From Fundamental Mechanistic Discoveries To Strategic Methods For Early Detection And Treatment Of Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$412,419.00
Summary
I am an interventional cardiologist whose research program spans from biomedical discovery, to new markers of early cardiovascular disease and clinical trials of new therapy. We are particularly focused on novel strategies to help patients who suffer from heart attack despite having no standard risk factors. I lead a team of cross-disciplinary researchers. A Practitioner Fellowship will help me to achieve international impact against the leading cause of death and disability in our community.
Atrial fibrillation is the most common heart rhythm disturbance with a prevalence of approximately 1% but which increases markedly with age. It causes debilitating symptoms, heart failure, stroke and increased mortality. It is an important determinant of neuro-cognitive decline and dementia. The studies in this proposal will help define the mechanism of this rhythm disturbance and its associated symptoms. They will help design improved treatment strategies including interventional approaches.