Identification Of Genes For X-linked Mental Retardation.
Funder
National Health and Medical Research Council
Funding Amount
$675,228.00
Summary
We propose to identify novel heritable causes of intellectual disability using 22 large and well-characterised families from Australia. In these families we have refined the location of the genetic defect to the chromosome X and excluded the contribution of all so far known genes. We will achieve this using the technology of massive parallel sequencing. At the completion of the project we will have identified novel causes of intellectual disability and devised tests to identify them.
Understanding The Risk Factors And Burden Of Heart Disease And Stroke For Aboriginal And Torres Strait Islander Women
Funder
National Health and Medical Research Council
Funding Amount
$86,117.00
Summary
Heart disease and stroke is the leading cause of death for Aboriginal and Torres Strait Islander people, and accounts for over one quarter in the life expectancy gap. A recent survey found that 59% of Aboriginal and Torres Strait Islander women live with heart disease or stroke. This PhD seeks to understand the risks of, and hospitalisation and mortality from heart disease and stroke in Aboriginal and Torres Strait Islander women. The project is guided by a women’s Advisory Group.
Health Impacts Of Sleep Apnea In Australian Men- A Longitudinal Population Study.
Funder
National Health and Medical Research Council
Funding Amount
$312,056.00
Summary
Obstructive sleep apnea (OSA) is very common, seen in 60-70% of men over 40 years old. OSA is linked to a number of serious conditions, e.g. heart disease and diabetes. However, we don't know which men are at risk of long term complications from OSA. Our aim is to follow-up men from a community sample of 1000 men who had sleep studies in 2010 to help identify who is at risk of poor health from OSA.
Linking Place To Metabolic Syndrome Via Behavioural And Psychological Antecedents: Levers For Public Health Intervention
Funder
National Health and Medical Research Council
Funding Amount
$295,135.00
Summary
This collaboration involves the SA Health Department and community partners in analyses of local data from a 10-year biomedical cohort to (i) identify features of residential areas that are related to the metabolic syndrome and (ii) assess the mechanism by which area features influence metabolic syndrome through effects on behavioural and psychosocial mediators. The knowledge generated will inform policy intervention via urban planning and public health actions to support healthful lifestyles.
MICROSCALE PLANKTON AND PARTICLE DYNAMICS: COMPARING AND CONTRASTING AUSTRALIAN AND INTERNATIONAL SEAS. Microscopic phytoplankton are the basis of ocean ecosystems, but most predictions and measurements focus on processes that occur over kilometres. Our recent work shows that definite and regular submetre seascape topography exists. This grant will test the extent to which this seascape topography is the fundamental organisational unit of marine ecosystems and the extent to which it characteris ....MICROSCALE PLANKTON AND PARTICLE DYNAMICS: COMPARING AND CONTRASTING AUSTRALIAN AND INTERNATIONAL SEAS. Microscopic phytoplankton are the basis of ocean ecosystems, but most predictions and measurements focus on processes that occur over kilometres. Our recent work shows that definite and regular submetre seascape topography exists. This grant will test the extent to which this seascape topography is the fundamental organisational unit of marine ecosystems and the extent to which it characterises Australian coastal waters and open ocean water masses. This research takes a leadership role in defining and advancing our understanding of how marine ecosystems function. The project will bring over $200 million of Japanese infrastructure to Australia for 3 years.Read moreRead less
Mathematical models for water management systems. The Australian community is currently talking about schemes to return water to the Murray-Darling river system to combat increased salinity and dramatically reduced river flow. Many believe that vastly improved water management policies are essential to maintain agricultural well-being in Australia. Salinity and water quality depend directly on flow rates and are also important in smaller catchments. In this study we will use statistical rainf ....Mathematical models for water management systems. The Australian community is currently talking about schemes to return water to the Murray-Darling river system to combat increased salinity and dramatically reduced river flow. Many believe that vastly improved water management policies are essential to maintain agricultural well-being in Australia. Salinity and water quality depend directly on flow rates and are also important in smaller catchments. In this study we will use statistical rainfall models and stochastic dynamic programming to find practical water management policies that minimise the risk to water supply. We will develop an interactive simulation and management tool using a modern computer graphics package.Read moreRead less
A graphical simulation package for optimal management and risk assessment in urban stormwater harvesting systems. We will develop a Scalar Vector Graphics (SVG) simulation tool for optimal management and risk assessment in urban stormwater harvesting and utilisation schemes. The generic model will be applied to existing and proposed schemes within the City of Salisbury (CoS) and will include a capture dam, one or more storage dams and an aquifer storage and recovery (ASR) facility. The discret ....A graphical simulation package for optimal management and risk assessment in urban stormwater harvesting systems. We will develop a Scalar Vector Graphics (SVG) simulation tool for optimal management and risk assessment in urban stormwater harvesting and utilisation schemes. The generic model will be applied to existing and proposed schemes within the City of Salisbury (CoS) and will include a capture dam, one or more storage dams and an aquifer storage and recovery (ASR) facility. The discrete state vector will be the content of each storage unit and the daily transition will be driven by a new stochastic rainfall model (SRM). The objective will be to find a practical management policy that minimises Conditional Value-at-Risk (CVaR).Read moreRead less
Special Research Initiatives - Grant ID: SR0354804
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impac ....ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impacts of contaminated soil and wastes, and land remediation. By facilitating communication, the network enhances national and international research coordination, interaction with regulators, end-users, industry, and other stakeholders, achievement of critical mass for new initiatives, enhances research training and contributes to a critical National Priority.Read moreRead less
Liquidity in financial markets. This project aims to develop a theory which models the effect of liquidity on option prices under different market conditions. Economic or financial crises are inevitable and affect economics. During or after a major financial crisis, market liquidity usually becomes risky and needs to be studied. Through both empirical and theoretical explorations, this project will quantify and measure liquidity risk and its effect on the options markets. It will develop a frame ....Liquidity in financial markets. This project aims to develop a theory which models the effect of liquidity on option prices under different market conditions. Economic or financial crises are inevitable and affect economics. During or after a major financial crisis, market liquidity usually becomes risky and needs to be studied. Through both empirical and theoretical explorations, this project will quantify and measure liquidity risk and its effect on the options markets. It will develop a framework to help market regulators manage illiquidity, enhance the efficiency of option trading in illiquid markets and help in the detection of market manipulation.Read moreRead less
Heavy metal phytotoxicity in long-term contaminated soils: Implications for the development of Australian regulatory guidelines and realistic environmental risk assessment. Heavy metal contamination is a serious global environmental problem. There are >80,000 potentially contaminated sites in Australia alone with many of these sites in the urban environment and former mining areas. The current guidelines for phytotoxicity testing (National Environmental Protection Measure 1999) are based on tota ....Heavy metal phytotoxicity in long-term contaminated soils: Implications for the development of Australian regulatory guidelines and realistic environmental risk assessment. Heavy metal contamination is a serious global environmental problem. There are >80,000 potentially contaminated sites in Australia alone with many of these sites in the urban environment and former mining areas. The current guidelines for phytotoxicity testing (National Environmental Protection Measure 1999) are based on total metal concentrations that do not take into consideration of bioavailability and wide ranging Australian soil types. Serious concerns have been raised on the applicability of these guidelines and their protective limits in ecological risk assessment. This project aims at developing phytotoxicity guidelines applicable to a wide range of soil types common to Australia.Read moreRead less