How do nutrient-regulated changes in mitochondrial protein acetylation and sirtuin activity affect mitochondrial function and insulin action? Lysine acetylation affects the function of many proteins. This project will examine how excess nutrient availability and altered sirtuin activity affects the acetylation state and function of mitochondrial proteins. This information may identify therapeutic targets to treat diseases associated with mitochondrial dysfunction.
Non-intrusive human activity sensing with radio signals. This project aims to develop a theoretical framework for sensing and detecting human activities based on wireless radio signals. The framework advances the state-of-the-art by discovering the fundamental theory, and defining a set of principles to guide practical system design. The framework will be validated and its scientific merit demonstrated through building several applications such as contactless human activity detection and vital s ....Non-intrusive human activity sensing with radio signals. This project aims to develop a theoretical framework for sensing and detecting human activities based on wireless radio signals. The framework advances the state-of-the-art by discovering the fundamental theory, and defining a set of principles to guide practical system design. The framework will be validated and its scientific merit demonstrated through building several applications such as contactless human activity detection and vital signs monitoring. This should benefit existing hospital and clinical patient services and promote home-care and self-care services at nationwide.Read moreRead less
Social perception in late adulthood. Social perception refers broadly to the ability to decode and react appropriately to the social signals sent out by other people, and is a critical predictor of social competency and wellbeing. The aim of this project is to gain a clearer picture of when and why older adults experience social perceptual difficulties, as well as any consequences of these difficulties. A key prediction is that those older adults who have most difficulty with social perception w ....Social perception in late adulthood. Social perception refers broadly to the ability to decode and react appropriately to the social signals sent out by other people, and is a critical predictor of social competency and wellbeing. The aim of this project is to gain a clearer picture of when and why older adults experience social perceptual difficulties, as well as any consequences of these difficulties. A key prediction is that those older adults who have most difficulty with social perception will also have lowest wellbeing. Identifying which older adults are most likely to experience social perceptual difficulties, as well as which aspects of social perception are relatively intact, are expected to help to guide interventions on how to maintain wellbeing in old age.Read moreRead less
Smart Glasses: activity recognition for cognitive aid. The project aims to develop an automatic activity recognition system for cognitive aid of dementia and stroke victims. The ‘Smart Glasses’ system will be based on sensors embedded in glasses and machine learning techniques to automatically detect the activity being performed by a patient, and provide feedback. Sufferers will regain independence and autonomy by improving safety awareness around the home; carers will be provided real-time info ....Smart Glasses: activity recognition for cognitive aid. The project aims to develop an automatic activity recognition system for cognitive aid of dementia and stroke victims. The ‘Smart Glasses’ system will be based on sensors embedded in glasses and machine learning techniques to automatically detect the activity being performed by a patient, and provide feedback. Sufferers will regain independence and autonomy by improving safety awareness around the home; carers will be provided real-time information of patient safety status or adverse events; rehabilitation professionals will be able to use feedback to refine a patient’s program and maximise quality and safety of ambulatory rehabilitation care; and patients will improve rehabilitation outcomes through tailored treatment.Read moreRead less
Improving the diagnostic accuracy of detecting functional decline in older people discharged from hospital emergency departments. There is no accurate early screening tool to detect the loss of ability in older people to live independently. This research evaluates a new screening tool to identify the risk of functional decline. This will assist hospital staff to put appropriate discharge plans in place to mitigate against functional decline.