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Research Topic : Obsessive-Compulsive Disorder
Field of Research : Mental Health
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  • Funded Activity

    Preconception Predictors Of Health, Behaviour And Emotional Adjustment At Seven Years

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,170,830.00
    Summary
    An understanding of the importance of a healthy start to life has underpinned major health policies including Australia’s National Agenda for Early Childhood. The capacity of parents to provide that healthy start has received little study. The present project investigates the extent to which parental lifestyle, social and emotional adjustment prior to conception predictor emotional problems, disruptive behaviour and health in their children at seven years.
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    Funded Activity

    Integrating Treatment For Alcohol Use Problems And Comorbid PTSD

    Funder
    National Health and Medical Research Council
    Funding Amount
    $658,073.00
    Summary
    Comorbid alcohol use problems and posttraumatic stress disorder (PTSD) are common mental health problems that cause disability and distress. Despite this, there are few randomized controlled trials of interventions. The proposed study is the first Australian randomised controlled trial in this field to address the question of whether treating PTSD and alcohol use problems is superior to treating alcohol use problems alone. The study compares the relative efficacy of a manual guided treatment for .... Comorbid alcohol use problems and posttraumatic stress disorder (PTSD) are common mental health problems that cause disability and distress. Despite this, there are few randomized controlled trials of interventions. The proposed study is the first Australian randomised controlled trial in this field to address the question of whether treating PTSD and alcohol use problems is superior to treating alcohol use problems alone. The study compares the relative efficacy of a manual guided treatment for alcohol use disorder alone with a simultaneous treatment for alcohol use and PTSD. This study improves on the methodological limitations described in the two existing studies reported in the published literature. Two-hundred and sixty four participants will be recruited from mutiple sites (media, GPs, specialist clinics) and treated in the community at two sites in Sydney. Participants will be eligible if they consume harmful levels of alcohol (NHMRC risky or high risk levels) and have a concurrent diagnosis of PTSD based on recognised diagnostic criteria. Treatment will consist of 16 sessions of manual guided individual psychological therapy that has been found to be very efficacious with each problem alone. The efficacy of treatment will be determined on the basis of reductions in harmful drinking (above NHMRC low risk levels) and in symptoms of PTSD. Participants will be followed up by an independent, blind, clinician three and six months after treatment completion. The findings of this study have the potential to provide valuable information regarding the treatment needs of people with these complex presentations to clinicians and policy developers alike.
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    Funded Activity

    Panic Disorder: Neurobiology And Mechanisms Of Cardiac Risk

    Funder
    National Health and Medical Research Council
    Funding Amount
    $456,657.00
    Summary
    Some people are subject to episodes of recurring, often inexplicable anxiety which are very unpleasant and accompanied by physical symptoms such as sweating, palpitations, tremor and a sensation of suffocation. Recurring attacks over a period of months, or years, forms the basis for the diagnostic of panic disorder. It has until recently been felt that although panic disorder was distressing and disabling, it did not constitute a risk of life. Sufferers often fear that they have heart disease, b .... Some people are subject to episodes of recurring, often inexplicable anxiety which are very unpleasant and accompanied by physical symptoms such as sweating, palpitations, tremor and a sensation of suffocation. Recurring attacks over a period of months, or years, forms the basis for the diagnostic of panic disorder. It has until recently been felt that although panic disorder was distressing and disabling, it did not constitute a risk of life. Sufferers often fear that they have heart disease, because of the nature of their symptoms, but have been reassured that this is not the case. Recent epidemiological studies, however, indicate that there is an increased risk in patients with panic disorder. Our hypotheses in this research project are as follow: That some specific genes predispose to the development of panic disorder - through actions on the nervous system and blood vessels That drug treatment (selective serotonin uptake blockers) and psychological treatment (cognitive behaviour therapy, CBT) reduce cardiac risk in panic disorder We will test these hypothesis using state of the art clinical scientific methods. Panic disorder has an important cardiological dimension which needs to be better understood for cardiac protection to be achieved in panic disorder patients.
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    Funded Activity

    Impact Of A Sleep Intervention In Children With ADHD: A Randomised Controlled Trial

    Funder
    National Health and Medical Research Council
    Funding Amount
    $384,230.00
    Summary
    Attention deficit hyperactivity disorder (ADHD) affects up to 7.5% of Australian children. Between 50 and 70% of parents also report sleep problems (eg night waking, insomnia) in their child with ADHD. Such sleep problems are associated with poorer child behaviour, concentration, and school attendance as well as poorer parent mental health and work attendance. This randomised controlled trial will determine whether treating sleep problems in children with ADHD can improve these outcomes.
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    Funded Activity

    The Pubertal Onset Of Mental Disorders And Early Substance Abuse

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,118,072.00
    Summary
    Mental disorders and early substance abuse are the most important health problems affecting adolescents and young adults in Australia, yet we have no preventive interventions for mental disorders with strong and sustained effects. Around one half of all mental disorders begin at puberty. This proposal outlines plans for the first study to comprehensively study the onset of mental disorder at this time. It will lay a foundation for the next generation of prevention studies.
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    Funded Activity

    Building The Evidence Base For Prevention And Recovery Care Services

    Funder
    National Health and Medical Research Council
    Funding Amount
    $365,903.00
    Summary
    This project involves seven inter-related studies designed to evaluate the appropriateness, effectiveness and efficiency of Victoria's Prevention and Recovery Care Services (PARCS), which are residential services for people with severe mental disorders. The project represents a partnership between universities, PARCS providers, clinical services and the Victorian Government, and will actively engage service users and their carers and other experts
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    Funded Activity

    Predictors Of Response To Antidepressants: Evidence From Clinical, Psychometric, Neurogenetic And Neuroimaging Measures.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $274,312.00
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    Funded Activity

    Epidemiology, Classification And Treatment Of Comorbid Substance Use And Post Traumatic Stres Disorder

    Funder
    National Health and Medical Research Council
    Funding Amount
    $394,460.00
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    Funded Activity

    Australian Longitudinal Study Of Heroin Dependence: An 18-20yr Prospective Cohort Study Of Mortality, Abstinence, And Psychiatric And Physical Health Comorbidity

    Funder
    National Health and Medical Research Council
    Funding Amount
    $1,210,319.00
    Summary
    The burden associated with heroin dependence is undeniable. But little is known about the natural history and long-term course of heroin dependence; knowledge that is critical for informing the development of new treatment interventions, health care planning and service delivery. We propose to extend our study of 615 Australians with heroin dependence, recruited in 2001-2002, to 18-20 years follow-up to answer critical questions about the long-term impact of this condition.
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    Funded Activity

    An Internet Based Intervention For The Prevention And Treatment Of Posttraumatic Stress Disorder.

    Funder
    National Health and Medical Research Council
    Funding Amount
    $96,790.00
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    Showing 1-10 of 32 Funded Activites

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