Childhood Retinal Characteristics: Optical Coherence Tomography And Clinical Comparisons
Funder
National Health and Medical Research Council
Funding Amount
$64,631.00
Summary
Optical Coherence Tomography (OCT) of the optic disc and retina has been introduced rapidly into clinical practice, yet there is a paucity of data on its normal distribution or its comparisons with clinical appearances as seen in photographic images. Using the extensive database of OCT and optic disc photos of a population sample of 4091 schoolchildren, influences of confounders (eye size and shape, body size, refraction) will be assessed to aid clinicians in their interpretation of OCT results.
Inferring Global Regulatory Architecture Of Human Gene Expression In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$47,427.00
Summary
Our genome encodes ~25,000 genes that shape out an individual from head to toe. Malfunction of a particular gene could cause fatal health problem or disease. Nonetheless, the mis-regulation of functioning genes can also result in serious diseases. In this study, we are going to use large-scale gene regulation information and advanced computing techniques to clarify the regulation network of human genome on a global level. Hence, helping us to understand more about diseases of gene transcription.
Identifying Molecular Signatures Of Type 1 Diabetes.
Funder
National Health and Medical Research Council
Funding Amount
$49,442.00
Summary
Type 1 diabetes is caused by loss of the insulin-producing beta cells of the pancreas. Certain white blood cells of the immune system direct a damaging inflammatory response towards beta cells. Patients become ill once most of the beta cells are destroyed. This project aims to identify molecular signatures within subjects' blood which reflect the destruction. These markers will help predict diabetes risk, assess severity and response to treatment, as well as define targets for intervention.
A Comparison Of Loaded And Unloaded Exercise For People With Non-specific Chronic Low Back Pain (NSCLBP)
Funder
National Health and Medical Research Council
Funding Amount
$42,410.00
Summary
Chronic low back pain is a common and costly condition. This research will conduct studies to determine the important ingredients of exercise programs that are related to successful outcomes for people with chronic low back pain (CLBP) and also to determine the effects of an exercise program intended to strengthen or load the low back muscles and a program that encourages movement restoration through movement not intended to strengthen for people with non-specific CLBP.