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Advances In The Understanding Of Autoimmune Encephalitides And Associated Movement Disorders In Children
Funder
National Health and Medical Research Council
Funding Amount
$68,832.00
Summary
Encephalitis in childhood can be devastating with long lasting effects and mortality. This research focuses on children who suffer from encephalitis due to an autoimmune process. In such cases many children present with involuntary abnormal body movements. This project will explore whether differences in the nature of these movements or in electroencephalography or brain imaging with MRI, can help early differentiation of different types of autoimmune encephalitis.
Improving Palliative Care For People After Acute Stroke
Funder
National Health and Medical Research Council
Funding Amount
$96,653.00
Summary
Stroke is a leading cause of death, disability and is a symptom burden worldwide. It impacts patients and their families in various ways, including physical, emotional, social, and spiritual aspects. Stroke outcome is uncertain and decision making complex. To date, there is no integrated concept for palliative care in stroke that addresses the appropriate moment to start palliative care for stroke patients.
Nerve And Muscle Excitability In Inclusion Body Myositis
Funder
National Health and Medical Research Council
Funding Amount
$81,294.00
Summary
Our study will use recently developed neurophysiological techniques to study nerve and muscle excitability in sporadic inclusion body myositis, a poorly understood progressive muscle disease for which no effective treatment is known. We will determine whether the electrical properties of nerve and muscle cell membranes are affected and obtain clues as to where this dysfunction may occur. This may aid development of effective therapies through a better understanding of disease mechanisms.
The Neuro-ophthalmological Manifestations Of Human Mitochondrial Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$100,675.00
Summary
Human mitochondrial diseases often result in neuro-ophthalmological abnormalities. We aim to examine a cohort of patients with mitochondrial disease and document the type and degree of neuro-ophthalmological abnormality. We will provide detail on the retina, optic nerve, oculomotor function, eyelids and visual acuity. We will examine the optic nerve in detail and perform optical coherence tomography and visual evoked potentials on each patient. We will compare results to age-matched controls.