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Uptake of fertility preservation procedures (eg. egg and embryo freezing) prior to cancer treatment is increasing and women will return to use these to try to conceive. Radiation may damage the uterus and there is insufficient evidence to guide the management of those exposed to intermediate doses. The aim is to improve understanding of radiation effects on the uterus which will assist clinicians with deciding whether it can support a pregnancy, or if surrogacy should be advised.
The aim of this project is to determine whether melatonin supplementation has an effect on cumulative pregnancy and delivery rates, allowing for the use of frozen embryos obtained during a melatonin treatment cycle. This will be achieved by a series of experiments designed to investigate the effect of melatonin on follicular fluid and culture media as well as assessing clinical pregnancy rates and delivery rates.
Three percent of children born in Australia are from IVF. It is typical in IVF to replace 2 or more embryos in order to attain an acceptable pregnancy rate. However, twin pregnancies are common as a result, with 25% of all twins coming from IVF. Twins represent a real medical issue for mother and infants. Therefore, this research will use new highly innovative technologies to determine the health of an individual embryo in the culture dish prior to transfer, making the selection and transfer of ....Three percent of children born in Australia are from IVF. It is typical in IVF to replace 2 or more embryos in order to attain an acceptable pregnancy rate. However, twin pregnancies are common as a result, with 25% of all twins coming from IVF. Twins represent a real medical issue for mother and infants. Therefore, this research will use new highly innovative technologies to determine the health of an individual embryo in the culture dish prior to transfer, making the selection and transfer of an individual embryo a reality.Read moreRead less