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Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100097
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
Advanced characterisation of materials by nuclear magnetic resonance. Advanced characterisation of materials by nuclear magnetic resonance will support a broad range of research possibilities for development of advanced materials for medical, industrial and environmental applications. Details of molecular structure and mobility will be uncovered which will provide guidance for making improvements to new and existing materials.
Complex nano-systems for highly selective imaging and targeting of cells. The aim of the project is to design multi-functional nanoparticles that can be tracked by multiple bio-imaging techniques, such as magnetic resonance imaging (MRI) and positron emission tomography imaging. The nanoparticles are designed to be targetable to specific cell populations and capable of delivering drugs. The project plans to concentrate the MRI-active gadolinium into nanoparticles to generate enhanced images, and ....Complex nano-systems for highly selective imaging and targeting of cells. The aim of the project is to design multi-functional nanoparticles that can be tracked by multiple bio-imaging techniques, such as magnetic resonance imaging (MRI) and positron emission tomography imaging. The nanoparticles are designed to be targetable to specific cell populations and capable of delivering drugs. The project plans to concentrate the MRI-active gadolinium into nanoparticles to generate enhanced images, and to combine this with other imaging modalities to facilitate tracking and sensitivity. Expected outcomes would enable a new approach to extremely accurate and sensitive imaging of tumours to enable the imaging of much smaller tumours than currently possible. This would allow early therapeutic intervention. The nanoparticles are also designed to deliver a therapeutic payload to specific locations, avoiding systemic delivery of toxic anticancer drugs.Read moreRead less
Nanostructured anticorrosive coating for wave energy conversion module. The project will develop new high performance anticorrosion coatings for metal structures, such as a Waverider- a patented wave energy conversion module. It will deliver a strong intellectual property position in the frontier anti-corrosion technology to Australian Industry and train young scientists in the emerging and multidisciplinary field of research.
Metal-organic frameworks as heterogeneous catalytic systems. Catalysts of industrial chemical processes that are soluble in the reaction mixture are often less stable and harder to separate from the products. This project will tackle these issues by integrating such catalysts into an open framework material that combines the advantages of both soluble and insoluble catalysts - a hybrid catalytic material.
Vesicles stabilised by compressed carbon dioxide as nanoreactors and templates for radical polymerisation. A new environmentally friendly method for synthesis of surfactant vesicles involving stabilisation using low pressure carbon dioxide will be applied to the synthesis of hollow polymeric nanoparticles and polymer of well-defined structure. The resulting polymeric structures will have applications in drug delivery and nano-engineered materials.
Novel green scalable chemical peptide synthesis and enzyme immobilization. The Project aims to address the critical issue of developing green processes for the chemical production of peptides including on an industrial scale. It will use unique, biocompatible solid supports that have been invented by our partner SpheriTech Ltd together with other reagents to allow synthesis to be conducted in water rather than toxic organic solvents. Expected outcomes of the Project include an international part ....Novel green scalable chemical peptide synthesis and enzyme immobilization. The Project aims to address the critical issue of developing green processes for the chemical production of peptides including on an industrial scale. It will use unique, biocompatible solid supports that have been invented by our partner SpheriTech Ltd together with other reagents to allow synthesis to be conducted in water rather than toxic organic solvents. Expected outcomes of the Project include an international partnership in highly efficient environmentally-friendly assembly of peptides and of their analogues by both solid phase synthesis and immobilized enzyme-mediated ligation. The clear benefit will be the first novel, water-based, scalable green synthesis of peptides as biological probes and potential therapeutic agents.Read moreRead less
Luminophores and photochromes: towards molecular componentry. This project aims to enhance current knowledge of luminogenic and photochromic molecules, including self-assembled structures, and materials composed thereof, by constructing a computationally guided compound library. Translation of primary outcomes towards utility in emerging technologies including passive light harvesting from transparent surfaces, bio-sensors and photo-responsive devices will be pursued in collaboration with both a ....Luminophores and photochromes: towards molecular componentry. This project aims to enhance current knowledge of luminogenic and photochromic molecules, including self-assembled structures, and materials composed thereof, by constructing a computationally guided compound library. Translation of primary outcomes towards utility in emerging technologies including passive light harvesting from transparent surfaces, bio-sensors and photo-responsive devices will be pursued in collaboration with both academia and industry. The expected outcomes from this project include the creation of opportunities to explore the manufacture and commercialisation of high-value products with Australian industry. This will provide significant benefits, such as reduction in the carbon footprint of homes, businesses and other applicable structures due to passive power generation, while creating jobs and up-skilling the workforce.Read moreRead less
Precision-built dynamic and functional polymer vesicles. The project aims to create new precision-built polymer vesicles with controlled size, stability, functionality and environmental responsiveness to mimic some of the key dynamic functions of the cell. The project expects to generate new knowledge on the dynamic interplay between the polymer and its bilayer including on-demand activated polymerisations and reactions, logic gates and in situ sensors. Expected outcomes of this project include ....Precision-built dynamic and functional polymer vesicles. The project aims to create new precision-built polymer vesicles with controlled size, stability, functionality and environmental responsiveness to mimic some of the key dynamic functions of the cell. The project expects to generate new knowledge on the dynamic interplay between the polymer and its bilayer including on-demand activated polymerisations and reactions, logic gates and in situ sensors. Expected outcomes of this project include new synthetic polymer techniques and new quantitative insights into the role of compartmentalisation on chemical reactions and polymerisations. This project will provide fundamental knowledge on bio/polymer vesicles with great potential to advance the polymer industry in Australia.Read moreRead less
New silane anti-corrosion coatings for steel surfaces. Steel products are a major export for Australia. Orrcon is one of Australia's largest suppliers of steel pipe and tubing. This study of how to stop steel from corroding will produce new breakthroughs in understanding silane chemistry, which is safer, cheaper and more effective in reducing rust, than what is being used today. This new science will benefit Australia's research into corrosion and help us to be more competitive in the export of ....New silane anti-corrosion coatings for steel surfaces. Steel products are a major export for Australia. Orrcon is one of Australia's largest suppliers of steel pipe and tubing. This study of how to stop steel from corroding will produce new breakthroughs in understanding silane chemistry, which is safer, cheaper and more effective in reducing rust, than what is being used today. This new science will benefit Australia's research into corrosion and help us to be more competitive in the export of steel. Our proof of concept studies on the corrosion resistance of new silanes on aerospace aluminium alloys has helped Australian products enter markets where chromium(VI) is now banned. Silicon chemistry is also little researched in Australia and this project will train four new researchers in this field.Read moreRead less
Three-dimensional printing of functional polymers. This project aims to develop methods to three-dimensional (3D) print functional polymer inks to create advanced objects with engineered properties. Additive manufacturing has the ability to transform industries bringing manufacturing into local business and homes. However, for the true potential to be met, innovative polymer inks need to be developed. This project will develop innovative polymer inks as raw materials for affordable 3D printers. ....Three-dimensional printing of functional polymers. This project aims to develop methods to three-dimensional (3D) print functional polymer inks to create advanced objects with engineered properties. Additive manufacturing has the ability to transform industries bringing manufacturing into local business and homes. However, for the true potential to be met, innovative polymer inks need to be developed. This project will develop innovative polymer inks as raw materials for affordable 3D printers. It will prepare a range of polymer inks that respond and change their properties in response to their environment, for example a temperature switch. This will enable printed objects to perform complex tasks such as shape shifting and self-healing.Read moreRead less