Non-invasive Detection Of Hypoglycaemia In People With Diabetes Using Brain Wave Activity
Funder
National Health and Medical Research Council
Funding Amount
$330,447.00
Summary
Hypoglycaemia remains a major cause of morbidity and mortality in people with both type 1 diabetes and type 2 diabetes who require insulin therapy. Current treatments for nocturnal hypoglycaemia are usually ineffective. Combining brain wave recording and artificial intelligence, we will identify the changes that precipitate an episode of hypoglycaemia allowing the development of a non-invasive device to prevent or alleviate these fearful and potentially life-threatening events.
Social buffering of fear inhibition in adolescent rats. Adolescence is an important time when individuals learn to manage stress-related emotions like fear. Peers can help, or hinder, individuals to regulate fear. This project aims to understand how, when, and for whom social buffering of fear regulation occurs during adolescence. It uses a behavioural, pharmacological, and neural approach to explore these issues. The project aims to close the gap in understanding of how social companions affect ....Social buffering of fear inhibition in adolescent rats. Adolescence is an important time when individuals learn to manage stress-related emotions like fear. Peers can help, or hinder, individuals to regulate fear. This project aims to understand how, when, and for whom social buffering of fear regulation occurs during adolescence. It uses a behavioural, pharmacological, and neural approach to explore these issues. The project aims to close the gap in understanding of how social companions affect basic learning and memory processes in an understudied population of adolescents. The expected outcomes of this project include a richer knowledge of how peers shape emotional regulation during development, which will ultimately inform social-based approaches for improving emotion regulation in youth.
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A Systematic Evaluation Of The Neurosurgical Application Of Peri-operative And Intra-operative MR Tractography In Different Paediatric Disease States
Funder
National Health and Medical Research Council
Funding Amount
$130,910.00
Summary
My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve whit ....My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve white matter lesion localisation.Read moreRead less
Efficacy Of Prism Adaptation For Recovery Of Brain Function In Unilateral Spatial Neglect
Funder
National Health and Medical Research Council
Funding Amount
$531,690.00
Summary
Damage to the brain’s attention network causes profound impairments of visual and sensory perception. These deficits are frequently long-lasting, and are a major factor in preventing patients from regaining functional independence. This project will use a combination of behavioural and brain imaging techniques to determine whether a promising new treatment involving visual retraining can improve function and reduce perceptual impairments after unilateral brain lesions.
Efficacy Of A 3-month Aerobic Exercise Regime For Restoring 'brain Health' In Heavy Cannabis Users
Funder
National Health and Medical Research Council
Funding Amount
$1,209,221.00
Summary
Over a ten-year period, we, and others have documented the brain and psychological harms associated with regular cannabis use. We have now shown that these harms are not permanent, but can be restored. However, the recovery process takes a long time. This study will build on our extensive work to date and, for the first time, investigate whether a specific form of exercise will cause accelerated and beneficial changes in i) the brain and ii) the daily lives of heavy cannabis users.
Australian Laureate Fellowships - Grant ID: FL220100184
Funder
Australian Research Council
Funding Amount
$2,897,256.00
Summary
Next-generation maps and models of the human brain. This project aims to develop a new framework for understanding how the anatomy of the brain shapes its function and influences individual differences in human behaviour. The project expects to develop innovative methods for mapping and modelling human brain function by combining techniques from neuroscience, physics, informatics, psychology, and genetics. Expected outcomes include new tools for analysing brain imaging data, new models of brain ....Next-generation maps and models of the human brain. This project aims to develop a new framework for understanding how the anatomy of the brain shapes its function and influences individual differences in human behaviour. The project expects to develop innovative methods for mapping and modelling human brain function by combining techniques from neuroscience, physics, informatics, psychology, and genetics. Expected outcomes include new tools for analysing brain imaging data, new models of brain structure and function, an understanding of how genes shape brain architecture, and a comprehensive characterization of how individual differences in brain organization relate to behaviour. These outcomes should benefit our understanding of how the brain works and of the biological basis of behaviour.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100498
Funder
Australian Research Council
Funding Amount
$453,868.00
Summary
Mapping the genetics of brain connectivity. The brain is a complex biological system that gives rise to our consciousness, thoughts, and experiences, yet we still do not know how this complexity emerges. This project aims to comprehensively investigate the genetics of brain connectivity combining cutting-edge techniques in neuroimaging, genomics, mathematical modelling, and cognitive neuroscience, focusing specifically on the connectivity of functionally important brain network hubs. The outcome ....Mapping the genetics of brain connectivity. The brain is a complex biological system that gives rise to our consciousness, thoughts, and experiences, yet we still do not know how this complexity emerges. This project aims to comprehensively investigate the genetics of brain connectivity combining cutting-edge techniques in neuroimaging, genomics, mathematical modelling, and cognitive neuroscience, focusing specifically on the connectivity of functionally important brain network hubs. The outcomes will provide a mechanistic understanding of the genetic origins of brain network formation and an explanation for how genetic influences on brain organisation shape human behaviour advancing the fundamental knowledge about the complexity of the brain.Read moreRead less
Does Antipsychotic Dose Reduction Lead To Better Functional Recovery In First Episode Psychosis: A Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$2,371,552.00
Summary
Can a person with a first episode of psychosis, once remitted, reduce their dosage of medication and still achieve better outcomes in functioning, physical health and brain volume, than if they had stayed on traditional maintenance doses of medication? This study will examine if using a dose reduction strategy in conjunction with an evidence based suite of psychosocial interventions leads to better social and vocational recovery and improved physical health and brain volume.