Premature Mortality Post Fracture:A NSW Linked Data Study
Funder
National Health and Medical Research Council
Funding Amount
$391,012.00
Summary
Osteoporotic fractures are associated with increased morbidity and mortality. Anti-osteoporosis medications reduce re-fracture and possibly morality, yet osteoporosis is poorly treated. This study will link information from >260,000 people (45&Up study) with hospital admissions, medications and deaths to create the largest, detailed dataset of its kind. We will be able to determine cause of any fracture-associated mortality and the effect of medication to improve osteoporosis management.
Health Consequences For Mother And Baby Of Substantial Pre-conception Weight Loss In Obese Women
Funder
National Health and Medical Research Council
Funding Amount
$93,418.00
Summary
Obesity (BMI >30kg/m2) is now very common in women of child-bearing age.There is strong evidence that maternal obesity increases the rate of pregnancy complications, and affects the growth and well-being of the fetus in-utero. This project aims to determine how substantial pre-conception weight loss, achieved using a Very Low Energy Diet (VLED), impacts maternal and neonatal health outcomes.
The Management Of Women With Type 1 Diabetes During Pregnancy And Breastfeeding.
Funder
National Health and Medical Research Council
Funding Amount
$50,741.00
Summary
Pregnancy in women with type 1 diabetes is associated with increased risks to the mother and baby and lower rates of breastfeeding. There is a relative paucity of published studies concerning the management of these women particularly in late pregnancy, immediately after delivery and during breastfeeding. Through a series of studies this project aims to address these areas of uncertainty and thereby improve the management of these women during these periods.
The Treatment Of BOoking Gestational Diabetes Mellitus Study: The TOBOGM Study
Funder
National Health and Medical Research Council
Funding Amount
$2,197,280.00
Summary
Gestational diabetes mellitus (GDM) related pregnancy complications are reduced with treatment from 24-28 weeks pregnant. Many women are diagnosed/treated earlier without evidence of benefit and possible risk of harm. In TOBOGM women under 20 weeks pregnant with mildly raised blood glucose will be allocated by chance to either immediate treatment, or awaiting a repeat diabetes test at 24-28 weeks pregnant to decide treatment. Harmful and beneficial effects on mother and baby will be compared.
Birth Outcomes And Body Composition In Babies Born To Mothers With Diabetes In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$109,358.00
Summary
This study will evaluate outcomes and body composition in neonates born to mothers who have diabetes during their pregnancy in the Northern Territory. Babies born to mothers with diabetes may be at higher risk of complications during birth and later in life may have increased risk of obesity and diabetes, conditions which are particularly prevalent in the Indigenous population and contribute to high morbidity and mortality rates. This study will be important to evaluate these factors, particular ....This study will evaluate outcomes and body composition in neonates born to mothers who have diabetes during their pregnancy in the Northern Territory. Babies born to mothers with diabetes may be at higher risk of complications during birth and later in life may have increased risk of obesity and diabetes, conditions which are particularly prevalent in the Indigenous population and contribute to high morbidity and mortality rates. This study will be important to evaluate these factors, particularly in a high risk population.Read moreRead less