"Smart Food" - The fulcrum in the energy balance equation. The overall aim of the project is to establish how nutrients best promote an increase in energy expenditure and therefore weight loss. The experiments will be performed in rats using sophisticated technologies to introduce specific combinations of fats, carbohydrates or proteins directly into the stomach and then measure energy expenditure in a specialised type of energy burning rather than energy storing fat called brown adipose tissue. ...."Smart Food" - The fulcrum in the energy balance equation. The overall aim of the project is to establish how nutrients best promote an increase in energy expenditure and therefore weight loss. The experiments will be performed in rats using sophisticated technologies to introduce specific combinations of fats, carbohydrates or proteins directly into the stomach and then measure energy expenditure in a specialised type of energy burning rather than energy storing fat called brown adipose tissue. These experiments will uncover the mechanisms that relate nutrients in the stomach and activation of brown adipose tissue. They will provide a framework on which this project can build a knowledge of smart diets that will allow the effective control of body weight through modulation of energy expenditure. Read moreRead less
Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide t ....Plasticity of gastrointestinal vagal afferents. The aim of this project is to identify how leptin modulates specific subtypes of vagal afferent within the gut and the plasticity of this system under different dietary conditions. This proposed project will substantially increase understanding of the interactions between leptin, known to influence food intake, and vagal afferent satiety signals. It will also increase understanding of how these interactions alter in obesity and ultimately provide targets and/or concepts for the pharmacotherapy of obesity.Read moreRead less
Role of ferroxidases in intestinal iron transport. This project will investigate the mechanism by which the body absorbs the essential nutrient iron from the diet. These studies will enhance our knowledge of an important nutritional pathway and improve our capacity to treat diseases where iron absorption is defective, such as the iron loading disorder haemochromatosis.
Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetra ....Indonesian Democracy: The Politics of Failed Reform and Regime Viability. Despite high hopes following the fall of Indonesia's authoritarian regime, political reform has been limited. The project examines the reasons for slow progress. Among the areas to be studied are constitutional and electoral reform, military reform, judicial reform, decentralisation, preservation of order and economic reform. It will argue that the weakness of the state in carrying out reforms is largely due to the penetration of the state itself by vested interests. Limited reforms have only been implemented when the viability of the regime itself has been at stake. This research is significant for Indonesian politics and political theory.Read moreRead less
China's invisible economic leadership: women in family enterprises. Chinese women are generally regarded as not having been in the leadership of economic reform. In contrast, the Chief Investigator's recent research on the new rich in North China suggests that the wives of new entrepreneurs may play significant, though unacknowledged, leadership roles in enterprise development. In particular, it suggests that women often act as business managers and accountants alongside their husbands, especial ....China's invisible economic leadership: women in family enterprises. Chinese women are generally regarded as not having been in the leadership of economic reform. In contrast, the Chief Investigator's recent research on the new rich in North China suggests that the wives of new entrepreneurs may play significant, though unacknowledged, leadership roles in enterprise development. In particular, it suggests that women often act as business managers and accountants alongside their husbands, especially in family based enterprises first established in the private sector. It is now proposed to test the wider applicability of these findings, and explore the consequences for the development of enterprises, families and local politics.Read moreRead less
Using diagnostic tests in science as formative assessment to enhance teaching and learning. The success and continuation of science programs in upper secondary school and university is dependent on foundational improvements in science education in lower secondary schools. This proposal is designed to address this national concern by fostering talent in science and encouraging more students to study and enjoy science in a meaningful way. Through planned formative assessment, teachers will enable ....Using diagnostic tests in science as formative assessment to enhance teaching and learning. The success and continuation of science programs in upper secondary school and university is dependent on foundational improvements in science education in lower secondary schools. This proposal is designed to address this national concern by fostering talent in science and encouraging more students to study and enjoy science in a meaningful way. Through planned formative assessment, teachers will enable students in Years 8-10 to think about the science concepts and consider alternative explanations rather than memorise basic facts for a test or examination which are then forgotten. Practical benefits are a large range of valid and reliable tests and a range of teaching approaches for diagnosing student learning difficulties.Read moreRead less
The development of predictive brain function in preschool children. This project aims to track developmental changes in brain activity and connectivity in typically developing three-to-six year-old children. The preschool years are a time of huge change in children's cognitive abilities, but little is known of the corresponding changes in brain function. This work will use child-optimised magnetoencephalography to test the hypothesis that early cognitive development is characterised by refinemen ....The development of predictive brain function in preschool children. This project aims to track developmental changes in brain activity and connectivity in typically developing three-to-six year-old children. The preschool years are a time of huge change in children's cognitive abilities, but little is known of the corresponding changes in brain function. This work will use child-optimised magnetoencephalography to test the hypothesis that early cognitive development is characterised by refinement of the brain's innate ability to generate predictions about the sensory environment. The resulting insights could improve understanding of neurodevelopmental disorders such as autism.Read moreRead less
The New Rich and the State in China: The social basis of local power. Australia's relationship with China is important for economic, political and social, reasons. This project will generally assist in contributing to understanding about China's social and political development, and will develop specific expertise in the socio-economic environments of its research localities across five provinces that will be of use to Australian companies seeking access to the China market. It will also add to ....The New Rich and the State in China: The social basis of local power. Australia's relationship with China is important for economic, political and social, reasons. This project will generally assist in contributing to understanding about China's social and political development, and will develop specific expertise in the socio-economic environments of its research localities across five provinces that will be of use to Australian companies seeking access to the China market. It will also add to the development of Australia's standing as a major centre of research on contemporary China. Read moreRead less
Remaking Australian Politics: Electioneering from the 19th Century to the 21st. Critics have lamented the apparent decline of elections as meaningful opportunities for rational deliberation; journalists' election reports increasingly focus on campaign methods; politicians have expressed alarm at how little Australians know about Australia's democratic history. This project, the first long-term study of electioneering in Australia, will address each of these issues. It will provide a scholarly pe ....Remaking Australian Politics: Electioneering from the 19th Century to the 21st. Critics have lamented the apparent decline of elections as meaningful opportunities for rational deliberation; journalists' election reports increasingly focus on campaign methods; politicians have expressed alarm at how little Australians know about Australia's democratic history. This project, the first long-term study of electioneering in Australia, will address each of these issues. It will provide a scholarly perspective on sometimes overstated claims of contemporary decline. It will offer journalists and political professionals' insights into changing campaign practices. And it will produce an accessible account of the significance and history of elections for a new generation of Australians, thereby strengthening democratic life. Read moreRead less
Internal and External Sources of Political Instability in East Timor. This project is of direct relevance to Australia through its bilateral and multilateral provision of police to assist in the maintenance of East Timor's law and order, through its training of and support for the East Timor Border Patrol Unit, and its training and support of the East Timor defence force, Falintil-FDTL. The project also goes to the core of Australia's concerns with regional state maintenance (or conversely, pote ....Internal and External Sources of Political Instability in East Timor. This project is of direct relevance to Australia through its bilateral and multilateral provision of police to assist in the maintenance of East Timor's law and order, through its training of and support for the East Timor Border Patrol Unit, and its training and support of the East Timor defence force, Falintil-FDTL. The project also goes to the core of Australia's concerns with regional state maintenance (or conversely, potential state failure), direct bilateral relations with both East Timor and Indonesia, and the triangular relationship between these three states. Read moreRead less