‘opaque’ objects such as human skin or brain, high-power lasers for material processing and manufacturing, optical telecommunications and quantum computation.Read moreRead less
Quantum coherence of electronic transport in layered magnetoresistive materials. The continued rapid expansion of information technology requires new materials and devices for information storage. State of the art computer memories are based on new materials which consist of layers of complex arrays of atoms. These materials have metallic properties quite unlike those of simple metals such as copper and steel. This research will lead to a greater understanding of and ability to design better ma ....Quantum coherence of electronic transport in layered magnetoresistive materials. The continued rapid expansion of information technology requires new materials and devices for information storage. State of the art computer memories are based on new materials which consist of layers of complex arrays of atoms. These materials have metallic properties quite unlike those of simple metals such as copper and steel. This research will lead to a greater understanding of and ability to design better materials. Australia's capacity for research and development in this scientifically challenging and technologically important field will be enhanced by this project. Read moreRead less
Biomolecular optoelectronic materials and devices. The melanins are the molecules in our skin, eyes and hair that provide colour and protection from the sun. In addition to being important bio-molecules, they have properties which make them useful for high tech applications especially in electronics and optoelectronics. Unfortunately, our current understanding of these fascinating materials is poor. In our project we aim to solve this limiting problem. We will develop new science to explain thei ....Biomolecular optoelectronic materials and devices. The melanins are the molecules in our skin, eyes and hair that provide colour and protection from the sun. In addition to being important bio-molecules, they have properties which make them useful for high tech applications especially in electronics and optoelectronics. Unfortunately, our current understanding of these fascinating materials is poor. In our project we aim to solve this limiting problem. We will develop new science to explain their behaviour, and use this knowledge to create bio-compatible hi-tech materials and devices. We anticipate significant benefits from the perspectives of basic science and utilisation of biomaterials for new green technologies.Read moreRead less
Sensing single electrons with single molecules. The focus of this project is on optical detection of single electron transport in solids and in large/bio molecules. Successful experimental demonstration of the proposed technique will considerably enhance Australia's standing in high profile areas of natural sciences. In practical terms, it can contribute to development of new generation solar cells, artificial photosynthetic centres, and a new generation of nanoprobes for biomedical application ....Sensing single electrons with single molecules. The focus of this project is on optical detection of single electron transport in solids and in large/bio molecules. Successful experimental demonstration of the proposed technique will considerably enhance Australia's standing in high profile areas of natural sciences. In practical terms, it can contribute to development of new generation solar cells, artificial photosynthetic centres, and a new generation of nanoprobes for biomedical applications. Because the single-molecule technique is a new and dynamic field, opportunities exist for significant commercial property development. The project will also train a number of students in several fields of high technology, all of which are likely to have high demand in the future.Read moreRead less
Intravital super-resolution imaging via Stimulated Emission Depletion microscopy (STED)-microendoscopy. We will develop a new technology to enable the imaging of sub-cellular structures within a biological specimen, with super-resolution. This intravital super-resolution imaging technology will build off world leading techniques to image objects with super-resolution and to perform this within a specimen, with minimal invasion. The broad ramifications of this technology apply to biology, medical ....Intravital super-resolution imaging via Stimulated Emission Depletion microscopy (STED)-microendoscopy. We will develop a new technology to enable the imaging of sub-cellular structures within a biological specimen, with super-resolution. This intravital super-resolution imaging technology will build off world leading techniques to image objects with super-resolution and to perform this within a specimen, with minimal invasion. The broad ramifications of this technology apply to biology, medical science, imaging and sensing. Important applications include the early detection of debilitating diseases and the advancement of understanding of cellular biology. This research will raise Australia's profile as a world leader in science and technology, building on our emerging presence in the biophysical sciences.Read moreRead less
Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanopart ....Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing. This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.Read moreRead less
Nanotechnology in nature: the evolutionary significance of iridescent ultraviolet colouration in butterflies. Nanostructural colour is a novel and interesting biological phenomenon that has potential application in textile and paint industries. This research has the potential to uncover knowledge relevant to future genetic manipulation and/or artificial synthesis of this trait for industry. Fundamental benefits will include a contribution to our understanding of evolution and biological diversit ....Nanotechnology in nature: the evolutionary significance of iridescent ultraviolet colouration in butterflies. Nanostructural colour is a novel and interesting biological phenomenon that has potential application in textile and paint industries. This research has the potential to uncover knowledge relevant to future genetic manipulation and/or artificial synthesis of this trait for industry. Fundamental benefits will include a contribution to our understanding of evolution and biological diversity, enhancement of Australia's research profile, and the cultivation of new scientific expertise. This proposal also promises to benefit the Australian scientific community through the establishment of collaborative links with universities in the USA and UK, and to increase mainstream awareness of Australia's stunning natural resources.Read moreRead less
Light scattering in complex mesoscale systems. The aim of the proposed project is to develop tested theoretic models of, and test applications of, the scattering of light in complex mesoscale systems. This will include: light scattering by biological cells, including optical cancer detection, remote sensing of cell populations, flow cytometry and optical tweezers; optically driven micromachines, and nano- and micro-structured materials. These applications are of considerable technological, socia ....Light scattering in complex mesoscale systems. The aim of the proposed project is to develop tested theoretic models of, and test applications of, the scattering of light in complex mesoscale systems. This will include: light scattering by biological cells, including optical cancer detection, remote sensing of cell populations, flow cytometry and optical tweezers; optically driven micromachines, and nano- and micro-structured materials. These applications are of considerable technological, social, and economic importance, and significant advances are possible. Methods developed during this project will allow accurate theoretical calculations to be performed where only inadequate approximations have previously been possible.Read moreRead less