Improving The Measurement Of Non-fatal Injury Burden - Validating The Global Burden Of Disease (GBD) Project Through Synthesis And Analysis Of The Six Leading Injury Outcome Cohort Studies From Around The World
Funder
National Health and Medical Research Council
Funding Amount
$155,443.00
Summary
This project will use data from the six largest and most comprehensive cohort studies across five countries to evaluate methods for determining the disability associated with injury. The findings will direct how injury burden is measured for by the Global Burden of Disease (GBD) Study, and for individual country or region-specific studies. The research will have direct relevance to Australia by improving outcome measurement in ways that are critical for enhanced clinical, public health policy an ....This project will use data from the six largest and most comprehensive cohort studies across five countries to evaluate methods for determining the disability associated with injury. The findings will direct how injury burden is measured for by the Global Burden of Disease (GBD) Study, and for individual country or region-specific studies. The research will have direct relevance to Australia by improving outcome measurement in ways that are critical for enhanced clinical, public health policy and planning settings.Read moreRead less
Long-term Outcome After Stroke: Survival, Stroke Recurrence, Functional Ability And Costs.
Funder
National Health and Medical Research Council
Funding Amount
$649,971.00
Summary
Stroke is the third most common cause of death in Australia, and is more common in the older age groups. Because the population most at risk of developing stroke is growing faster than the rest of the population, it is likely that there will be a large increase in the number of strokes occurring in coming years. At 1 year after stroke about one-third of patients have died, a third remain severely disabled and a third recover with minimal disability. In Australia, there is no information on outco ....Stroke is the third most common cause of death in Australia, and is more common in the older age groups. Because the population most at risk of developing stroke is growing faster than the rest of the population, it is likely that there will be a large increase in the number of strokes occurring in coming years. At 1 year after stroke about one-third of patients have died, a third remain severely disabled and a third recover with minimal disability. In Australia, there is no information on outcome beyond 5 years. It is thought that at 10 years after stroke about 70% of patients will have died, and a further 5-10% will have had another nonfatal stroke. The aim of this study is to assess the long-term outcome of patients with stroke. These will include measures of survival, stroke recurrence, and ability to perform usual daily activities. The use of health care and community resources and the associated costs of this will also be assessed. Information on survival patterns, stroke recurrence, disability and costs will be of great value for health service planning. Such information will also be useful to patients, their families, and medical staff who treat these patients.Read moreRead less
Investigating The Association Between Incarceration While Pregnant And Maternal And Infant Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$307,500.00
Summary
The number of women incarcerated within Australian prisons has doubled over the last ten years. Prisons contain large numbers of women from Indigenous backgrounds, women with a mental illness, women with violent partners and women with substance abuse problems. As such they constitute one of the most disadvantaged groups within Australian society and their children are unlikely to experience a healthy start to life. At any one time around 5-10% of women inside Australian prisons are pregnant. Th ....The number of women incarcerated within Australian prisons has doubled over the last ten years. Prisons contain large numbers of women from Indigenous backgrounds, women with a mental illness, women with violent partners and women with substance abuse problems. As such they constitute one of the most disadvantaged groups within Australian society and their children are unlikely to experience a healthy start to life. At any one time around 5-10% of women inside Australian prisons are pregnant. There has been no Australian research into the effect incarceration has upon pregnant women or their babies. Some believe that women who are incarcerated during their pregnancy may have better outcomes as they are outside their normal milieu with restricted access to alcohol and illicit drugs and separated from abusive partners. Others argue that the stress of incarceration and separation from family and friends could result in poorer pregnancy outcomes. This study will investigate whether being imprisoned while pregnant results in better or worse pregnancy and birth outcomes for Australian women and their babies.Read moreRead less
Fundamental flaws in the design and reporting of research outcomes can undermine evidence-based medicine, impede patient-centred care, cause harm to patients, and result in a waste of research dollars. Our 3-year multinational project engages with patients, caregivers, clinicians, researchers and policy makers, to establish core outcomes in haemodialysis. This will ensure that patient-centred outcomes are consistently measured and reported in haemodialysis trials and other forms of research.
Informing Vaccination Strategies For Pregnant Women Through Linked Population Health Data
Funder
National Health and Medical Research Council
Funding Amount
$318,768.00
Summary
Vaccination during pregnancy has health benefits for mothers and their infants; however, it is a relatively new area of research, and the immediate and long-term consequences for children are currently not well understood. As part of this fellowship, I plan to conduct research into the long-term health impacts of vaccination during pregnancy. This fellowship will build my career as a perinatal epidemiologist and establish expertise in Australia related to vaccines given during pregnancy.
Identifying And Implementing Standardised Outcomes In Kidney Transplantation
Funder
National Health and Medical Research Council
Funding Amount
$274,076.00
Summary
The inconsistencies and lack of patient involvement in outcome selection for research can undermine shared decision-making and patient-centred care. Over three years, this global project will bring together patients,family members, healthcare providers, policy makers and industry to identify core outcomes in kidney transplantation. Implementation of the core outcome set will ensure that outcomes report in research are relevant, meaningful and important to patients with a kidney transplant.
Determinants Of Child Health And Development: Populations, Partnerships, Pathways And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$8,214,333.00
Summary
There are considerable challenges to the study of complex health and developmental problems in children and young people. Despite increasing prosperity in Australia, many of these problems are not abating and some appear to be increasing. These include low birthweight, behavioural and mental health problems, autism, obesity and, in Indigenous children, infections. This Program proposes investigating these problems with a view to prevention, thus meeting the national research priority of Promotin ....There are considerable challenges to the study of complex health and developmental problems in children and young people. Despite increasing prosperity in Australia, many of these problems are not abating and some appear to be increasing. These include low birthweight, behavioural and mental health problems, autism, obesity and, in Indigenous children, infections. This Program proposes investigating these problems with a view to prevention, thus meeting the national research priority of Promoting and Maintaining Good Health, particularly _a healthy start to life� and _preventive health care�. The Program is unique in that it brings together a multi-disciplinary team of researchers of international repute to investigate these complex issues. The research team comprises epidemiologists, clinicians, developmental psychologists, biostatisticians, sociologists and other social scientists. This team has a proven track record in producing research outcomes that have translated into innovative health policy and practice in areas as diverse as: - the use of folic acid in spina bifida prevention - understanding cerebral palsies - suicide prevention and mental health in children and young people - Aboriginal child health and development - intellectual disabilities including Rett syndrome and autism - in vitro fertilisation and birth defects. The factors influencing how children develop into young adults include genetic inheritance, nutrition and growth, and family, socioeconomic and environmental conditions. This work demands new ways of measuring and analysing these factors in populations of children and their families. Western Australia is one of only three sites in the world to have comprehensive linked health data on the whole of its population of children and their families. This Program comprises five overlapping themes of research planned around these unique population databases. The five themes are: - social, economic and psychological influences on child health and development - many paths to poor health are linked to social disadvantage. Examining these issues may explain why some childhood conditions are worsening or not improving - pathways to wellbeing, resilience and developmental disorders, including intellectual disability, autism, birth defects and cerebral palsy - nutrition and growth, particularly as it relates to low birthweight, childhood obesity and mental health - infectious disease, its causes and its influence on lifelong health problems and disabilities - Aboriginal health _ whilst spanning each of the research themes above, it presents its own unique challenges and requires it�s own unique solutions. This Program will investigate how children develop into young adults and will examine the influence of their families, nutrition and growth and socioeconomic and environmental conditions. It will develop new ways of measuring and analysRead moreRead less
Improving The Identification, Management And Outcome Of People With Depression And Other Chronic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
My research is designed to reduce depression and help people with chronic disease have a better quality of life. I will work with Aboriginal and/or Torres Strait Islander communities to improve how depression is identified, prevented and treated. I will work with the general community who have major depression, depression that is difficult to treat and people with depression and chronic disease to improve their outcomes. I will also aim to improve the recovery of people who have had a stroke.