Development of dense gas technology platforms for the formulation of oral vaccines. This project will aim to develop a technology platform that enables the formulation of vaccines that can be delivered orally and this research has the potential to radically change existing vaccination regimens. The availability of needle-free vaccination also has potential for considerable societal and economic impact in developing countries.
Gene Expression Profiling and de novo Transcriptome Sequencing using Geneballs. The purpose of the project is to demonstrate that bead-based technology can be used in applications that currently require DNA hybridisation in order to overcome existing deficiencies in microarray technology. By providing the capability to quickly and efficiently produce, screen and utilize biomolecule libraries of nearly unlimited size, this technology provides the key to unlock the power of genomics and proteomics ....Gene Expression Profiling and de novo Transcriptome Sequencing using Geneballs. The purpose of the project is to demonstrate that bead-based technology can be used in applications that currently require DNA hybridisation in order to overcome existing deficiencies in microarray technology. By providing the capability to quickly and efficiently produce, screen and utilize biomolecule libraries of nearly unlimited size, this technology provides the key to unlock the power of genomics and proteomics for use in real world applications. The project has two aspects. First, relatively small directed cDNA-bead libraries will be compared to known low-density cDNA microarrays to validate the technique for utility in gene expression profiling. Secondly, large libraries containing short oligonucleotide sequences will be used for de novo sequencing of a complete transcriptome. Proof-of-concept in either case will pave the way for many genomic applications and catapult the technology to 'blockbuster' status.Read moreRead less
Efficient Dye-Sensitised Solar Cells: New Cathodic Materials and Systems. Accelerating the uptake of renewable energy through new and diverse sources is critical to Australia's commitment to sustainable future, and Australia's energy security. This project will address key issues in commercially emerging Dye Solar Cell (DSC) technology, which has been accepted as a credible avenue to cost effective solar electricity. To date, significant development both in industry and Academia, has resulted in ....Efficient Dye-Sensitised Solar Cells: New Cathodic Materials and Systems. Accelerating the uptake of renewable energy through new and diverse sources is critical to Australia's commitment to sustainable future, and Australia's energy security. This project will address key issues in commercially emerging Dye Solar Cell (DSC) technology, which has been accepted as a credible avenue to cost effective solar electricity. To date, significant development both in industry and Academia, has resulted in Australia's leading and often pioneering position in this field. The project will maintain and enhance this position through both scientific and commercial outcomes, including opening up new markets for flexible DSC and exporting products and technological solutions through commercial activities of the Partner Organisation.Read moreRead less
Development of Effective Bentonite Adsorbents for Colour Removal from Wastewater and Process Streams. This project aims to develop cost-effective adsorbents from natural bentonite clay for the removal of colour organics in water and other process streams. A new method for modifying the clays will be developed and investigated systematically. Adsorption of various dyes onto clay-based adsorbents will be examined to obtain a better understanding of the adsorption equilibrium and kinetics. The proj ....Development of Effective Bentonite Adsorbents for Colour Removal from Wastewater and Process Streams. This project aims to develop cost-effective adsorbents from natural bentonite clay for the removal of colour organics in water and other process streams. A new method for modifying the clays will be developed and investigated systematically. Adsorption of various dyes onto clay-based adsorbents will be examined to obtain a better understanding of the adsorption equilibrium and kinetics. The project will study the effects of various parameters to optimise the processing conditions for maximum removal efficiency. The project contributes to the mineral industry in value-adding and will also lead to cost-effective processes for water pollution control.Read moreRead less
A new nano-sensor technology for the detection and identification of residual vapours of explosives, drugs and chemicals in the air. Fighting terrorism and crime is one of the most important and difficult tasks that requires substantial human and technological resources. This project will help to address this enormous problem by developing a new optical sensor technology for the detection and identification of traces of chemicals, explosives, drugs and biological agents. It will develop a labora ....A new nano-sensor technology for the detection and identification of residual vapours of explosives, drugs and chemicals in the air. Fighting terrorism and crime is one of the most important and difficult tasks that requires substantial human and technological resources. This project will help to address this enormous problem by developing a new optical sensor technology for the detection and identification of traces of chemicals, explosives, drugs and biological agents. It will develop a laboratory prototype of this sensor that is expected to have superior sensitivity and operational capabilities. Thus it will noticeably contribute to practical law enforcement, air quality and environmental monitoring, counter-terrorism, air safety, border security and customs service. It will also lead to further development of nano-optics and nanotechnology in Australia. Read moreRead less
New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a rea ....New nanocomposites of porous materials and visible light sensitive TiO2 for efficient wastewater purification. The innovative newly proposed materials can trap and efficiently decompose dissolved organics in the same process, without generating any waste for disposal. No UV is required and the solar radiation can be efficiently used. The proposed research will be a significant breakthrough in the field of water treatment that reduces energy consumption, uses low cost materials and provides a real solution. The research findings will be useful to a wide spectrum of manufacturing industries which are currently generating slightly contaminated wastewater, and will be beneficial to the community in general. At the same time, the industries will be a step forward toward sustainable manufacturing.Read moreRead less
Nanostrutured Magnesium-base Composites for High-density Hydrogen Storage. This project aims to develop nanocrstalline magnesium-based composites for effective hydrogen storage, overcoming two main technical barriers of current metal hydride systems: high charging/discharging temperature and slow kinetics. Nanoscale catalysts based on mesoporous carbons and metal nanoparticles will be introduced into the magnesium to increase storage capacity and increase the rate at low temperatures. Fundament ....Nanostrutured Magnesium-base Composites for High-density Hydrogen Storage. This project aims to develop nanocrstalline magnesium-based composites for effective hydrogen storage, overcoming two main technical barriers of current metal hydride systems: high charging/discharging temperature and slow kinetics. Nanoscale catalysts based on mesoporous carbons and metal nanoparticles will be introduced into the magnesium to increase storage capacity and increase the rate at low temperatures. Fundamental understanding on the effects of catalysts, and adsorption and desorption mechanisms will be obtained to optimise the composite materials. This project will lead to effective and practical technology for hydrogen storage that will meet the target of commercial fuel cell vehicles.Read moreRead less
An integrated system for high-efficiency hydrogen assisted electricity generation from solar energy. Energy security and climate change have intensified the search for renewable energy technologies that will reduce the carbon footprint of our economies. This project will lead to a technology platform, enabling hydrogen production and electricity generation by a clean way, which is high potential in solar-abundance Australia. Its success will definitely benefit Australia both economically and env ....An integrated system for high-efficiency hydrogen assisted electricity generation from solar energy. Energy security and climate change have intensified the search for renewable energy technologies that will reduce the carbon footprint of our economies. This project will lead to a technology platform, enabling hydrogen production and electricity generation by a clean way, which is high potential in solar-abundance Australia. Its success will definitely benefit Australia both economically and environmentally. It will speed up the utilisation of solar energy and help Australia reduce greenhouse emissions. It would also lead to advanced technologies that can be commercialised and exported overseas, thus positioning Australia at the forefront of renewable energy development.Read moreRead less
Next generation hybrid nanomaterials: bispecific antibody-targeted polymers. This project aims to develop and optimise a novel platform technology that will assist in the development of hybrid materials consisting of nanomaterials and biomolecules, which form the basis of many commercial diagnostic devices. A novel antibody, MIL38, will provide the test bed for the technology, which will aim to deliver a platform that is stable under physiological conditions and that enables facile conjugation o ....Next generation hybrid nanomaterials: bispecific antibody-targeted polymers. This project aims to develop and optimise a novel platform technology that will assist in the development of hybrid materials consisting of nanomaterials and biomolecules, which form the basis of many commercial diagnostic devices. A novel antibody, MIL38, will provide the test bed for the technology, which will aim to deliver a platform that is stable under physiological conditions and that enables facile conjugation of nanomaterials with antibodies. This project has the potential to rapidly improve the ligation process between synthetic nanomaterials and biologics, leading to more efficient synthesis of targeted diagnostics. This would provide a significant commercial advantage for any nanomaterials developed for the field, and specifically for this project, expedite translation of MIL38.Read moreRead less
Kinetics of phytochemical adsorption and desorption in clay nanoparticles. Biologically active phytochemicals are of increasing importance in many areas of human endeavour. There is a growing interest in the agricultural uses of such compounds. A major limiting factor has been the control of the release rate and the general susceptibility to UV breakdown. This project aims to develop a platform technology for the controlled release and for improved UV protection of these chemicals. Through the s ....Kinetics of phytochemical adsorption and desorption in clay nanoparticles. Biologically active phytochemicals are of increasing importance in many areas of human endeavour. There is a growing interest in the agricultural uses of such compounds. A major limiting factor has been the control of the release rate and the general susceptibility to UV breakdown. This project aims to develop a platform technology for the controlled release and for improved UV protection of these chemicals. Through the studies on the adsorption and desorption kinetics of select phytochemicals, we aim to develop a nanoparticle clay based carrier system and a predictive model for control of the desorption characteristics. Such a platform technology will enable wide range of applications of phytochemical products in pesticides, plant stress alleviating and growth enhancing areas.Read moreRead less