Nanostructure engineered low activation superconductors for fusion energy. This project aims to develop a novel, low activation and liquid helium-free superconducting solution with superior electromagnetic, mechanical and thermal properties for use in fusion reactors. Superconducting magnets and their associated cryogenic cooling systems represent a key determinant of thermal efficiency and the construction/operating costs of fusion reactors. The project expects to overcome these barriers so tha ....Nanostructure engineered low activation superconductors for fusion energy. This project aims to develop a novel, low activation and liquid helium-free superconducting solution with superior electromagnetic, mechanical and thermal properties for use in fusion reactors. Superconducting magnets and their associated cryogenic cooling systems represent a key determinant of thermal efficiency and the construction/operating costs of fusion reactors. The project expects to overcome these barriers so that widespread uptake of these reactors becomes viable. Outcomes from the project will include a fundamental understanding of pure and doping-induced isotopic magnesium diboride superconductors and their behaviour under high neutron flux and harsh plasma atmosphere, which are specifically designed for application in next-generation, low-cost fusion reactors.Read moreRead less
Role Of IGF Binding Protein-3 (IGFBP-3) And IGFBP-5 As Modulators Of Nuclear Hormone Signalling
Funder
National Health and Medical Research Council
Funding Amount
$465,750.00
Summary
The insulin-like growth factors are small proteins involved in the growth of most tissues. Their actions are regulated by binding to larger proteins (known as IGFBPs) in the bloodstream and outside the cell. However, some IGFBPs are also found inside cells, where they seem to carry out other functions. We believe that two of these binding proteins, IGFBP-3 and IGFBP-5, change the way cells respond to vitamin A and vitamin D. These two vitamins are important in cell growth and in the way certain ....The insulin-like growth factors are small proteins involved in the growth of most tissues. Their actions are regulated by binding to larger proteins (known as IGFBPs) in the bloodstream and outside the cell. However, some IGFBPs are also found inside cells, where they seem to carry out other functions. We believe that two of these binding proteins, IGFBP-3 and IGFBP-5, change the way cells respond to vitamin A and vitamin D. These two vitamins are important in cell growth and in the way certain cells perform specialised functions. In test-tube experiments, IGFBP-3 and IGFBP-5 interact directly with the receptors that regulate the effects of these hormones. If the same thing happens inside the cell, IGFBP-3 and IGFBP-5 could change the way these receptors respond to signals from outside the cell. We will investigate what effect these IGFBPs have in living cells and in whole animals and how this may relate to human disease. If we are able to understand how IGFBP-3 and IGFBP-5 affect the way cells respond to vitamin A and D, then we may be able to develop new ways to treat certain human diseases.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC230100036
Funder
Australian Research Council
Funding Amount
$4,999,600.00
Summary
ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical ....ARC Training Centre for Radiation Innovation. This Centre aims to train the next generation of transdisciplinary leaders to enable, grow and transform industries that utilise or are impacted by radiation. Rapid growth in the natural resources, health, space and national security sectors urgently requires a highly capable workforce with scientific and regulatory knowledge to develop new technologies and social licence needs to maximise benefits. Outcomes include new methods of radiopharmaceutical production, more resilient spacecraft and robust regulatory frameworks. Industries and communities will benefit from a future workforce prepared for safe adoption, development and delivery of emerging techniques and advanced radiation technologies, enhancing Australia’s prosperity and security.Read moreRead less
Molecular Regulation Of Metabolism And Body Composition By Ski Via Crosstalk With Nuclear Hormone Receptor Signalling.
Funder
National Health and Medical Research Council
Funding Amount
$558,441.00
Summary
Obesity is a common and burdensome health problem in the community which leads to diabetes and heart disease. A number of factors, including hormones play important roles in determing risk of obesity. This study proposes to investigate whether the Ski gene which is a regulatory factor for many hormones affects metabolism in transgenic mouse models of altered Ski function. The proposed studies may identify Ski as a target for therapy for obesity and improvement in sketal muscle metabolism.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882224
Funder
Australian Research Council
Funding Amount
$440,000.00
Summary
Vector Magnetic Field Facility for Nanoscale Spintronic Materials and Device Research. Electronic devices underpin a trillion dollar industry worldwide and are an essential part of modern life. Spintronics (spin-electronics) is an emergent technology that combines the electrical and magnetic properties of electrons to represent and process information. Spintronic chips are expected to be fast, versatile, capable of simultaneous data storage and processing, while at the same time consuming less ....Vector Magnetic Field Facility for Nanoscale Spintronic Materials and Device Research. Electronic devices underpin a trillion dollar industry worldwide and are an essential part of modern life. Spintronics (spin-electronics) is an emergent technology that combines the electrical and magnetic properties of electrons to represent and process information. Spintronic chips are expected to be fast, versatile, capable of simultaneous data storage and processing, while at the same time consuming less energy. Industry analysts suggest the spintronic market will exceed $10 billion. This facility will provide the critical infrastructure needed to study the electronic and magnetic properties of nanostructured materials, providing the underpinning knowledge to develop the next generation of spintronic devices.Read moreRead less
Nonlinear quantum science with superconducting circuit quantum-electrodynamics. Circuit quantum electrodynamics has rapidly emerged in recent years as a new field of experimental quantum science, with applications to precision measurement, nanomechanical transducers and quantum information processing. We will design and demonstrate new experimental devices, grounded in a long-standing expertise in quantum optics, and enabled by a new low temperature laboratory under development at The Universit ....Nonlinear quantum science with superconducting circuit quantum-electrodynamics. Circuit quantum electrodynamics has rapidly emerged in recent years as a new field of experimental quantum science, with applications to precision measurement, nanomechanical transducers and quantum information processing. We will design and demonstrate new experimental devices, grounded in a long-standing expertise in quantum optics, and enabled by a new low temperature laboratory under development at The University of Queensland. This project will deliver a new technological capability for Australia.Read moreRead less
Modelling quantum dynamics of electronic excited states in complex molecular materials. Understanding new materials that are the basis of new sources of renewable energy sources represents a major scientific challenge. Many of these materials are composed of large organic molecules containing hundreds of atoms. Their properties and the concepts needed to understand these materials are distinctly different from semiconductors such as silicon. This research will enhance our ability to design bett ....Modelling quantum dynamics of electronic excited states in complex molecular materials. Understanding new materials that are the basis of new sources of renewable energy sources represents a major scientific challenge. Many of these materials are composed of large organic molecules containing hundreds of atoms. Their properties and the concepts needed to understand these materials are distinctly different from semiconductors such as silicon. This research will enhance our ability to design better materials and optimize the performance of organic solar cells and LEDs. Australia's capacity for research and development in this scientifically challenging and technologically important field will be enhanced by this project. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100060
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
High pressure facility for optical spectroscopy: investigation of novel superconductors and strongly correlated electron systems. Superconductivity is an effect where the electrical resistance disappears completely at low temperatures. This facility will permit optical spectroscopy under high hydrostatic pressure to reveal important new information leading to a deeper understanding of this effect.
Low-cost, Lightweight and Liquid Helium-free Superconducting MRI Magnet. This project aims to develop a liquid-helium-free superconducting technology to address the need for more affordable MRI magnets that currently rely on expensive, limited supplies of liquid helium. This project expects to generate a world-first, much needed MRI systems to be operated in persistent mode without a power supply, to obtain high-resolution images and low-cost operation. The expected outcomes include a novel, lig ....Low-cost, Lightweight and Liquid Helium-free Superconducting MRI Magnet. This project aims to develop a liquid-helium-free superconducting technology to address the need for more affordable MRI magnets that currently rely on expensive, limited supplies of liquid helium. This project expects to generate a world-first, much needed MRI systems to be operated in persistent mode without a power supply, to obtain high-resolution images and low-cost operation. The expected outcomes include a novel, lightweight, easy-to-operate magnesium diboride superconducting MRI magnet prototype under persistent mode operation. This should provide significant benefits, including reducing the cost associated with conventional liquid helium-dependent technologies and ensuring Australia at the forefront of MRI development worldwide.Read moreRead less