Functional Neuroimaging In Mild Traumatic Brain Injury
Funder
National Health and Medical Research Council
Funding Amount
$176,719.00
Summary
Mild traumatic brain injury (mTBI) represents a significant public health issue in Australian communities. Complications can include prolonged symptoms, depression and progressive deterioration of brain function. Clinical management of mTBI hinges on accurate assessment of recovery. The aim of the current study is to investigate the role of novel functional brain imaging techniques such as diffusion tensor imaging and connectivity studies, in the assessment of brain disturbance following mTBI.
Cerebral Palsy In Victoria: A Population-based Study
Funder
National Health and Medical Research Council
Funding Amount
$107,990.00
Summary
This research project is broad in its exploration of cerebral palsy in Victoria. It will contribute to the global pool of knowledge by addressing a number of unanswered questions, such as whether the overall rates of cerebral palsy are changing over time, an important indicator of the effect of changes in medical management strategies for pregnancy and newborns. Recognition of patterns of brain abnormalities and other risk factors play an important role in the identification of causal pathways.
Neuronal Copper Homeostasis And The Role Of The Alzheimer Amyloid-Beta Precursor Protein (APP)
Funder
National Health and Medical Research Council
Funding Amount
$287,321.00
Summary
Alzheimer’s disease (AD) is creating a growing burden upon Australian medical resources. Copper plays an important role in the development of AD and drugs designed to adjust brain copper levels are being tested for AD treatment and show therapeutic benefits. This project will determine how copper is involved in AD so that more effective drugs can be developed. Focus will primarily be on copper-binding proteins central to AD and establishing their role in AD development and progression.
TDP-43 In The Population In Relation To Dementia: Relationships With Clinical Symptomatology And Other Key Neuropathologies
Funder
National Health and Medical Research Council
Funding Amount
$235,002.00
Summary
There are over a quarter of a million people with dementia in Australia, and this figure will rise. We still do not understand what goes wrong within the brain to give rise to dementia. This project will assess a new pathology within the brain in relation to late life dementia and the aging process. Results will improve diagnostic tools for dementia and treatments.
Alzheimer's Disease And Dementia With Lewy Bodies: How Different Are They?
Funder
National Health and Medical Research Council
Funding Amount
$565,500.00
Summary
Dementia is a devastating disorder, taking the individuals mind. As the population ages, a significant proportion become demented, impacting on these individuals, their families and the community as a whole (Federal and State budgets for this disorder are costed in the billions). There are many cellular causes of dementia, the most frequent being considered Alzheimer's disease. However, many people currently thought to have Alzheimer's disease have another dementia cause - dementia with Lewy bod ....Dementia is a devastating disorder, taking the individuals mind. As the population ages, a significant proportion become demented, impacting on these individuals, their families and the community as a whole (Federal and State budgets for this disorder are costed in the billions). There are many cellular causes of dementia, the most frequent being considered Alzheimer's disease. However, many people currently thought to have Alzheimer's disease have another dementia cause - dementia with Lewy bodies. This study aims to determine 1) how common these two types of dementias are (currently unknown) 2) how better to diagnose them and tell them apart 3) how badly the brain is affected by each disorder and 4) whether the same genes are involved in both disorders. The knowledge we will gain will allow better diagnosis of the cellular causes of dementia, knowledge necessary for rational treatment.Read moreRead less