Oral Health Research For The Australian Population
Funder
National Health and Medical Research Council
Funding Amount
$2,501,265.00
Summary
This program will build capacity and expertise in Australia s population health research workforce. The program will pursue the broad research theme adding value to oral health surveys . Over a period of five years, eight junior researchers will work on projects that enhance the value of six oral health surveys within the Australian Research Centre for Population Oral Health at The University of Adelaide. Projects will range from analysis of inflammation caused by periodontal (gum) disease in th ....This program will build capacity and expertise in Australia s population health research workforce. The program will pursue the broad research theme adding value to oral health surveys . Over a period of five years, eight junior researchers will work on projects that enhance the value of six oral health surveys within the Australian Research Centre for Population Oral Health at The University of Adelaide. Projects will range from analysis of inflammation caused by periodontal (gum) disease in the Australian population, to evaluation of school dental services provided over the last 30 years. Team investigators will work on these surveys to tackle public health problems confronting four distinct dental generations of Australians: _1) people in the oldest tooth loss generation who have lost, on average, half of their natural teeth; 2) the amalgam generation of middle-aged adults who had unprecedented numbers of cavities that are now filled - treatment that requires extensive maintenance and repair; 3) the younger fluoride generation that has historically-low rates of dental decay; 4) and today s pre-schoolers among whom there is disturbing evidence that oral disease is becoming concentrated within the most disadvantaged segments of the population. Their work will improve the information base needed to promote oral health and prevent oral illness in the Australian population.Read moreRead less
The Australian Health Inequalities Research Program (AHIRP)
Funder
National Health and Medical Research Council
Funding Amount
$601,484.00
Summary
This research proposal focuses on the monitoring and surveillance of health inequalities in Australia, the measurement and collection of socioeconomic data, improving our knowledge and understanding of health inequalities, investigating policies and interventions to reduce health inequalities, and strengthening Australia’s research capacity and infrastructure as these relate to health inequalities.
Study Of The Relationship Of Oral Health And Oral Health Service Utilisation To The General Health Of Older Australian Men
Funder
National Health and Medical Research Council
Funding Amount
$471,564.00
Summary
The mouths of older Australians now are very different to those of previous generations. The prevalence of complete tooth loss is declining rapidly and this has enormous implications for dental services. This study will use the established Concord Health and Ageing in Men Project (CHAMP) as a platform to conduct a study of oral health and oral health service use in 800 older men. A major focus of the study will be the inter-relationships between oral health and physical and mental health.
Allostatic Mediators Of Socioeconomic Inequalities In Periodontitis Among Australian Adults
Funder
National Health and Medical Research Council
Funding Amount
$368,000.00
Summary
Periodontal (gum) disease is a significant cause of tooth loss among adults in Australia. Bacteria (germs) that stick to teeth in dental plaque are the primary cause of gum disease. However, the amount of damage caused to the gums depends heavily on the body's immune system which fights infection throughout the body. Like many other health conditions, gum disease occurs at a higher rate in people in a relatively low socioeconomic-position (SEP) compared to people from high SEP. Studies of other ....Periodontal (gum) disease is a significant cause of tooth loss among adults in Australia. Bacteria (germs) that stick to teeth in dental plaque are the primary cause of gum disease. However, the amount of damage caused to the gums depends heavily on the body's immune system which fights infection throughout the body. Like many other health conditions, gum disease occurs at a higher rate in people in a relatively low socioeconomic-position (SEP) compared to people from high SEP. Studies of other health conditions have shown that psychosocial stress (eg. job strain, financial stress) disproportionately affects people in low SEP groups. Stress, in turn, is known to alter the body's defense mechanisms, including the immune system, contributing to higher rates of conditions such as heart disease. Researchers have used the term allostatic load to describe this failure of the body's defense system under stress. Stress has also been suggested as a contributing factor in gum disease. This study will investigate whether this sequence of events producing allostatic load also plays a role in gum disease. We will study a random sample of 610 Australian adults from the full range of SEP backgrounds. We will ask them about their experience of daily stress, and measure their levels of gum disease and dental plaque. We will also collect samples of fluid from around their gums to measure quantities of two chemicals that indicate the activity of immune defense mechanisms in the gums. We will analyze these results to determine whether stress affects the body's responses to dental plaque, and whether that response accounts for differences in levels of gum disease between SEP groups. Results from this study will pinpoint the role of common bodily defense mechanisms in the development of gum disease. These results may help to identify sources of stress that, if controlled, could reduce rates of gum disease and other conditions affected by allostatic load.Read moreRead less
Integration Of Epidemiological, Biological, And Health Services Data In Cancer Research
Funder
National Health and Medical Research Council
Funding Amount
$290,032.00
Summary
Improved understanding of carcinogenic mechanisms, such as the importance of gene and environment interaction, has placed increased emphasis on the need for studies combining biological and epidemiological data. The proposed research program incorporates a number of cross-disciplinary studies which bridge classical epidemiology and basic science and strive to improve the clinical relevance and translational potential of research outcomes.
Improving Cancer Outcomes In Under-studied Cancers By Understanding Their Risk Factors And Patterns Of Cancer Care.
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
Cancer is the second leading cause of disease burden in Australia. Much can be done to reduce this burden through effective cancer prevention and ensuring all patients receive optimal evidence-based care. This research focuses on thyroid, kidney and ovarian cancer and aims to increase knowledge of these cancers’ causes and to investigate variation in patient care and its impact on outcomes. Ultimately the objective of the work is to decrease Australia’s cancer burden.
Generating The Evidence To Control Cancer And Optimise Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$6,564,341.00
Summary
Our Program addresses the public health aspects of common cancers, particularly cancers of the skin and gynaecological tracts. Each year in Australia, nearly 400,000 people are treated for skin cancer, and more than 3,500 women develop ovarian or uterine cancer. Our aims are first, to understand how we might prevent these cancers in the future; second, to enhance diagnosis of these cancers; and third, to improve the survival and quality of life for people who are diagnosed with these cancers