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The hidden secondary metabolite biosynthetic potential of fungi. This proposal aims to develop synthetic biology tools to allow rapid access to the hidden metabolites encoded in fungal genomes and discover how they interact with plant and animal hosts. Genome sequencing reveals that fungi harbour vast hidden potential for biosynthesis of bioactive small molecules. The lack of tools to efficiently access this hidden potential has hindered the ability to develop this uncharted chemical diversity f ....The hidden secondary metabolite biosynthetic potential of fungi. This proposal aims to develop synthetic biology tools to allow rapid access to the hidden metabolites encoded in fungal genomes and discover how they interact with plant and animal hosts. Genome sequencing reveals that fungi harbour vast hidden potential for biosynthesis of bioactive small molecules. The lack of tools to efficiently access this hidden potential has hindered the ability to develop this uncharted chemical diversity for pharmaceutics and agriculture, and understand their biological roles in pathogens. Expected outcomes include sources of bioactive molecules and better management of fungal diseases in crops and humans.Read moreRead less
Special Research Initiatives - Grant ID: SR0354575
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and me ....Earth and Ocean Informatics and Technology Network (EON-ITnet). Sustainable resource exploration and mining onshore, as well as marine planning, exploration, and defence depend on effective cross-disciplinary investigation, sharing of expertise and technologies for integration and computational analysis of multidimensional data spaces. EON-ITNET will cross-fertilise the use of artificial intelligence, advanced computing and smart information sharing for management, analysis, visualisation and metadata modelling between these traditionally separate research groups, with the outcome of improving research efficiency and lowering costs. EON-ITNET will form an alliance with the Caltech-based GeoFramework, which is advancing a novel object-oriented data analysis environment, binding community software for Earth visualisation and simulation to 4D data bases.Read moreRead less
ARC Australia-New Zealand Research Network for Vegetation Function. Plant species vary widely in quantitative functional traits, and in their relations to climate, soils and geography. Global generalizations are emerging. Vegetation Function network will reach from plant function into genomics and crop breeding, into palaeoecology and vegetation history, into landscape management for carbon, water and salinity outcomes, into forecasting future ecosystems under global change, and into phylogeny, ....ARC Australia-New Zealand Research Network for Vegetation Function. Plant species vary widely in quantitative functional traits, and in their relations to climate, soils and geography. Global generalizations are emerging. Vegetation Function network will reach from plant function into genomics and crop breeding, into palaeoecology and vegetation history, into landscape management for carbon, water and salinity outcomes, into forecasting future ecosystems under global change, and into phylogeny, ecoinformatics and evolutionary theory. Across this span, working groups will target nine identified opportunities for breakthrough research. Each research target needs input from two or more disciplines. Together, the nine targets link across disciplines, as a network that spans from genomic to planetary scales.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100061
Funder
Australian Research Council
Funding Amount
$285,000.00
Summary
A new seismic facility for investigating tectonic collision zones, earthquake hazards and passive imaging techniques. A new seismic facility will enable collaboration with overseas partners to better understand plate margin tectonics and earthquake hazard in our region for mutual benefit. It will also be used in pilot studies of areas endowed with deep earth resources, and in assessing regions of heightened earthquake activity in Australia.
Industrial Transformation Training Centres - Grant ID: IC190100031
Funder
Australian Research Council
Funding Amount
$3,973,202.00
Summary
ARC Training Centre in Data Analytics for Resources and Environments (DARE). Understanding the cumulative impact of actions regarding the use of our resources has important long-term consequences for Australia’s economic, societal and environmental health. Yet despite the importance of these cumulative impacts, and the availability of data, many decisions and policies are based on limited amounts of data and rudimentary data analysis, with little appreciation of the critical role that understand ....ARC Training Centre in Data Analytics for Resources and Environments (DARE). Understanding the cumulative impact of actions regarding the use of our resources has important long-term consequences for Australia’s economic, societal and environmental health. Yet despite the importance of these cumulative impacts, and the availability of data, many decisions and policies are based on limited amounts of data and rudimentary data analysis, with little appreciation of the critical role that understanding and quantifying uncertainty plays in the process. The aim of Data Analytics in Resources and Environment (DARE) is to develop and deliver the data science skills and tools for Australia’s resource industries to make the best possible evidence-based decisions in exploiting and stewarding the nation’s natural resources.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561229
Funder
Australian Research Council
Funding Amount
$518,427.00
Summary
Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at V ....Establishment of a Multiphoton Microscope Imaging Platform for Live Cell and Tissue, and Optical Imaging. This proposal seeks to establish a multidisciplinary multiphoton imaging laboratory, expanding the imaging capabilities of a Core Regional Imaging Facility. This Facility supports researchers across all Monash campuses and hospital-based research Schools, as well as outside research groups in the Victorian region. Furthermore, this equipment will support significant fiber optic research at Victoria University for the development of communication and endoscopic technology. The instrument design will allow multiple use of the lightsource and choice of specific imaging devices (microscopes) to ensure that applications in biocellular imaging, intravital microscopy and fiber optic design and imaging are individually optimised.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100023
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Functional and Sustainable Fibres. This Research Hub aims to expand Australia’s position in fibres, textiles and composites by developing next generation functional fibre materials and creating synergy between functionality and sustainability, two key attributes that have hitherto been mutually exclusive. The Hub will transform regional and national economies from traditional manufacturing to a vibrant future fibre oriented advanced manufacturing sector with functionality an ....ARC Research Hub for Functional and Sustainable Fibres. This Research Hub aims to expand Australia’s position in fibres, textiles and composites by developing next generation functional fibre materials and creating synergy between functionality and sustainability, two key attributes that have hitherto been mutually exclusive. The Hub will transform regional and national economies from traditional manufacturing to a vibrant future fibre oriented advanced manufacturing sector with functionality and sustainability as central tenets. Expected outcomes include industry adoption of novel fibre-based materials, processing and recycling technologies; creating jobs, significant environmental benefits, and positioning Australia at the front of a global shift towards functional and sustainable materials.Read moreRead less
Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining ....Optimising seed sourcing for effective ecological restoration. This project aims to address the sourcing of native seed for ecological restoration under global change. The great demand for native seed to deliver ecological restoration provides a clear need and responsibility to use this seed as efficiently as possible. This project expects to develop detailed new knowledge that links plant and environmental genomics, plant physiology, seed and soil biology in embedded experiments at post-mining rehabilitation sites. Expected outcomes include clear industry guidelines that refine seed sourcing strategies for ecological restoration for current and future climates. This should provide significant benefits for improved ecological restoration outcomes when using native seed today and into the future.Read moreRead less
Special Research Initiatives - Grant ID: SR0354677
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Sustainable terrestrial and riverine systems through integrated assessment and modelling. Australia must take the lead internationally in sustainability assessment and management; it hosts both the problems and expertise, and is proactive in integrating research and management. This Initiative unites, for the first time, leading researchers from all relevant disciplines to advance our knowledge for achieving sustainable terrestrial and riverine systems (STARS). The intended network can produce a ....Sustainable terrestrial and riverine systems through integrated assessment and modelling. Australia must take the lead internationally in sustainability assessment and management; it hosts both the problems and expertise, and is proactive in integrating research and management. This Initiative unites, for the first time, leading researchers from all relevant disciplines to advance our knowledge for achieving sustainable terrestrial and riverine systems (STARS). The intended network can produce assessments, strategies and policy directions that are objective, adaptive and inclusive. It can evaluate trade-offs between sustainability strategies, integrating research and outcomes, making them accessible to managers. It will build a coordinated research capability that directly supports Australia's goal of ecologically sustainable development. Read moreRead less