Target Of Rapamycin control of nutrient uptake. This project aims to study nutrient uptake in eukaryotes. It is expected to generate new knowledge of critical and conserved features of environmental and Target Of Rapamycin (TOR)-mediated control of nutrient uptake, specifically endocytosis, building on novel preliminary data that identifies novel TOR control points. The expected outcomes include new insights into mechanisms controlling nutrient uptake and fostering institutional collaboration. T ....Target Of Rapamycin control of nutrient uptake. This project aims to study nutrient uptake in eukaryotes. It is expected to generate new knowledge of critical and conserved features of environmental and Target Of Rapamycin (TOR)-mediated control of nutrient uptake, specifically endocytosis, building on novel preliminary data that identifies novel TOR control points. The expected outcomes include new insights into mechanisms controlling nutrient uptake and fostering institutional collaboration. This knowledge is highly relevant to any industry or research project utilising living organisms, as nutrient availability supports survival, cell growth and proliferation.Read moreRead less
How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent si ....How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent signaling. Expected outcomes include novel insights into environmental control of cell proliferation and forging cross institutional collaborations. This knowledge benefits basic and applied biology and is relevant to industries/projects utilizing living cells as nutrient supports cell survival and proliferation.Read moreRead less
Engineered topological nanostructures – a new frontier in materials design. The aim of engineering and utilising topological defects such as domain walls and and skyrmions in functional materials is currently receiving tremendous attention. Their significance lies in a plethora of fascinating phenomena for fundamental research and future technological applications in nanoelectronics. One frontier area of research is negative capacitance nanoelectronics using such materials, carrying the prospect ....Engineered topological nanostructures – a new frontier in materials design. The aim of engineering and utilising topological defects such as domain walls and and skyrmions in functional materials is currently receiving tremendous attention. Their significance lies in a plethora of fascinating phenomena for fundamental research and future technological applications in nanoelectronics. One frontier area of research is negative capacitance nanoelectronics using such materials, carrying the prospect of revolutionizing ultralow energy electronics, which will be developed here. The project's expected outcomes are new concepts for the synthesis and design of topological nanostructures for such applications. The utilization of these materials will benefit efficient controllable functionality for future nanoelectronics.Read moreRead less