Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast ....Synchrotrons, wavelet analysis and novel imaging techniques - applying physics tools to the war against breast cancer. Breast cancer leads to the second highest number of person-years of life lost due to cancer in Australia, with little known about its transport around the body. Current screening methods for breast cancer are neither 100% sensitive or specific and are heavily dependent upon expert training. This project will contribute by yielding valuable information on the transport of breast cancer and contribute to the development of an automated diagnostic method, with the possibility of its application to other diseases. The project will also involve members of the regional community, train regional scientists and provide synchrotron experience for Australian scientists in time for Australia's first synchrotron.Read moreRead less
Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important v ....Bayesian inference for complex regression models using mixtures. The project will use mixtures to flexibly model complex regression functions and will develop Bayesian methods for carrying out statistical inference on these models. The models will deal with both Gaussian and non-Gaussian data. Multiple explanatory variables are dealt with by mixing simple additives to produce flexible high dimensional function estimates. Variable selection and model averaging will be used to identify important variables and thus make the estimation more efficient. The methods will be extended to multivariate responses where account will taken be taken of the structure of the dependence between responses.Read moreRead less
Nonlinear Dynamics of Pulse Coupled Oscillators. A mathematical model of the heart pacemaker system will be created, based on simple interacting units. These units have been shown to be good models of physiological information e.g. the discrimination of different influences on heart rate. We will firstly look at the interaction of the units in simple combinations and then tune the model to mimic the behaviour of the cardiac pacemaker.
Potential benefits may arise from elucidating the mechanis ....Nonlinear Dynamics of Pulse Coupled Oscillators. A mathematical model of the heart pacemaker system will be created, based on simple interacting units. These units have been shown to be good models of physiological information e.g. the discrimination of different influences on heart rate. We will firstly look at the interaction of the units in simple combinations and then tune the model to mimic the behaviour of the cardiac pacemaker.
Potential benefits may arise from elucidating the mechanisms underlying arrhythmias which contribute to ?sudden cardiac death? in young men, and suggesting strategies for artificial pacemakers to effectively arrest abnormal rhythms before they convert to potentially fatal fibrillation.Read moreRead less
Model Update with Localisation, Constraints and Abstraction. This project will fundamentally provide a new paradigm and a system prototype for advanced computer aided system modification. It will significantly enhance Australia's leading role in the cutting edge research in computer aided system development. By applying the new methodology and technology, Australian IT industry will significantly improve its capacity for developing highly complex hardware and software systems for various applica ....Model Update with Localisation, Constraints and Abstraction. This project will fundamentally provide a new paradigm and a system prototype for advanced computer aided system modification. It will significantly enhance Australia's leading role in the cutting edge research in computer aided system development. By applying the new methodology and technology, Australian IT industry will significantly improve its capacity for developing highly complex hardware and software systems for various applications. With a strong research program across different areas such as knowledge system update, model checking and software development, and a collaborative research training environment, this project will strengthen Australia's international reputation as a leader in computing and IT research.Read moreRead less
Developing Sophisticated e-Business Automation. This project will provide theoretical foundations and a practical platform for developing advanced e-business automation technology. As such, it will significantly enhance Australia's leading role in the cutting edge research on e-business automation. By applying the new methodology and technology, Australian IT industries will be able to develop highly efficient e-market application systems, which will be financially beneficial to most organizatio ....Developing Sophisticated e-Business Automation. This project will provide theoretical foundations and a practical platform for developing advanced e-business automation technology. As such, it will significantly enhance Australia's leading role in the cutting edge research on e-business automation. By applying the new methodology and technology, Australian IT industries will be able to develop highly efficient e-market application systems, which will be financially beneficial to most organizations as Australia business and institutions are moving towards a more electronically oriented future. With a strong research team and collaborative research training environment, this project will further promote Australia's international reputation as a leader in Computing and IT research.Read moreRead less