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Mid-Career Industry Fellowships - Grant ID: IM230100154
Funder
Australian Research Council
Funding Amount
$1,049,904.00
Summary
Fungi Power: Designer Fungal Cell Factories for Advanced Biomanufacturing. This project aims to build an advanced biomanufacturing platform based on filamentous fungi in collaboration with industry. Using synthetic biology, the project expects to engineer superior fungal host strains customisable to the needs of the industry and to address their technological gaps. The expected outcomes include the development of cost-efficient and sustainable fungal-based bioprocesses for the companies to produ ....Fungi Power: Designer Fungal Cell Factories for Advanced Biomanufacturing. This project aims to build an advanced biomanufacturing platform based on filamentous fungi in collaboration with industry. Using synthetic biology, the project expects to engineer superior fungal host strains customisable to the needs of the industry and to address their technological gaps. The expected outcomes include the development of cost-efficient and sustainable fungal-based bioprocesses for the companies to produce products, such as fine chemicals, pharmaceutical actives and food ingredients. The project would provide significant benefits by enabling existing and emerging companies' commercial successes and competitiveness in global markets, creating new jobs and resulting in the growth of the bio-economy in Australia.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100180
Funder
Australian Research Council
Funding Amount
$299,105.00
Summary
Gas chromatography: separating inseparables, identifiying unidentifiables. This project aims to provide researchers with an integrated capability for separation, isolation, and precise structural identification of volatile compounds. It expects to deliver a systematic solution using unprecedented, automated multidimensional gas chromatographic separation, isolating pure compounds for off-line characterisation using appropriate spectroscopic tools, for example nuclear magnetic resonance. This wi ....Gas chromatography: separating inseparables, identifiying unidentifiables. This project aims to provide researchers with an integrated capability for separation, isolation, and precise structural identification of volatile compounds. It expects to deliver a systematic solution using unprecedented, automated multidimensional gas chromatographic separation, isolating pure compounds for off-line characterisation using appropriate spectroscopic tools, for example nuclear magnetic resonance. This will provide significant benefits, such as permitting traceability of (bio)-synthetic pathways, better characterise chemical signalling in plants, accelerate identification of advanced intermediates required for total synthesis of alkaloids, improve detection of metabolites, and determine interactions between small allergens and proteins.Read moreRead less
New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry suppl ....New Lead-Free Brass Solutions for Drinking Water Applications. The aim of this Linkage Project is to provide viable material solutions to address the health problem of Lead-contamination in drinking water arising from Leaded-brass plumbing products and the impact Lead-removal from brass will have on the brass industry. In order to achieve this, this project engages leading multidisciplinary researchers along with Australian and international industry partners from across the brass industry supply and sales network. This project seeks to identify and harness the key material-product attributes required to develop and implement new, lead-free alloy alternatives that meet health-compliance, production and commercial viability, that offer benefits across the industry network and health benefits to society.Read moreRead less
Optimising artificial reef structures for nature-based coastal protection . This project aims to develop a novel framework for predicting how artificial reef structures can be optimally designed to protect coastlines from erosion and flooding. It will develop new theory and models to quantify how waves interact with complex reef structures to reduce wave heights and extreme water levels at the shoreline. Expected outcomes include new practical tools and design guidelines that can be adopted by c ....Optimising artificial reef structures for nature-based coastal protection . This project aims to develop a novel framework for predicting how artificial reef structures can be optimally designed to protect coastlines from erosion and flooding. It will develop new theory and models to quantify how waves interact with complex reef structures to reduce wave heights and extreme water levels at the shoreline. Expected outcomes include new practical tools and design guidelines that can be adopted by coastal engineers and managers to maximise coastal protection by reefs. This will boost Australia’s capacity to protect populations and critical infrastructure from coastal hazards and support Australian industries to lead the international development of innovative nature-based coastal protection strategies.Read moreRead less
The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyami ....The “New” Biochemistry of Polyamines: When Metabolic Pathways Collide. Basic biochemistry and the metabolic regulation of proliferation remain as the fundamental building blocks of knowledge in cell biology that have enabled breakthrough advances in biology and medicine. Polyamines are unique and ubiquitous low-Mr amines that play vital roles in many biological processes, including proliferation, DNA/RNA synthesis, etc. This proposal will mechanistically dissect the "new" biochemistry of polyamines, as we have discovered that polyamines are regulated by iron at 2-major levels, involving >10-key polyamine pathway proteins. This proposal represents first-in-field studies specifically designed to dissect mechanisms involved in this relationship. Our Central Hypothesis is that iron regulates polyamine metabolism.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101759
Funder
Australian Research Council
Funding Amount
$385,720.00
Summary
A novel fundamental approach to enable net shape manufacturing of low-cost high-performance titanium alloys . Oxygen is the bottleneck issue of titanium powder metallurgy, which radically deteriorates the ductility of titanium. This project aims to develop the essential fundamental knowledge and technical solutions to mitigate the detrimental effect of oxygen on the ductility of as-sintered titanium products and enable the net-shape fabrication of low-cost high-performance titanium alloys. This ....A novel fundamental approach to enable net shape manufacturing of low-cost high-performance titanium alloys . Oxygen is the bottleneck issue of titanium powder metallurgy, which radically deteriorates the ductility of titanium. This project aims to develop the essential fundamental knowledge and technical solutions to mitigate the detrimental effect of oxygen on the ductility of as-sintered titanium products and enable the net-shape fabrication of low-cost high-performance titanium alloys. This will be achieved by utilising the inexpensive and unique titanium hydride powder, rather than titanium metal powder, and by developing effective oxygen scavengers. The outcomes will form a robust basis for the creation of a viable titanium hydride powder metallurgy business.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100003
Funder
Australian Research Council
Funding Amount
$280,000.00
Summary
Flexible forming facility for low cost light weight applications. Flexible forming facility for low-cost light-weight applications: This project will establish Australia’s first flexible roll forming facility. The facility will be unique in the world, being specifically designed to roll form the most advanced high strength alloys into complex three-dimensional shapes and investigate their material behaviour under a wide range of loading conditions. This technology represents a step change in com ....Flexible forming facility for low cost light weight applications. Flexible forming facility for low-cost light-weight applications: This project will establish Australia’s first flexible roll forming facility. The facility will be unique in the world, being specifically designed to roll form the most advanced high strength alloys into complex three-dimensional shapes and investigate their material behaviour under a wide range of loading conditions. This technology represents a step change in commercial processing and has the capacity to form materials with high strength and limited ductility. This will lead to the development of new techniques for the manufacture of new advanced materials including advanced high strength steels, composites, nano structured metals and light metal alloys for automotive and aerospace applications.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100165
Funder
Australian Research Council
Funding Amount
$390,000.00
Summary
Thermal and mechanical simulation laboratory for light metals. The creation of a thermal and mechanical simulation laboratory for light metals will provide the critical infrastructure needed for generating new alloys and composites. This will extend Australia's competitive advantage in the design of better alloys for expanding applications in the construction, packaging, automotive and aerospace sectors.