Amelioration Of The Cognitive Deficits In A Model Of Alzheimers Disease
Funder
National Health and Medical Research Council
Funding Amount
$542,890.00
Summary
The project investigates a brain molecule called p75, and the part it plays inmemory impairment in Alzheimer's Disease (AD). We predict that p75 is a vital link in the disease processes affecting memory.This research has the potential to lead to an effective treatment for AD, by stimulating work on compounds with the ability to blockthe damaging functions of p75.
Genotypes And Phenotypes Of Human Primary Non-congenital Antibody Deficiency
Funder
National Health and Medical Research Council
Funding Amount
$544,692.00
Summary
Antibodies represent a key component of the immune system, and a particularly important in defence against bacterial and viral infections. In some individuals, antibody production fails, rendering them more susceptible to infection. In most cases, the mechanism of antibody failure is unknown. This project seeks to determine the genetic and cellular mechanisms of antibody failure. This could improve diagnosis for immune deficiency, and improve our overall understanding of the immune system.