Disentangling The Interrelationship Between Multimordibity, Multimedicine Use, And Cardiovascular Health
Funder
National Health and Medical Research Council
Funding Amount
$480,978.00
Summary
Australians are living longer, but are also living with more health conditions and taking more medicines to treat those conditions. For people with cardiovascular disease (CVD), this is a problem as hundreds of non-cardiac medicines known to increase the risk of cardiovascular events, such as myocardial infarction, stroke, or heart failure. We will take a holistic, patient-centred approach determine the true burden of CVD related to use of medicines to treat comorbid conditions in Australia.
Integration And Implementation Of Deprescribing Recommendations To Reduce Medication Induced Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,544,073.00
Summary
Older people in Australia commonly take multiple medicines for their health conditions. As people age and their health changes, medicines that were once helpful may become harmful. This research program will investigate how we can enhance treatment guidelines and use these guidelines in practice to increase discontinuation of unnecessary and potentially harmful medicines. This will lead to reduced medicine induced harm and may improve the quality of life of older Australians.
Understanding Frailty In Older People: An Epidemiological Insight
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
We need to find better and more efficient ways to identify older people at risk of poor outcomes. The measurement of frailty, a key concept in geriatric medicine, may provide this exact information. The proposed research will investigate frailty in large-scale population datasets across both community and hospital settings. Results can be used to guide patient management, influence public health policy and inform future intervention studies.
Implementing Delirium Prevention In Hospitalised Older Patients Using Normalisation Process Theory
Funder
National Health and Medical Research Council
Funding Amount
$175,303.00
Summary
Hospital-acquired delirium in older people is preventable. The study aim is to translate the research evidence for the prevention and management of delirium in hospitalised older people into practice. The outcome will be person and family-centred delirium prevention practices embedded into nursing work, with delirium prevention integrated into the workplace culture of Gold Coast Health. A collaborative implementation model inclusive of end users, namely nurses and consumers, will be used.
Prospective Study Of The Emergence Of Syndromal And Sub Syndromal Anxiety And Depression During Cognitive Decline.
Funder
National Health and Medical Research Council
Funding Amount
$555,696.00
Summary
In older people it is well known that memory impairment and cognitive decline are associated with depression and anxiety. However, it is remains quite uncertain which comes first. For a long time it had been thought that deteriorating brain function associated with ageing and the development of dementia is also the cause of new symptoms of depression and anxiety found in older people. Recently, some evidence has emerged to challenge this hypothesis. So we plan to study this question in detail wi ....In older people it is well known that memory impairment and cognitive decline are associated with depression and anxiety. However, it is remains quite uncertain which comes first. For a long time it had been thought that deteriorating brain function associated with ageing and the development of dementia is also the cause of new symptoms of depression and anxiety found in older people. Recently, some evidence has emerged to challenge this hypothesis. So we plan to study this question in detail with data from an existing longitudinal study of ageing women.Read moreRead less
Optimising Pharmaceutical Care For People With Dementia In Acute Care Settings
Funder
National Health and Medical Research Council
Funding Amount
$719,637.00
Summary
Delivering appropriate acute care services for people with dementia is a major healthcare challenge in Australia. People with dementia do not receive appropriate care in hospitals and are more likely to experience worse clinical outcomes compared to people without dementia. This proposal will establish the first large-scale multi-centre cohort of inpatients with dementia, to systematically investigate the impact of hospitalisation on prescribing, clinical and patient-centred outcomes.
Falls and broken bones are costly health problems among the elderly, even more so when there is a growing older population aged over 65 years. In Australia about 1 million older people have at least one fall each year and about 40-60% will sustain major injuries including broken bones. Therefore there is a need to identify effective ways to reduce falls and improve outcomes of those who break a bone, especially of the hip.
Low-intensity Exercise With Blood Flow Restriction: A Novel Training Strategy To Improve Fitness And Function In Older People
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Age-related declines in muscle mass and cardiovascular fitness have debilitating effects on tasks of daily living for older people. Exercise helps to maintain physical abilities, but many older individuals cannot tolerate the recommended high-intensities of training. This research program will assess an innovative form of exercise to increase muscular and cardiovascular fitness for older people, combining low-intensity walking with wearing inflatable cuffs on the limbs to restrict blood flow.