The Role Of Capsid Protein Nucleolar Localisation In Chikungunya Virus: Implications For Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$520,520.00
Summary
Chikungunya virus (CHIKV) is a globally widespread mosquito-borne alphavirus capable of causing considerable human morbidity and mortality. With no CHIKV vaccine or antiviral available this proposal aims to develop a live attenuated CHIKV vaccine, rationally designed by investigating the host cell nucleolar trafficking of CHIKV capsid protein. This vaccine has the potential to provide cross-protection against additional arthritogenic alphaviruses endemic to Australia such as Ross River virus.
Industrial Transformation Training Centres - Grant ID: IC230100036
Funder
Australian Research Council
Funding Amount
$4,999,600.00
Summary
ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical ....ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical production, more resilient spacecraft and robust regulatory frameworks. Industries and communities will benefit from a future workforce prepared for safe adoption, development and delivery of emerging techniques and advanced radiation technologies, enhancing Australia’s prosperity and security.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0238631
Funder
Australian Research Council
Funding Amount
$200,000.00
Summary
Ultra High Resolution Electron Recycling Spectrometer. Electron collisions with atoms and molecules provide enormous versatility through the transfer of large amounts of angular momentum and the ability to excite dipole forbidden states. However a lack of energy resolution severely restricts the processes that can be studied.
We propose to construct a unique, ultra-high resolution, electron recycling spectrometer using a radical new design. State-of-the-art spectroscopic studies of ato ....Ultra High Resolution Electron Recycling Spectrometer. Electron collisions with atoms and molecules provide enormous versatility through the transfer of large amounts of angular momentum and the ability to excite dipole forbidden states. However a lack of energy resolution severely restricts the processes that can be studied.
We propose to construct a unique, ultra-high resolution, electron recycling spectrometer using a radical new design. State-of-the-art spectroscopic studies of atoms and molecules will be enabled, including the dynamics of near-threshold processes, the formation of transient states and the examination of processes such as rotational excitation and dissociative attachment in molecules - important in a number of gas-discharge based devices.
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ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting- ....ARC Centre of Excellence for Dark Matter Particle Physics. The Centre of Excellence for Dark Matter Particle Physics will deliver breakthroughs in our understanding of the Universe through the pursuit of the discovery of dark matter particles which comprise 80% of the mass of the universe. It assembles for the first time a strong and diverse team of physicists from particle, nuclear, and quantum physics as well as particle astrophysics. It will deliver high-profile experiments using new cutting-edge technologies. The Centre will exploit the unique geographical location of the first underground physics lab in the Southern Hemisphere. The ultra-sensitive detectors and ultra-low radiation techniques will translate into a broad range of industrial applications and train a new generation of scientists.Read moreRead less
Atomic Ionization on the Attosecond Time Scale. Electrons emit light, carry electric current, and bind atoms together to form molecules. Insight into their atomic-scale motion is the key to understanding the functioning of biological systems, developing efficient sources of x-ray light, and speeding up electronics. Capturing this electron motion requires attosecond (one quintillionth of a second) time resolution. Our research aims to understand and accurately model fundamental atomic processes ....Atomic Ionization on the Attosecond Time Scale. Electrons emit light, carry electric current, and bind atoms together to form molecules. Insight into their atomic-scale motion is the key to understanding the functioning of biological systems, developing efficient sources of x-ray light, and speeding up electronics. Capturing this electron motion requires attosecond (one quintillionth of a second) time resolution. Our research aims to understand and accurately model fundamental atomic processes taking place on the attosecond time scale. This research project will further enhance our reputation in an area where Australian theorists are preeminent, and the research training will produce PhD graduates with the skills essential in a multitude of nano-technology applications. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453842
Funder
Australian Research Council
Funding Amount
$590,309.00
Summary
National Facility for Electron Spin Correlations and Spintronics. Conventional electronics is based on coupling the charge of the electrons with external electric fields and light. Recent work on spintronics is directed toward the use of both the spin (angular momentum) and the charge degrees of freedom of the electron. We currently lead the world in the development of spin-resolved coincidence measurements, which make it possible to determine previously inaccessible nanoscale magnetic propertie ....National Facility for Electron Spin Correlations and Spintronics. Conventional electronics is based on coupling the charge of the electrons with external electric fields and light. Recent work on spintronics is directed toward the use of both the spin (angular momentum) and the charge degrees of freedom of the electron. We currently lead the world in the development of spin-resolved coincidence measurements, which make it possible to determine previously inaccessible nanoscale magnetic properties, central to 'spintronic structure engineering'. State-of-the-art instrumentation is requested to characterise the magnetic and crystallographic structure, the adsorbates, and the lateral distribution and depth profile of fabricated zero, one and two-dimensional structures.Read moreRead less
ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies ....ARC Centre of Excellence - Centre for Antimatter-Matter Studies. While our world is made of matter, all particles have anti-particles and the most abundant is the positron, the electron's antiparticle. It is the "workshop" for most anti-matter studies, particularly for the characterization of materials, including gases, polymers, insulators, thin films and surfaces, as well as the development of new and novel, nano-structured materials. The ARC Centre of Excellence in Antimatter-Matter Studies (CAMS) will bring together key Australian and international scientists to work in this emerging scientific field of antimatter-matter interactions. It will forge a unique and effective scientific team for state-of-the-art studies of the nano-world that underlies many everyday processes and new technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100054
Funder
Australian Research Council
Funding Amount
$824,080.00
Summary
Facility for electric and magnetic probes of materials at extreme conditions. This project aims to establish a readily accessible facility for measurement of electric and magnetic properties of materials under extreme temperature, magnetic field, and sensitivity conditions. The expected outcome is to build capacity for and support world-leading research into novel topological materials, atomically thin materials, materials with strong light-matter interactions and magnetic materials. The benefit ....Facility for electric and magnetic probes of materials at extreme conditions. This project aims to establish a readily accessible facility for measurement of electric and magnetic properties of materials under extreme temperature, magnetic field, and sensitivity conditions. The expected outcome is to build capacity for and support world-leading research into novel topological materials, atomically thin materials, materials with strong light-matter interactions and magnetic materials. The benefits to society are new devices for efficient generation, storage, transmission and switching of energy.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100151
Funder
Australian Research Council
Funding Amount
$760,000.00
Summary
Probe and engineer interactions in atomic-scale devices with a LT STM. A low-temperature scanning tunnelling microscope: The project aims to establish a facility to exploit the spectroscopic and spatial resolution of an ultra-low temperature scanning tunnelling microscope in conjunction with atomically controlled dopant engineering. In a variety of experiments the research team will explore ultra-scaled transistors, quantum information science devices, and engineered quantum matter. Improving ou ....Probe and engineer interactions in atomic-scale devices with a LT STM. A low-temperature scanning tunnelling microscope: The project aims to establish a facility to exploit the spectroscopic and spatial resolution of an ultra-low temperature scanning tunnelling microscope in conjunction with atomically controlled dopant engineering. In a variety of experiments the research team will explore ultra-scaled transistors, quantum information science devices, and engineered quantum matter. Improving our ability to investigate semiconductor materials at the atomic scale impacts fields ranging from electronics, telecommunication, quantum information to renewable energy research and puts Australia at the forefront of the field of controlled atomic systems in semiconductors.Read moreRead less