Industrial Transformation Research Hubs - Grant ID: IH150100028
Funder
Australian Research Council
Funding Amount
$3,708,510.00
Summary
ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecu ....ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. ARC Research Hub for Integrated Device for End-user Analysis at Low-levels. This hub aims to improve detection of biological materials by building a portable device for rapid, time-critical detection of low-abundance molecular and cellular analytes. It is expected that the resulting technologies would be used at medical points of care, ordinary workplaces and centres of activity to test for tiny levels of targeted molecules. The initial focus would be early diagnosis of disease and point-of-care drug testing for humans and animals, but the technology platform could be used to sample food and environmental toxins. The hub expects these disruptive technologies will make Australian biotechnology, diagnostics, veterinary, agribusiness and manufacturing firms globally competitive.Read moreRead less
A Randomised Controlled Trial (RCT) Of Azithromycin Versus Doxycycline For The Treatment Of Rectal Chlamydia Infection In Men Who Have Sex With Men.
Funder
National Health and Medical Research Council
Funding Amount
$797,906.00
Summary
Rectal chlamydia is very common among gay men; it can exist for long periods without symptoms leading to ongoing transmission. Azithromycin (1 gram single dose) or 7 days doxycycline (100mg twice daily) are the two recommended treatments globally. But, there is concern about rectal chlamydia treatment with reports of up to 22% failure following azithromycin. We will conduct a randomised trial to compare these treatments for rectal chlamydia and determine which drug works better.
Reconstructing the human colonisation of the Pacific using modern and ancient chicken DNA. We will reconstruct one of the last great human migrations, from Island Southeast Asia across the Pacific to Hawaii and Easter Island, using DNA from the domestic chicken, which was carried on the voyage. Ancient and modern DNA, and archaeological data will be used to reveal the source, route, timing, and whether contact was made with South America
Technological innovation and change in supply chain integration. In examining emerging technology that can transform the performance of Australian industry we address the following priority goals: better understanding the processes that will advance knowledge and facilitate the development of technological innovations; the potential application of Radio Frequency Identification (RFID) technologies across an entire supply chain; and the improved management of information in the storage, distribut ....Technological innovation and change in supply chain integration. In examining emerging technology that can transform the performance of Australian industry we address the following priority goals: better understanding the processes that will advance knowledge and facilitate the development of technological innovations; the potential application of Radio Frequency Identification (RFID) technologies across an entire supply chain; and the improved management of information in the storage, distribution, and delivery of products (smart information use). Improvement in the operational efficiency and performance of the supply chain will increase national wealth while minimising environmental impacts on the environment, for example, through the better utilisation of heavy freight carriers.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0238930
Funder
Australian Research Council
Funding Amount
$350,000.00
Summary
Austlit: The Australian Literature Gateway - Enhancement Stage Two. The Austlit: The Australian Literature Gateway Enhancement Stage Two Project will deliver enhanced functionality for researchers using the integrated resource discovery service developed in 2000 and 2001. In 2002, the Gateway will add new bibliographic, biographical and full text sources to the service, and map rich literary relationships based on this data, supporting the development of new research questions on the place of th ....Austlit: The Australian Literature Gateway - Enhancement Stage Two. The Austlit: The Australian Literature Gateway Enhancement Stage Two Project will deliver enhanced functionality for researchers using the integrated resource discovery service developed in 2000 and 2001. In 2002, the Gateway will add new bibliographic, biographical and full text sources to the service, and map rich literary relationships based on this data, supporting the development of new research questions on the place of the national literature in Australian culture. The Gateway's technical infrastructure will be developed to offer a sophisticated browsing interface, customised services to support specific research, and broader interoperability with other services, including flexible education and portal services.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100088
Funder
Australian Research Council
Funding Amount
$700,000.00
Summary
nano infrared and sub micron Raman spectroscopy and imaging. Nano infrared and sub micron raman spectroscopy and imaging: Near-field Infrared (IR) spectroscopy and imaging systems will be coupled to near-field scanning optical microscopes to provide IR spectroscopy and molecular images at less than 20 nanometre lateral resolution. This is unprecedented resolution for infrared fingerprinting and molecular imaging. For two months a year the spectroscopy system will be coupled to the IR beamline at ....nano infrared and sub micron Raman spectroscopy and imaging. Nano infrared and sub micron raman spectroscopy and imaging: Near-field Infrared (IR) spectroscopy and imaging systems will be coupled to near-field scanning optical microscopes to provide IR spectroscopy and molecular images at less than 20 nanometre lateral resolution. This is unprecedented resolution for infrared fingerprinting and molecular imaging. For two months a year the spectroscopy system will be coupled to the IR beamline at the Australian synchrotron, to provide full IR spectral coverage available to all Australian and New Zealand scientists. A confocal raman spectrometer will be upgraded to the ultraviolet to provide spectra at less than 150 nanometre resolution. These systems will provide a unique Australian resource for nanoscientists, biomedical researchers and materials scientists requiring molecular information on the nanoscale.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346876
Funder
Australian Research Council
Funding Amount
$1,584,000.00
Summary
800 MHz NMR Spectrometer for Molecular Structure-Function Analyses. An 800 MHz high-resolution nuclear magnetic resonance (NMR) spectrometer equipped with a triple-resonance cryoprobe is required to support the research of 5 universities in the NSW/ACT area. The high magnetic field of the spectrometer is necessary for the study of proteins, protein-ligand complexes and other biomolecular systems of molecular weight >30,000. Projects previously inaccessible due to sensitivity, solubility or resol ....800 MHz NMR Spectrometer for Molecular Structure-Function Analyses. An 800 MHz high-resolution nuclear magnetic resonance (NMR) spectrometer equipped with a triple-resonance cryoprobe is required to support the research of 5 universities in the NSW/ACT area. The high magnetic field of the spectrometer is necessary for the study of proteins, protein-ligand complexes and other biomolecular systems of molecular weight >30,000. Projects previously inaccessible due to sensitivity, solubility or resolution problems will become tractable. The increased turn-around times afforded by the high sensitivity of the cryo-enabled spectrometer make it possible to provide access for Australian institutions that would not otherwise have access to comparable equipment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347049
Funder
Australian Research Council
Funding Amount
$403,000.00
Summary
Building Australian Literary Knowledge Infrastructure. The primary goal of AustLit: the Australian Literature Gateway is to facilitate and encourage research in, and teaching of, the nation's creative and critical literature. AustLit's innovative world class resource discovery service utilises best practice techniques in information management and knowledge sharing. In 2003, AustLit will develop new technical services and important new content to meet the defined needs of a wide range of educati ....Building Australian Literary Knowledge Infrastructure. The primary goal of AustLit: the Australian Literature Gateway is to facilitate and encourage research in, and teaching of, the nation's creative and critical literature. AustLit's innovative world class resource discovery service utilises best practice techniques in information management and knowledge sharing. In 2003, AustLit will develop new technical services and important new content to meet the defined needs of a wide range of education and information consumers in the area. AustLit provides the foundation for a subject specific digital library that will retain and expand its usefulness into the future.Read moreRead less
Rejuvenating adult stem cells. This project aims to uncover intimate links between metabolic regulation and longevity in adult stem cells, the source of all cells in the body. Understanding why we age and whether ageing is preventable are research challenges which must be first attacked at a cellular level. This project will try to rejuvenate aged stem cells by interfering with a prospective molecular master switch of aging and also develop an approach to identify and select youthful stem cells. ....Rejuvenating adult stem cells. This project aims to uncover intimate links between metabolic regulation and longevity in adult stem cells, the source of all cells in the body. Understanding why we age and whether ageing is preventable are research challenges which must be first attacked at a cellular level. This project will try to rejuvenate aged stem cells by interfering with a prospective molecular master switch of aging and also develop an approach to identify and select youthful stem cells. The results are expected to be important beyond informing the science of ageing, in the areas of tissue engineering, wound healing, embryology and cancer.Read moreRead less