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We propose to establish the Australian Mouse Brain Mapping Consortium which is a national network of facilities allowing Australian researchers to better characterise mouse models of neurological diseases such as Alzheimer's Disease and stroke. Just as accurate maps were key to the voyages of geographic discovery in the 17th and 18th century, improved methods of mapping structural and functional changes in the brain of mouse models of neurological disease will be key to discovery in the neurosci ....We propose to establish the Australian Mouse Brain Mapping Consortium which is a national network of facilities allowing Australian researchers to better characterise mouse models of neurological diseases such as Alzheimer's Disease and stroke. Just as accurate maps were key to the voyages of geographic discovery in the 17th and 18th century, improved methods of mapping structural and functional changes in the brain of mouse models of neurological disease will be key to discovery in the neurosciences in the 21st century . For the Consortium the cartographic tools will be magnetic resonance imaging (MRI), microscopy and sophisticated computational methods of mapping brain structure and function. Participants in the Consortium are internationally recognised leaders in brain imaging based at Monash University, the Howard Florey Institute, the Prince of Wales Medical Research Institute and the Centre for Magnetic Resonance and the Queensland Brain Institute, University of Queensland.Read moreRead less
The Australasian Kidney Trials Network will facilitate well-conducted clinical research and foster collaboration between leading researchers in kidney disease. The Network�s focus will be to answer important questions about prevention and treatment of kidney disease to improve health and quality of life outcomes. The Network will be at the forefront of knowledge creation and address complex economic, technological and social needs relating to the patient care and the translation of research into ....The Australasian Kidney Trials Network will facilitate well-conducted clinical research and foster collaboration between leading researchers in kidney disease. The Network�s focus will be to answer important questions about prevention and treatment of kidney disease to improve health and quality of life outcomes. The Network will be at the forefront of knowledge creation and address complex economic, technological and social needs relating to the patient care and the translation of research into clinical practice.Read moreRead less
One Australian dies of Motor Neuron Disease (MND) every day. MND is likely to be due to a genetic susceptibility to an environmental agent such as a toxin or a virus. Recent advances in gene therapy have emphasised the urgent need to find the gene abnormalities in MND. We propose to set up an Australia-wide DNA Bank for MND to allow researchers to look for genetic abnormalities and environmental influences in this disease.