Disruptive approaches to biological sensing. Optical fibre-based biosensors have the potential to transform our ability to monitor our environment, protect our nation's assets and safeguard our citizens, and to offer improved clinical diagnostics and food quality control by creating tools that can detect biomolecules in real-time within complex samples. To fulfil this mission, we propose to develop new fibre-based sensing architectures for sensing biomolecules that have the potential to be sensi ....Disruptive approaches to biological sensing. Optical fibre-based biosensors have the potential to transform our ability to monitor our environment, protect our nation's assets and safeguard our citizens, and to offer improved clinical diagnostics and food quality control by creating tools that can detect biomolecules in real-time within complex samples. To fulfil this mission, we propose to develop new fibre-based sensing architectures for sensing biomolecules that have the potential to be sensitive, selective, fast and compact.Read moreRead less
Transformational diagnostics. Australia has established world-leading capabilities in optical fibres and surface science that, when brought together, have the potential to transform applications that require non-invasive, real-time and/or portable biological detection tools. We propose a novel and ambitious suite of projects that bring together these capabilities with experts in reproductive health, forensics and explosives to solve pressing problems in each of these areas that have the promise ....Transformational diagnostics. Australia has established world-leading capabilities in optical fibres and surface science that, when brought together, have the potential to transform applications that require non-invasive, real-time and/or portable biological detection tools. We propose a novel and ambitious suite of projects that bring together these capabilities with experts in reproductive health, forensics and explosives to solve pressing problems in each of these areas that have the promise to develop into new industries for Australia as well as to explore rich science opportunities at the boundaries of these disciplines.Read moreRead less
Accretion and Feedback in Galaxies with Cosmic Time. Australia is a world leader in both astronomy and photonics. This proposal seeks to exploit a revolutionary device that is the first developed from the new cross-over field of astrophotonics. The Gemini Near-infrared OH Suppression IFU System (GNOSIS) instrument will showcase Australian industry development in optical fibres and will keep Australian astronomers at the forefront of international research. This will lead to major advantages wh ....Accretion and Feedback in Galaxies with Cosmic Time. Australia is a world leader in both astronomy and photonics. This proposal seeks to exploit a revolutionary device that is the first developed from the new cross-over field of astrophotonics. The Gemini Near-infrared OH Suppression IFU System (GNOSIS) instrument will showcase Australian industry development in optical fibres and will keep Australian astronomers at the forefront of international research. This will lead to major advantages when developing future instrumentation for next generation telescopes such at the Giant Magellan Telescope, enabling Australia to continue to lead astronomy and astronomical instrumentation into the next decade and beyond.Read moreRead less
Nanoimaging the cellular architecture of the malaria parasite, Plasmodium falciparum. The immediate benefit of this work will be in the understanding and treatment of malaria - a disease that kills approximately 1 million children annually. The ability to image the three-dimensional structure of cells at high resolution will allow us to ask fundamental questions about the cellular architecture of the malaria parasite and to design novel antimalarial strategies. By developing new methods for cor ....Nanoimaging the cellular architecture of the malaria parasite, Plasmodium falciparum. The immediate benefit of this work will be in the understanding and treatment of malaria - a disease that kills approximately 1 million children annually. The ability to image the three-dimensional structure of cells at high resolution will allow us to ask fundamental questions about the cellular architecture of the malaria parasite and to design novel antimalarial strategies. By developing new methods for correlating structure and elemental location, the work in this proposal will offer a new paradigm for the study of cellular function and disease. This represents an important advance in the suite of investigative tools available to the biotechology sector and will see a corresponding improvement in our understanding of a wide range of disease states.Read moreRead less
A New Era for Australian Exoplanetary Science. There are few areas of learning that engage the public in cutting-edge science and technology more than astronomy – and few areas of astronomy that engage and fascinate as thoroughly as the study of planets and astrobiology. This research program will not only discover new rocky and gas giant planets orbiting other stars, but tell us about how those planets formed – allowing us to answer the key question for current exoplanetary research – “Are ther ....A New Era for Australian Exoplanetary Science. There are few areas of learning that engage the public in cutting-edge science and technology more than astronomy – and few areas of astronomy that engage and fascinate as thoroughly as the study of planets and astrobiology. This research program will not only discover new rocky and gas giant planets orbiting other stars, but tell us about how those planets formed – allowing us to answer the key question for current exoplanetary research – “Are there other Earths in the Universe?”Read moreRead less
A fundamental study of electronic transport in advanced semiconductor nanostructures. The principal aim of this project is to attract and retain very high calibre early career researchers by providing them with the best-available infrastructure and research environment, combined with world-class supervision and mentoring. The project brings together an outstanding team of international collaborators, who will work with the early career researchers to ensure that they are trained and mentored at ....A fundamental study of electronic transport in advanced semiconductor nanostructures. The principal aim of this project is to attract and retain very high calibre early career researchers by providing them with the best-available infrastructure and research environment, combined with world-class supervision and mentoring. The project brings together an outstanding team of international collaborators, who will work with the early career researchers to ensure that they are trained and mentored at an international level. The new science, novel characterisation methods, and theoretical models that are outcomes of this project will provide new opportunities and expertise to advance the strategic defence and national security interests of Australia, and the emerging Australian semiconductor device and solar cell industry. Read moreRead less
Space Science and Astronomy: Dissecting the Galaxy with High Resolution Multi-Object Echelle Spectrograph (HERMES) II: Decisive Observations. Australia has long been a world leader in wide-field astronomical surveys, and the new High Resolution Multi-Object Echelle Spectrograph (HERMES) being built for the Anglo-Australian Telescope (AAT) will enhance that leadership position. Through a combination of Australian technological and scientific advances, the surveys we conduct with HERMES will allow ....Space Science and Astronomy: Dissecting the Galaxy with High Resolution Multi-Object Echelle Spectrograph (HERMES) II: Decisive Observations. Australia has long been a world leader in wide-field astronomical surveys, and the new High Resolution Multi-Object Echelle Spectrograph (HERMES) being built for the Anglo-Australian Telescope (AAT) will enhance that leadership position. Through a combination of Australian technological and scientific advances, the surveys we conduct with HERMES will allow us to study galaxy formation and stellar astrophysics in unprecedented detail. There are powerful synergies between HERMES and Skymapper, another Australian astronomical survey, as well as with Gaia, the billion-dollar European space mission for studying the Galaxy; HERMES will thus promote both national and international research collaboration. In this proposal we lay the observational groundwork for maximising the scientific return from HERMES.Read moreRead less
Space science and astronomy: New eyes on old stars: Decoding late-stage stellar evolution. Planetary nebulae, the extended shrouds of dying stars, are a fascinating, brief period in the life of most stars. Our Sun will eventually go through this phase engulfing the earth. Planetary nebulae are unique celestial laboratories thanks to their rich emission line spectra. They are amongst the most beautiful and mysterious of objects, whose startling images act as a photogenic magnet for public interes ....Space science and astronomy: New eyes on old stars: Decoding late-stage stellar evolution. Planetary nebulae, the extended shrouds of dying stars, are a fascinating, brief period in the life of most stars. Our Sun will eventually go through this phase engulfing the earth. Planetary nebulae are unique celestial laboratories thanks to their rich emission line spectra. They are amongst the most beautiful and mysterious of objects, whose startling images act as a photogenic magnet for public interest. Behind their beauty hides the mystery of how stars return carbon, one of life's essential building blocks - to interstellar space. This project will constitute the next major breakthrough in understanding these processes and addresses several significant astrophysical problems in the field via unique Australian data and instrumentation.Read moreRead less
Extreme expression: building a platform for industrial plant biotechnology. Plants have remarkable potential as bioreactors for the production of usually non-plant compounds such as medical proteins, industrial proteins including enzymes and polymers. However, to realise this potential, there needs to be very significant advances in the amount of target compounds produced in the bioreactor plants and to develop other plant species as bioreactors. The aim of this project is to develop technologie ....Extreme expression: building a platform for industrial plant biotechnology. Plants have remarkable potential as bioreactors for the production of usually non-plant compounds such as medical proteins, industrial proteins including enzymes and polymers. However, to realise this potential, there needs to be very significant advances in the amount of target compounds produced in the bioreactor plants and to develop other plant species as bioreactors. The aim of this project is to develop technologies that provide the platform to produce large quantities of target novel compounds in plants and extend the range of plant species that can be used as bioreactors. These technologies will provide the basis of a dynamic biofarming industry in Australia.Read moreRead less
Pelagic ecosystem linkages in a changing Southern Ocean. Our study, which aims to better describe and understand the ecology of the vast Ocean to the south of Australia, will provide the information that will assist in managing this region in an era of change. Many species are of significant conservation concern, others are recovering from previous harvesting, some are being harvested and all will be affected by a changing climate. Understanding the ecosystem linkages and the way in which the p ....Pelagic ecosystem linkages in a changing Southern Ocean. Our study, which aims to better describe and understand the ecology of the vast Ocean to the south of Australia, will provide the information that will assist in managing this region in an era of change. Many species are of significant conservation concern, others are recovering from previous harvesting, some are being harvested and all will be affected by a changing climate. Understanding the ecosystem linkages and the way in which the physical environment affects the distribution and abundance of key ecosystem components will allow us to better manage the system and to predict the effects of future climate change. Read moreRead less