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Developing Youth-centred Health Promotion Strategies To Prevent And Mitigate The Adverse Health Impacts Of Adolescent Pregnancy In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$702,235.00
Summary
Adolescent pregnancy is a major public health concern in Papua New Guinea, the Asia-Pacific region, and other low and middle income countries, with severe health and socio-economic outcomes for young women. This three-year qualitative study will examine the experiences of early pregnancy among young Papua New Guineans (15-24 years). Project outcomes will include the design of youth health services and community-outreach programs to curb the ongoing harm associated with adolescent pregnancy.
Enhancing Clinical Management Of Paediatric Malaria In Endemic Areas With Transmission Of Multiple Plasmodium Species
Funder
National Health and Medical Research Council
Funding Amount
$867,511.00
Summary
Malaria remains a major problem for children in developing countries especially where different types of the disease are common. This set of complementary studies, based at an established research site in PNG aims to develop new treatment strategies for childhood malaria. A novel method of giving medicine via a spray under the tongue for sick children before arrival at hospital and modified dosing schedules of an old drug used for treating parasites hidden in the liver will be studied.
Field-based Evaluation Of A Novel Magneto-optical Technique To Diagnose Malaria
Funder
National Health and Medical Research Council
Funding Amount
$637,411.00
Summary
Highly sensitive and low-cost and rapid malaria diagnosis is crucial for renewed efforts to eliminate the disease. We have developed a magneto-optic technique that can diagnose the presence of malaria parasites in blood samples within minutes, with a sensitivity approaching that of high-tech molecular methods that are not applicable at point of care. Here we propose to take this method from the laboratory to clinical settings in malaria endemic countries to directly evaluate its performance.
Point-of-care HPV-DNA Testing For Cervical Cancer Screening In High-burden, Low-resource Settings
Funder
National Health and Medical Research Council
Funding Amount
$891,184.00
Summary
We will undertake the first field evaluation of a novel, newly-available, easy to use, and highly accurate point-of-care (POC) test for high-risk human papillomavirus (hrHPV) infection that will allow trained health staff to identify women at increased risk of cervical cancer and to provide same-day cervical cryotherapy for pre-cancer lesions identified on clinical examination.
Understanding The Socio-cultural Dimensions Of Tuberculosis In Papua New Guinea: Knowledge To Optimise Public Health Solutions
Funder
National Health and Medical Research Council
Funding Amount
$727,410.00
Summary
Papua New Guinea has among the highest TB incidence rates in the world, with rates in particular areas considerably higher. This three-year qualitative study will examine the socio-cultural contexts of TB control programs. The project outcome will be better contextualised solutions to improve the effectiveness of TB control programs and therefore the spread of TB and its drug resistant forms.
Development And Valuation Of Cancer-specific Multi-attribute Health States For Use In Economic Evaluation
Funder
National Health and Medical Research Council
Funding Amount
$707,671.00
Summary
Economic evaluation is used by the Australian government in deciding which medical services and pharmaceuticals should be funded. This study will develop quality of life utility measures for use in economic evaluation of cancer interventions in Australia and internationally. This represents a significant methodological contribution to the assessment of quality of life, effectiveness and efficiency in cancer, in one of Australia's national health priority areas.
Mapping Plasmodium Falciparum Population Structure And The Source Of Outbreaks In Papua New Guinea
Funder
National Health and Medical Research Council
Funding Amount
$534,786.00
Summary
Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effec ....Molecular studies to map malaria parasite populations are essential for planning and maintaining malaria control in at risk areas. We will develop molecular tools to map malaria parasite populations in Papua New Guinea at high resolution. We will then investigate whether these tools can be used to pinpoint the source of infections in regions where malaria is normally absent. The project will provide valuable information to help focus malaria control efforts to areas where they will be most effective.Read moreRead less
Phase III Study Of The Impact Of A Physical Activity Program On Disease-free Survival For Early Colon Cancer
Funder
National Health and Medical Research Council
Funding Amount
$2,556,385.00
Summary
There is clear evidence that physical activity can reduce the risk of developing bowel cancer and some evidence suggesting it may decrease the risk of a recurrence of bowel cancer. This study will provide reliable evidence as to whether people who participate in a structured physical activity programme after treatment for stage II or III colorectal cancer can increase their likelihood of being alive without a cancer recurrence at three years, compared to those who have standard follow-up.
The Out-and-About Trial: Improving Quality Of Life By Increasing Outdoor Journeys After Stroke
Funder
National Health and Medical Research Council
Funding Amount
$586,009.00
Summary
Many stroke patients cannot walk well when they leave hospital nor use public transport. Escorted outdoor journeys with a rehabilitation therapist can improve outcomes and quality of life after stroke. Yet not many stroke patients do not receive this type of community rehabilitation. This project aims to evaluate an implementation program to change therapists' practice and increase outdoor journeys after stroke. Benefits include improved quality of life and well being for peope with stroke.