Discovery Early Career Researcher Award - Grant ID: DE130100467
Funder
Australian Research Council
Funding Amount
$374,823.00
Summary
Limbs and wings: reconstructing Australian environmental change through innovative analysis of ancient mammal skeletons. An animal's skeleton is the product of a complex relationship between its habits, habitat and evolutionary history. This project uses a vast resource of World Heritage fossil skeletons from Riversleigh to determine how behaviour and ecology of Australia's mammals have changed over the last 25 million years and will need to adapt in the future.
Discovery Early Career Researcher Award - Grant ID: DE120100957
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Using ancient fossils and new methods to unravel Australian mammal evolution in deep time. This project will explore the evolution of Australia's unique mammal fauna by studying fossil mammals recently discovered at Tingamarra, a 55 million year old fossil site in north-eastern Queensland. In particular, it will help us understand the origin, radiation and diversification of Australia's iconic marsupials.
New Riversleigh: Bridging chasms in the Neogene of Australia. This project aims to investigate the evolution of Australia’s animals in the late Miocene, 10 - 5 million years ago. The team’s discovery of a remote fossil field west of and larger than the Riversleigh World Heritage Area opens a window into Australia’s past, linking those of Australia's older lush rainforest communities to those of its drier, more modern habitats. Radiometric dates indicate that sediments in this vast area are late ....New Riversleigh: Bridging chasms in the Neogene of Australia. This project aims to investigate the evolution of Australia’s animals in the late Miocene, 10 - 5 million years ago. The team’s discovery of a remote fossil field west of and larger than the Riversleigh World Heritage Area opens a window into Australia’s past, linking those of Australia's older lush rainforest communities to those of its drier, more modern habitats. Radiometric dates indicate that sediments in this vast area are late Miocene in age. This project will reveal how Australia’s wildlife responded to one of the world’s biggest climate changes and help better anticipate what will be required to ensure its survival into the future. Benefits include enhanced understanding about long-term biota/climate interactions and significant additions to Australia’s unique, internationally significant palaeontological artefacts.Read moreRead less
Dawn of the age of mammals in Australia: foundations for an island biota. This project aims to fill a profound gap in knowledge about the origins of the modern fauna on the island continent Australia. It will augment Australia’s national natural heritage, enhance international research collaboration, and provide critical baseline data for complementary research in biology, geology, geography and climatology. End users of this project include primary, secondary, tertiary and public education sect ....Dawn of the age of mammals in Australia: foundations for an island biota. This project aims to fill a profound gap in knowledge about the origins of the modern fauna on the island continent Australia. It will augment Australia’s national natural heritage, enhance international research collaboration, and provide critical baseline data for complementary research in biology, geology, geography and climatology. End users of this project include primary, secondary, tertiary and public education sectors and environment and heritage protection agencies.Read moreRead less
Role Of Brm In Skin Tumour Progression From Benign To Malignant
Funder
National Health and Medical Research Council
Funding Amount
$457,267.00
Summary
Australia has the highest incidence of skin cancer in the world. Skin cancer is 3 times as common as all other cancers combined and continues to increase in incidence, particularly in the aging population. Skin cancer is caused by exposure to the ultraviolet radiation found in sunlight. Ultraviolet radiation causes the appearance of solar keratosis, or sunspots, benign lesions that are not particularly dangerous to human health. Some of these develop into malignant squamous cell carcinomas that ....Australia has the highest incidence of skin cancer in the world. Skin cancer is 3 times as common as all other cancers combined and continues to increase in incidence, particularly in the aging population. Skin cancer is caused by exposure to the ultraviolet radiation found in sunlight. Ultraviolet radiation causes the appearance of solar keratosis, or sunspots, benign lesions that are not particularly dangerous to human health. Some of these develop into malignant squamous cell carcinomas that can spread to other tissues and are potentially fatal. Little is known about the biological mechanisms involved in solar keratosis development into squamous cell carcinomas. We have identified the gene brm as being involved in this process. It has not previously been recognised that this gene is important for skin cancer development and therefore our preliminary studies have identified a potential new target. We will study the role of this gene in ultraviolet radiation induced skin carcinogenesis, determine whether it is mutated by ultraviolet radiation in human skin cancer, and what role in plays in some key biological processes in skin cancer development. This study will expand our understanding of malignant conversion during human skin carcinogenesis, the most prevalent human cancer in Australia.Read moreRead less